Chemical Characterization and Ameliorating Effect of Extract against Polycystic Ovary Syndrome in Wistar Rats.

Polycystic ovary syndrome (PCOS) in females is an endocrine pathological condition of reproductive age which is usually caused by insulin resistance, hyperlipidemia, and oxidative stress. This research was aimed at evaluating the therapeutic effect of the seed extract (CA) against PCOS in rodents as it is traditionally used to treat diabetes, inflammation, and gynecological problems. The CA was chemically characterized by high-performance liquid chromatography-diode array detection (HPLC-DAD).

Edge valency-based entropies of tetrahedral sheets of clay minerals.

Humanity has always benefited from an intercapillary study in the quantification of natural occurrences in mathematics and other pure scientific fields. Graph theory was extremely helpful to other studies, particularly in the applied sciences. Specifically, in chemistry, graph theory made a significant contribution.

Some stable and closed-shell structures of anticancer drugs by graph theoretical parameters.

The eigenvalues are significant in mathematics, but they are also relevant in other domains like as chemistry, economics, and a variety of others. In terms of our research, eigenvalues are used in chemistry to represent not only the form of energy but also the various physicochemical aspects of a chemical substance. We must comprehend the connection between mathematics and chemistry.

Offshoring the scarring causes and effects of environmental challenges faced by the advanced world: an empirical evidence.

In contemplating the prospects of advanced world countries, researchers stand divided among two groups: one group crying "melting of glaciers" and the group denying global warming as a significant concern while reaping the fruits of growth. One persistent concern for the other group is much desirable economic growth at the cost of environmental degradation, which is now reaching a scale where the global climate is become not only unsustainable but also causing a significant threat to our existence. In our opinion, environmental degradation should be taken very seriously now, particularly by pointing out the necessary variables causing it so that effective policy designs are formulated.

Assessing the role of green supply chain management in enhancing Pakistan manufacturers' performances.

The purpose of this study is to explore the impact of success factors of Green Supply Chain Management (GSCM) dimensions (i.e., green purchasing, internal environmental management, cooperation with customers, eco-design, and investment recovery) and their impact on the Organizational Performance of Manufacturers in Pakistan on three pieces of levels of execution (i.

In Vitro/In Vivo Evaluation of Clomipramine Orodispersible Tablets for the Treatment of Depression and Obsessive-Compulsive Disorder.

The first and only antidepressant drug on the market with solid proof of clinically significant serotonin and noradrenaline reuptake inhibition is clomipramine (CLP). However, significant first-pass metabolism reduces its absorption to less than 62%. It is heavily protein-bound and broadly dispersed across the body (9-25 L/kg volume of distribution).

Comparison of SAME verses CIMT on upper-limb functions in chronic stroke: A pilot randomized control trial.

Objective: To compare the effects of Same Arm Movement Therapy versus Constraint Induced Movement Therapy in improving upper-limb functions in patients of chronic stroke.

Methods: The pilot, assessor-blind, randomised control trial was conducted from February to September 2020 at the Spine and Physiotherapy Rehab Centre, Riphah Rehabilitation Centre, Lahore, Pakistan, and comprised patients of either gender aged 30-60 years having any type of stroke for a minimum 3 months. They were randomised into group A which received same arm movement therapy for 8 weeks of mental rehearsal of upper limb movements during 45min supervised sessions three times a week and structured independent sessions twice a week, and group B which received constrain induced movement therapy for eight weeks of daily intensive training of the affected extremity for two hours per day, five days per week for eight weeks in association with restriction of the non-affected extremity for 10 hours a day.

Tetrahedral sheets of clay minerals and their edge valency-based entropy measures.

Humanity has always benefited from an intercapillary study in the quantification of natural occurrences in mathematics and other pure scientific fields. Graph theory was extremely helpful to other studies, particularly in the applied sciences. Specifically, in chemistry, graph theory made a significant contribution.

Some new results on the face index of certain polycyclic chemical networks.

Silicate minerals make up the majority of the earth's crust and account for almost 92 percent of the total. Silicate sheets, often known as silicate networks, are characterised as definite connectivity parallel designs. A key idea in studying different generalised classes of graphs in terms of planarity is the face of the graph.

Normative data of modified Romberg balance test for risk of fall in elderly population of Pakistan.

Objective: To generate normative data of modified Romberg balance test for the risk of fall among the elderly.

Methods: The crossectional study was conducted from July 1 to December 31, 2021, and comprised healthy adults of either gender aged 60 years and above from different cities of Pakistan. The participants were screened for balance issues using the Patient Reported Outcomes Measurement Information System Global Health Questionnaire.

Breast cancer chemical structures and their partition resolvability.

Cancer is a disease that causes abnormal cell formation and spreads throughout the body, causing harm to other organs. Breast cancer is the most common kind among many of cancers worldwide. Breast cancer affects women due to hormonal changes or genetic mutations in DNA.

An overview of biofeedback techniques in mechanical low back pain: effects on sensory integration of balance.

Low back pain is a common musculoskeletal disorder involving the lumbar spine. It affects almost 80% of the world's population and is associated with functional limitations. The reported global prevalence ranges from15-30%.

How workplace loneliness harms employee well-being: A moderated mediational model.

This study investigated the effect of workplace loneliness on work-related subjective well-being by proposing work engagement as an explanatory mechanism in the workplace loneliness-job dissatisfaction relationship. Moreover, the study examines the need to belong as a coping mechanism in the relationship between workplace loneliness and work engagement. Specifically, the study posits that workplace loneliness reduces the positive and fulfilling state of work engagement that in turn increases job dissatisfaction and that this mediation depends on the employee's level of need to belong.

Comparative study of vertex-edge based indices for semi-capped carbon nanotubes.

Manufacturing relatively inexpensive items in every area of engineering and science is the major focus of exploration resultant the world's contemporary economic setback. Making small-sized items that are inexpensive and lightweight while providing high quality is critical in today's and tomorrow's worlds. Nanotechnology has a significant role to play in this situation.

Quercetin-loaded chitosan nanoparticles ameliorate adjuvant-induced arthritis in rats by regulating anti-oxidant enzymes and downregulating pro- and inflammatory cytokines.

Rheumatoid arthritis (RA) is an inflammatory condition and associated with the symmetrical synovitis of the joints and cause joint pain. The use of anti-rheumatic drugs is associated with many adverse effects. Quercetin, an important polyphenolic flavonoid, possess anti-inflammatory and anti-rheumatic effects.

Synthesis of Al/starch co-doped in CaO nanoparticles for enhanced catalytic and antimicrobial activities: experimental and DFT approaches.

In this work, aluminum/starch (St)-doped CaO nanoparticles (NPs) were synthesized by a co-precipitation method to degrade harmful dyes in various pH media. Systematic characterization was performed to investigate the influence of Al/St dopants on the composition, crystal structure, functional groups present, optical characteristics, and morphology of CaO NPs. Further hybrid density functional analyses corroborated that the band gap energy was reduced as the Al concentration in starch-doped CaO is increased.

Examining computationally the structural, elastic, optical, and electronic properties of CaQCl (Q = Li and K) chloroperovskites using DFT framework.

This study presents the investigations of structural, elastic, optical, and electronic properties of CaQCl (Q = Li and K) chloroperovskites for the first time using the DFT framework. The WIEN2K and IRelast packages are used in which the exchange-correlation potential of the modified Becke-Johnson potential (TB-mBJ) is used for obtaining better results. The optimized crystal structural parameters comprising the lattice constant, optimum volume, ground state energy, bulk modulus, and the pressure derivative of bulk modulus are computed by fitting the primitive unit cell energy primitive unit cell volume using the Birch-Murnaghan equation of state.

Augmented Oral Bioavailability and Prokinetic Activity of Levosulpiride Delivered in Nanostructured Lipid Carriers.

The present study is aimed to develop and optimize levosulpiride-loaded nanostructured lipid carriers (LSP-NLCs) for improving oral bioavailability and prokinetic activity of LSP. LSP-NLCs were optimized with D-optimal mixture design using solid lipid, liquid lipid and surfactant concentrations as independent variables. The prepared LSP-NLCs were evaluated for physicochemical properties and solid-state characterization.

Computing the partition dimension of certain families of Toeplitz graph.

Let = ((), ()) be a graph with no loops, numerous edges, and only one component, which is made up of the vertex set () and the edge set (). The distance () between two vertices that belong to the vertex set of is the shortest path between them. A -ordered partition of vertices is defined as β = {β, β, …, β }.

Structural, electronic, magnetic and elastic properties of xenon-based fluoroperovskites XeMF (M = Ti, V, Zr, Nb) DFT studies.

In this work, the structural, electronic, magnetic and elastic properties of the xenon-based fluoroperovskites XeMF (M = Ti, V, Zr, Nb) have been studied using density functional theory. The structural study reveals that all the perovskites have stable structures. A half-metallic nature is observed due to the presence of a band gap in only the spin-down channel.

Applications of the Multiattribute Decision-Making for the Development of the Tourism Industry Using Complex Intuitionistic Fuzzy Hamy Mean Operators.

In the aggregation of uncertain information, it is very important to consider the interrelationship of the input information. Hamy mean (HM) is one of the fine tools to deal with such scenarios. This paper aims to extend the idea of the HM operator and dual HM (DHM) operator in the framework of complex intuitionistic fuzzy sets (CIFSs).

Kidney Cancer Prediction Empowered with Blockchain Security Using Transfer Learning.

Kidney cancer is a very dangerous and lethal cancerous disease caused by kidney tumors or by genetic renal disease, and very few patients survive because there is no method for early prediction of kidney cancer. Early prediction of kidney cancer helps doctors start proper therapy and treatment for the patients, preventing kidney tumors and renal transplantation. With the adaptation of artificial intelligence, automated tools empowered with different deep learning and machine learning algorithms can predict cancers.

Effects of 8 weeks functional training programme on posture control and functional mobility in spastic hemiplegic cerebral palsy.

Objective: To determine the impacts of functional training versus conventional training on posture control and functional mobility in spastic hemiplegic cerebral palsy children.

Methods: The randomised clinical trial was conducted at the Rehab Cure physiotherapy centre, Lahore, Pakistan, from January to September 2020, and comprised children of either gender aged 4-14 years, diagnosed with cerebral palsy, gross motor functional classification system level II or III, and no mental retardation. The subjects were randomised into conventional therapy group A and functional training group B.