3 results match your criteria: "Reviva Stem Cell Platform for Research and Applications Center[Affiliation]"
T-cell lymphocytes' aging clock: telomeres, telomerase and aging.
Biogerontology
April 2024
Univ. Bordeaux, INSERM, BRIC, U1312, 33000, Bordeaux, France.
Article Synopsis
- Aging is when our bodies slowly lose strength and abilities needed to stay alive and reproduce over time.!
- T-cells, a type of immune cell, change a lot as we get older, especially with things like telomeres and telomerase, which are important for keeping cells healthy.!
- This text reviews how these changes in T-cells relate to health, aging, and diseases, especially cancers linked to short telomeres and telomerase problems.!
Stem cell-based therapies have been foreshowed as a promising therapeutic approach for the treatment of several diseases. However, in the cancer context, results obtained from clinical studies were found to be quite limited. Deeply implicated in inflammatory cues, Mesenchymal, Neural, and Embryonic Stem Cells have mainly been used in clinical trials as a vehicle to deliver and stimulate signals in tumors niche.
View Article and Find Full Text PDFTherapeutic Potential of Human Immature Dental Pulp Stem Cells Observed in Mouse Model for Acquired Aplastic Anemia.
Cells
July 2022
Genetics Laboratory, Instituto Butantan, São Paulo 05503-900, Brazil.
Aplastic anemia (AA) is a rare and serious disorder of hematopoietic stem cells (HSCs) that results in the loss of blood cells due to the failure of the bone marrow (BM). Although BM transplantation is used to treat AA, its use is limited by donor availability. In this sense, mesenchymal stem cells (MSCs) can offer a novel therapeutic approach for AA.
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