8,929 results match your criteria: "Respiratory Acidosis"
Acta Paediatr
December 2024
Department of Neonatology, University Children's Hospital Tuebingen, Tuebingen, Germany.
Aim: Lung ultrasound (LU) and clinical parameters evaluated during the first postnatal hour potentially predict the length of CPAP therapy in newborns with respiratory distress.
Methods: In a single-centre, prospective observational pilot study, 130 newborns ≥36 weeks gestational age were assessed using standardised LU at 30 and 60 min postnatally. Various clinical parameters were evaluated influencing CPAP duration (<1 vs.
Geriatr Gerontol Int
September 2024
The Faculty of Medicine, Hebrew University and Hadassah Medical School, Jerusalem.
Syst Rev
August 2024
Department of Respiratory Medicine, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.
Background: Severe pneumonia has consistently been associated with high mortality. We sought to identify risk factors for the mortality of severe pneumonia to assist in reducing mortality for medical treatment.
Methods: Electronic databases including PubMed, Web of Science, EMBASE, Cochrane Library, and Scopus were systematically searched till June 1, 2023.
Andes Pediatr
June 2024
Universidad de Chile, Santiago, Chile.
Unlabelled: Congenital Central Hypoventilation Syndrome (CCHS) is a rare genetic condition affecting the autonomic nervous system and respiratory center due to mutations in the PHOX2B gene, and it is associated with alveolar hypoventilation during sleep and sudden death. It requires early invasive mechanical ventilation (IMV).
Objective: To report a neonatal case successfully treated with non-invasive ventilatory support (NVS), avoiding tracheostomy.
Cureus
July 2024
Pediatric Intensive Care Unit, Centro Materno Infantil do Norte, Centro Hospitalar Universitário do Porto, Porto, PRT.
Key Clinical Message: In managing Sjogren's syndrome, a thorough patient history, proper lab tests, and imaging are crucial. Clinicians should prioritize checking electrolyte levels in cases of muscle weakness, as early detection of hypokalemia can prevent severe complications. Proactive monitoring can avert renal tubular acidosis and improve patient outcomes.
View Article and Find Full Text PDFPediatrics
September 2024
Pediatric Hospital Medicine, Department of Pediatrics.
A 7-week-old infant presented to the emergency department with fussiness, decreased oral intake, loose stool, and respiratory distress for 2 days. The patient was born full-term with an uncomplicated birth history but had a history of slow weight gain. He was alert, but toxic-appearing at presentation, hypothermic with signs of dehydration, and with respiratory failure.
View Article and Find Full Text PDFRadiology
July 2024
From the Intensive Care and Resuscitation Unit (M.D., J.P., A.G., A.P., M.F.), Department of Pathological Anatomy and Cytology, Section of Oncology, Pathology and Molecular Biology (A.F., M.A.), Department of Radiology (A.M.), and Department of Pneumology and Thoracic Oncology and GRC-04 Theranoscan (A.P.), Groupe Hospitalier Universitaire APHP-Sorbonne Université, Hôpital Tenon, Paris, France; Department of Experimental and Clinical Respiratory Neurophysiology (UMRS 1158), INSERM, Sorbonne Université, Paris, France (M.D.); and Intensive Care and Resuscitation Unit (R3S), Groupe Hospitalier Universitaire APHP-Sorbonne Université, site Pitié-Salpêtrière, 47-83 Boulevard de l'Hôpital, 75013 Paris, France (M.D., J.P.).
A 58-year-old male patient with an active smoking status was admitted twice to the intensive care unit (ICU) of a tertiary referral thoracic center for severe hypercapnic acute respiratory failure and persistent bilateral chest radiograph opacities that were unchanged over the course of the two ICU admissions within a 3-month period. The patient had obesity (body mass index, 36), stage 3 vascular chronic renal insufficiency, and hebephrenic schizophrenia treated with haloperidol, carbamazepine, and cyamemazine. He reported chronic dyspnea on exertion, which worsened for 6 months.
View Article and Find Full Text PDFCureus
June 2024
Internal Medicine, Hayatabad Medical Complex Peshawar, Peshawar, PAK.
Cureus
June 2024
Department of Internal Medicine, Suwa Central Hospital, Nagano, JPN.
Lactic acidosis is associated with poorer clinical outcomes in critical care. The causes of this condition are divided into two groups: type A (tissue hypoxia) and type B (metabolic abnormalities). Of these, drug-induced lactic acidosis is categorized as type B and is often overlooked due to clinicians' poor awareness.
View Article and Find Full Text PDFCureus
June 2024
Intensive Care Department, Centro Hospitalar Lisboa Ocidental, Lisbon, PRT.
Indian J Tuberc
July 2024
Department of Respiratory Medicine, Indira Gandhi Government Medical College, Nagpur, Maharashtra, India.
Background: Monitoring and managing adverse drug reactions (ADR) are critical for treating drug-resistant tuberculosis (TB).
Objective: To study symptomatic, linezolid-attributable ADRs in TB patients initiated on all oral longer bedaquiline-based treatment regime for multidrug-resistant/rifampicin-resistant (MDR/RR)-TB under programmatic conditions.
Methods: It was a multicenter, retrospective study of people with MDR/RR-TB in nine TB units in Nagpur, India, from March 2020 to April 2022.
J Neurol
September 2024
Neuro-Intensive Care Unit, Department of Intensive Care, University Hospital of Geneva, Geneva, Switzerland.
Ear Nose Throat J
July 2024
Intensive Care Unit, Shandong Public Health Clinical Center, Shandong University, Jinan, Shandong, China.
The purpose of this article is to introduce a novel imaging device and technique for percutaneous dilatational tracheostomy (PDT) and evaluate its clinical application. We have modified the bronchoscope to generate a novel imaging device. The handle of the bronchoscope was removed and replaced with added fixation pieces to secure the new device to the endotracheal tube.
View Article and Find Full Text PDFObjective: The objective of this study was to investigate the correlation between metformin exposure and the incidence of lactic acidosis in critically ill patients.
Methods: The patients with type 2 diabetes mellitus (T2DM) were included from Medical Information Mart for Intensive Care IV database (MIMIC-IV). The primary outcome was the incidence of lactic acidosis.
Cureus
June 2024
Neurophysiotherapy, Ravi Nair Physiotherapy College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Am J Case Rep
July 2024
Department of Interventional Pulmonology, TidalHealth Peninsula Regional, Salisbury, MD, USA.
BACKGROUND Cryptococcosis is an invasive fungal infection caused by Cryptococcus species complex. C. neoformans is one of the pathogenic species within the genus.
View Article and Find Full Text PDFCureus
June 2024
Pulmonary and Critical Care Medicine, Ascension Macomb-Oakland Hospital, Warren, USA.
Acta Physiol (Oxf)
October 2024
Marine Biology Research Division, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA.
Aim: To identify the physiological role of the acid-base sensing enzyme, soluble adenylyl cyclase (sAC), in red blood cells (RBC) of the model teleost fish, rainbow trout.
Methods: We used: (i) super-resolution microscopy to determine the subcellular location of sAC protein; (ii) live-cell imaging of RBC intracellular pH (pH) with specific sAC inhibition (KH7 or LRE1) to determine its role in cellular acid-base regulation; (iii) spectrophotometric measurements of haemoglobin-oxygen (Hb-O) binding in steady-state conditions; and (iv) during simulated arterial-venous transit, to determine the role of sAC in systemic O transport.
Results: Distinct pools of sAC protein were detected in the RBC cytoplasm, at the plasma membrane and within the nucleus.
Vet Med Int
July 2024
Department of Para-clinical Studies, P.O. Box: 196University of Gondar, Gondar, Ethiopia.
Background: Grain overload is a ruminant metabolic disorder associated with overingestion or a sudden change to rapidly fermentable concentrate feeds.
Objective: A randomized clinical trial was carried out in Libo Kemkem districts to investigate vital signs, ruminal fluid, and hematological changes in sheep related to grain overload and to assess the treatment efficacy of various remedial agents in Farta sheep breeds.
Methods: All sheep were selected by using the simple random process, and categorized into four groups of eight animals groups I, II, and III in which each sheep was given 80 g of wheat flour per kg of body weight then baking soda, Magnalax, and digestive powder were treated successively, but group IV was the negative control group.
Cureus
June 2024
Department of Emergency Medicine, Fukuoka Kinen Hospital, Fukuoka, JPN.
Stroke mimics are difficult to differentiate from each other. Symptomatic epilepsy can also occur, but it is necessary to perform a magnetic resonance imaging (MRI) scan to distinguish it from a stroke. Although respiratory acidosis has been reported to occur with partial-onset seizures due to prolonged apnea, respiratory acidosis is rarely suspected to be a sign of epilepsy.
View Article and Find Full Text PDFClin Ter
July 2024
Unit of Pharmacology and Pharmacovigilance, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Medication errors pose significant risks to patients' health, representing a relevant social and economic issue for the healthcare system. This study focuses on the life-threatening consequences of an overdose of intravenous lipid emulsion (ILE), used as an antidote for suspected bupivacaine intoxication in a young woman undergoing hip surgery. Shortly after administration of the local anesthetic, the woman experienced cardiac arrest and was admitted to the intensive care unit with severe respiratory failure, metabolic acidosis and deep coma.
View Article and Find Full Text PDFCureus
June 2024
Department of Pediatrics, Division of Neonatology, University of Health Sciences, Bakırkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, TUR.
Introduction Intrapartum hypoxic-ischemic injury is a condition that significantly affects neonatal health and, therefore, needs to be attended to urgently. Umbilical cord blood gas analysis (BGA) results and APGAR (appearance, pulse, grimace, activity, and respiration) scores are commonly used to assess birth asphyxia and the severity of neonatal acidemia. In this context, this study was conducted to investigate the correlations of BGA results and APGAR scores with neonatal outcomes to determine the combined value of BGA results and APGAR scores in neonatal health assessment.
View Article and Find Full Text PDFJ Clin Med
June 2024
Department of Nephrology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
Brown tumors, an exceptional bone complication of severe primary (PHP) or renal (secondary) hyperparathyroidism (RHP), are caused by long-standing, elevated parathormone (PTH)-induced osteoclast activation causing multinucleated giant cell conglomerates with hemosiderin deposits in addition to the local production of cytokines and growth factors. We aim to present an adult case series including two females displaying this complication as part of a multidisciplinary complex panel in high PTH-related ailments. The approach was different since they had distinct medical backgrounds and posed a wide area of challenges amid real-life settings, namely, a 38-year-old lady with PHP and long-term uncontrolled hypercalcemia (with a history of pregnancy-associated PHP, the removal of a cystic jaw tumor, as well as a family and personal positive diagnosis of polycystic kidney disease, probably a PHP-jaw tumor syndrome), as well as, a 26-year-old woman with congenital single kidney and chronic renal disease-associated RHP who was poorly controlled under dialysis and developed severe anemia and episodes of metabolic acidosis (including one presentation that required emergency hemodialysis and was complicated with convulsive seizures, followed by resuscitated respiratory arrest).
View Article and Find Full Text PDFGastroenterol Hepatol Bed Bench
January 2024
Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.