3,391 results match your criteria: "Research and Development Institute[Affiliation]"

Given the constant increased number of nosocomial infections in hospitals, especially associated with prolonged usage of inserted medical devices, our work aims to ameliorate clinical experience and promote faster healing of patients undergoing urinary catheterization by improving the properties of medical devices materials. Within this research, nine different composites were prepared based on polyvinyl chloride, using three different plasticizers (di-(2-ethylhexyl) phthalate, Proviplast 2646, and Proviplast 2755), and two different antimicrobial additives containing silver nanoparticles. The prepared materials were analyzed, and their physicochemical properties were determined: water absorption, relative density, plasticizer migration, hydrophobicity/hydrophilicity by contact angle measurement, Shore A hardness, tensile strength, and elongation at break.

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Understanding the performance of polymer dielectrics at different temperatures is becoming increasingly important due to the rapid development of electric cars, electromagnetic devices, and new energy production solutions. Cyclic olefin copolymers (COCs) are an attractive material due to their low water absorption, good electrical insulation, long-term stability of surface treatments, and resistance to a wide range of acids and solvents. This work focused on the dielectric and electrical properties of cyclic olefin copolymer (COC)/AlO composites over a wide range of temperature and frequency domains, from room temperature to cryogenic temperatures (around 125 K).

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Globalization and free market dynamics have significantly impacted state economies, particularly in the wine industry. These forces have introduced greater diversity in wine products but have also heightened the risk of food fraud, especially in high-value commodities like wine. Due to its market value and the premium placed on quality, wine is frequently subject to adulteration.

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, a new species from south-western China and northern Vietnam, is described and illustrated. The new species is characterised by the glabrous surfaces on almost all plant parts, congested inflorescences and broad-ovate to ovate bracts 9-22 × 4-11 mm. It morphologically differs from the closest species, , mainly in most plant parts being glabrous, bracts broad-ovate to ovate, apex acute or sometimes obtuse, corollas inside with a ring of white hairs at the middle and anthers inserted near the middle in long-styled flowers.

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Article Synopsis
  • State-of-the-art all-solid-state batteries are set to outperform traditional Li-ion batteries by offering higher energy density and safety through lightweight and solvent-free polymeric electrolytes (SPEs).
  • To enhance the performance of SPEs, particularly at room temperature, adding natural resource fillers is being explored as a promising strategy to improve ionic conductivity and interfacial charge transport.
  • The study emphasizes using mineral and biobased fillers to replace synthetic materials, highlighting recent advances in SPE design, their challenges, and potential solutions for developing more sustainable rechargeable battery technologies.
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  • - Levels of progesterone increase after ovulation and are vital for supporting pregnancy, but gut microbiota can influence these levels by affecting the hormone's recycling in the liver and gut.
  • - A specific gut bacterium plays a key role in metabolizing progesterone into a neurosteroid, which does not have progestogenic activity; researchers identified the enzyme responsible for this conversion.
  • - In experiments with female mice, certain antibiotics helped restore progesterone levels, and prolonged antibiotic use disrupted ovarian follicle development, suggesting a link between gut bacteria and progesterone resistance in women.
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Sleep is crucial for children's health and eating habits. The decline in family meals has raised concerns about its impact on children. Previous research indicated associations between family meals and psychological health and dietary habits, but their relationship with sleep behavior is less understood.

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Humanized monoacylglycerol acyltransferase 2 mice develop metabolic dysfunction-associated steatohepatitis.

J Lipid Res

December 2024

The Institute of Metabolic Disorders, Genesis Research and Development Institute, Genesis Biotechnology Group, Hamilton, NJ, USA; Rutgers Center for Lipid Research, New Jersey Institute for Food, Nutrition, and Health, Rutgers University, New Brunswick, NJ, USA. Electronic address:

Mice lacking monoacylglycerol acyltransferase 2 (mMGAT2) are resistant to diet-induced fatty liver, suggesting hMOGAT2 inhibition is a viable option for treating metabolic dysfunction-associated steatotic liver disease (MASLD)/metabolic dysfunction-associated steatohepatitis (MASH). We generated humanized hMOGAT2 mice (HuMgat2) for use in pre-clinical studies testing the efficacy of hMOGAT2 inhibitors for treating MASLD/MASH. HuMgat2 mice developed MASH when fed a steatotic diet.

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sp. nov. is described from decaying wood submerged in a freshwater stream in Taiwan.

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Establishing an Interactive Sequence Database for Shiitake Cultivar Identification.

J Basic Microbiol

January 2025

Department of Biomedical Science and Environment Biology, Kaohsiung Medical University, Kaohsiung, Taiwan (ROC).

Shiitake mushrooms (Lentinula edodes) hold significant cultural and economic value, particularly in Asia where they are extensively cultivated. The diversification of shiitake cultivars, driven by the need to adapt to various climatic conditions and cultivation methods, has resulted in over 200 distinct cultivars. Reliable identification of these cultivars is crucial for breeding, intellectual property protection, and effective genetic resource management.

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Background: Intracavernous (IC) injections of stem cells has been shown to ameliorate cavernous nerve (CN)-induced erectile dysfunction (ED). However, the regenerative effects underlying the recovery of erectile function (EF) in human amniotic fluid-derived stem cells (hAFSCs) remain unclear. In the bilateral cavernous nerve crushing (BCNC) injury rat paradigm, we sought to ascertain the effects of hAFSC treatment on EF recovery during the incipient phase.

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  • A fungal pathogen affecting low-input apple production has become more widespread in Europe over the past 15 years, yet little is known about its biology and ability to cause disease.
  • This study focused on strain DC1_JKI from Germany, which was sequenced to achieve a comprehensive genome assembly, revealing a mating-type locus identified as MAT1-2.
  • Analysis across European and Asian samples showed that only MAT1-2 was present in European samples, potentially explaining the absence of the sexual reproduction form of the pathogen in European apple orchards.
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Pollen traps, the current gold standard to determine pollen load and thereby the allergy season, are not sufficient to determine the allergenic risk. Therefore, the establishment of highly sensitive assays for allergen measurement is of highest interest. Herein, a graphene field-effect transistor (GFET) was constructed on an interdigitated electrodes chip to develop an immersible biosensor, which was used to detect the major birch pollen allergen Bet v 1.

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This study develops a model to raise public awareness about the consequences of burning rice straw after harvest, including environmental pollution, soil degradation, and increased CO emissions that contribute to the greenhouse effect. The distinctive feature of the research is the introduction of a post-harvest rice straw treatment process using microbial products capable of secreting cellulase enzymes, which can break down the cellulose in the straw. This process shortens the decomposition time and produces natural organic fertilizer, thus reducing cultivation costs by 60% and increasing crop yields by 20%.

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  • - Hydroxyapatite (HAp) and its composites, which incorporate metal nanoparticles like copper, zinc, and silver, show great potential in healthcare due to their biocompatibility and strong antimicrobial properties, making them useful in preventing infections in medical settings.
  • - The study examined the antimicrobial efficacy of various HAp-based materials using advanced techniques, finding that all modified composites could inhibit bacterial growth, with the 5% silver-loaded variant (5% Ag/HAp) demonstrating the strongest antibacterial effects against E. coli and S. aureus.
  • - Results suggest that these HAp-based composites could effectively be used in infection control applications, such as on medical instruments and textiles, thereby improving safety in healthcare environments.
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Airborne dust and bioaerosols in Canadian conventional and alternative houses for laying hens.

J Occup Environ Hyg

December 2024

Département de Biochimie, de Microbiologie et de Bio-informatique, Faculté des Sciences et de Génie, Université Laval, Quebec City, Quebec, Canada.

Awareness about laying hen welfare has led to the phase-out of conventional battery cages in favor of the adoption of alternative housing systems for egg production in many countries. However, the greater freedom of movement for animals and the presence of manure and litter (sawdust, straw, feathers, etc.) on the floor in some alternative housing systems may be suitable conditions for dusts, bacteria, and fungi to be aerosolized, raising concerns about indoor air quality and respiratory health of workers.

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Mobile applications have been shown to be an effective and feasible intervention medium for improving healthy food intake in different target groups. As part of the PeRsOnalized nutriTion for hEalthy livINg (PROTEIN) European Union H2020 project, the PROTEIN mobile application was developed as an end-user environment, aiming to facilitate healthier lifestyles through artificial intelligence (AI)-based personalised dietary and physical activity recommendations. Recommendations were generated by an AI advisor for different user groups, combining users' personal information and preferences with a custom knowledge-based system developed by experts to create personalised, evidence-based nutrition and activity plans.

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Background: It is well known that periodontitis affects the gums and surrounding connective tissue. The chronic inflammatory response induced by bacteria in the gingival tissue leads to the loss of the collagen connection between the tooth and the bone and ultimately to bone loss.

Methods: In this context, the aim of this research was the obtaining and characterization of a drug release supports in the form of sponges based on collagen, hyaluronic acid as a support and metronidazole as an antibiotic for the treatment of periodontitis.

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Although impactful scientific advancements have recently been made in cancer therapy, there remains an opportunity for future improvements. Immunotherapy is perhaps one of the most cutting-edge categories of therapies demonstrating potential in the clinical setting. Genetically engineered T cells express chimeric antigen receptors (CARs), which can detect signals expressed by the molecules present on the surface of cancer cells, also called tumor-associated antigens (TAAs).

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Inoculating sulfate-reducing bacteria (SRB) habitats offers an eco-friendly method for treating sulfate-metal laden wastewater, characterized by high sulfate levels, low pH, and elevated heavy metals. This study optimizes source habitat selection of SRB by evaluating groundwater, sewage sludge, and lake sediment, focusing on their suitability and adaptability to aerobic-anaerobic transitions in industrial settings. Sewage sludge, with its slightly acidic pH, reducing environment, and high nutrient levels (Total organic carbon: 207.

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Divergent Heat Stress Responses in and .

Insects

September 2024

Food Futures Institute, Murdoch University, Perth, WA 6150, Australia.

Article Synopsis
  • *This study investigates how Qfly's molecular response to heat stress differs from that of Medfly by analyzing gene expression changes before and after heat treatment.
  • *Only three genes—HSP70, HSP68, and 14-3-3 zeta protein—were found in common between the two species, but their expression patterns varied, suggesting different regulatory mechanisms and potential implications for pest control strategies.
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A Brain-Computer Interface (BCI) processes and converts brain signals to provide commands to output devices to carry out certain tasks. The main purpose of BCIs is to replace or restore the missing or damaged functions of disabled people, including in neuromuscular disorders like Amyotrophic Lateral Sclerosis (ALS), cerebral palsy, stroke, or spinal cord injury. Hence, a BCI does not use neuromuscular output pathways; it bypasses traditional neuromuscular pathways by directly interpreting brain signals to command devices.

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Recent studies have explored surface treatments, such as increasing the hydrophilicity of implant fixtures, to enhance the osseointegration of implants. This prospective clinical study aimed to assess the clinical stability and efficacy of plasma treatment applied to implants with sandblast-acid etching (SLA) surfaces before placement. Twenty-eight patients requiring implant placement provided consent and were assigned randomly to either the SLA group without plasma treatment or the SLA/plasma group with plasma treatment.

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Article Synopsis
  • - The study focuses on comparing the effectiveness of real-time PCR and culture methods in detecting pathogens in children with severe community-acquired pneumonia (sCAP).
  • - Out of 336 samples, real-time PCR identified pathogens in 312 cases (92.9%), while culture identified them in 228 cases (67.9%), with a significant number (83.0%) showing coinfections via PCR.
  • - Results suggest real-time PCR is more efficient than culture for pathogen detection in sCAP, emphasizing its usefulness for fast and accurate identification of infections in pediatric patients.
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