6,157 results match your criteria: "Research and Development Centre[Affiliation]"

Amadori compounds (ACs) are key intermediates of the Maillard reaction, and found in various thermally processed foods. Simultaneous analysis of multiple ACs is challenging due to the complex amino acid and carbohydrate compositions, and the different food matrices. Most studies focus on the effects of ACs on food flavor and related sensory properties, but not their biological functions.

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RNA modifications in plant biotic interactions.

Plant Commun

December 2024

State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, China. Electronic address:

The chemical modification of DNA and proteins is an efficient way of regulating molecular and biological function and affects a plethora of signalling pathways in eukaryotes. Similarly, recent progress in epitranscriptomics shows that RNA modifications also play crucial roles in diverse biological processes. Since their discovery in the 1970s, scientists have attempted to decipher the identity and functions of these modifications in different biological systems.

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Treated wastewater reuse and its impact on soil properties and potato and corn growth.

Sci Total Environ

December 2024

Ottawa Research and Development Centre, Agriculture and Agri-Food Canada, 960 Carling Avenue, Ottawa K1A 0C6, ON, Canada. Electronic address:

Water scarcity is a growing challenge in semi-arid regions. Many farmers have resorted to treated wastewater (TWW) as an available and low-cost water source. This study investigated the impact of irrigating potato (Solanum Tuberosum) and corn (Zea mays) with tertiary-treated (TW) and secondary-treated (SW) wastewater compared to freshwater, over two years.

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The gastric digestion behavior of different commercial Stage 1 infant formulae (for 0-6 months) with different formulation backgrounds was investigated using an dynamic infant human gastric simulator (iHGS). The microstructural arrangements of the protein and lipid, colloidal stability and protein hydrolysis during digestion were elucidated. During gastric digestion, casein-dominant formulations showed a higher extent of aggregation due to their high proportion of casein micelles that underwent coagulation upon acidification and via the action of pepsin.

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During the transition period, the incidence of diseases increases due to a negative energy balance that affects metabolic and immune status. Limiting milk production at the beginning of lactation by milking once a day or by incompletely milking twice a day improves the metabolic and immune status of cows. Previous studies have shown that milk production is highly responsive to additional MP.

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The aim of this study was to examine how silages from different grassland species and harvesting frequencies affect feed intake, milk production, and methane (CH) emission in dairy cows. We hypothesized that cows consuming silages of more frequent harvest, grass species with greater organic matter digestibility and legumes with lower NDFom concentration would have greater silage dry matter intake and milk yield and thereby lower CH yield and intensity. Forty Norwegian Red cows were allocated to 5 treatments in a cyclic changeover design with 4 21-d periods (14 d of adaptation, 7 d of data collection).

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THE EFFECTS OF TECHNICAL STEPS USED IN EXISTING SANITATION HELMINTH TEST METHODS ON ASCARIS SUUM EGG RECOVERY FROM PIG FECES.

J Parasitol

December 2024

Water, Sanitation and Hygiene Research and Development Centre, Howard College Campus, University of KwaZulu-Natal, Durban 4041, South Africa.

Many technical aspects are associated with helminth egg isolation and enumeration that affect how efficiently eggs are recovered from samples. This study investigated Ascaris egg recoverability when samples were washed with or without pressure, and from different sample types (water, effluent, ventilated improved pit latrine [VIP], urine diversion dry toilet [UDDT], dried, fatty, and septic tank sludges, and soil) when processed with water, ammonium bicarbonate, and 7X®. We also looked at egg recovery after flotation with zinc sulfate, magnesium sulfate, and sodium nitrate at specific gravities of 1.

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Unlabelled: Dietary fibers influence the composition of the human gut microbiota and directly contribute to its downstream effects on host health. As more research supports the use of glycans as prebiotics for therapeutic applications, the need to identify the gut bacteria that metabolize glycans of interest increases. Fructo-oligosaccharide (FOS) is a common diet-derived glycan that is fermented by the gut microbiota and has been used as a prebiotic.

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Poplar Leaf Bud Resin Metabolomics: Seasonal Profiling of Leaf Bud Chemistry in Populus trichocarpa Provides Insight Into Resin Biosynthesis.

Plant Cell Physiol

December 2024

Centre for Forest Biology & Department of Biology, University of Victoria, 3800 Finnerty Road, Victoria, British Columbia, V8P 5C2, Canada.

Trees in the genus Populus synthesize sticky and fragrant resins to protect dormant leaf buds during winter. These resins contain diverse phenolic metabolites, in particular hydroxycinnamate esters and methylated flavonoids. P.

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This study investigated the role of fish in addressing food and nutrition security challenges in Southern Africa, focusing on 10 countries including Angola, Zambia, Malawi, Mozambique, Namibia, Botswana, Zimbabwe, Lesotho, Eswatini, and South Africa. It examined the current state of food and nutrition security, fish production, and fish consumption patterns. Additionally, the study investigated the challenges and opportunities to enhance fish production in these countries thereby enhancing food and nutrition security.

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Fatty acids are a requirement for normal development, however, since humans are unable to de novo produce essential fatty acids, they must be obtained from diet. Atlantic salmon is a major dietary source of nutritious and digestible fatty acids. Here, we set out to uncover the genomic basis of individual fatty acids and indices (saturated fatty acids, monounsaturated fatty acids, polyunsaturated fatty acids, n-3, and n-6) in 208 North American Atlantic salmon, to understand selection potential toward increasing relative quantities of essential fatty acids and to identify candidate genes for future research.

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IN SILICO BASED RE-ENGINEERING OF A COMPUTATIONALLY DESIGNED BIOSENSOR WITH ALTERED SIGNALLING MODE AND IMPROVED DYNAMIC RANGE.

Arch Biochem Biophys

December 2024

Alberta RNA Research and Training Institute (ARRTI), University of Lethbridge, Lethbridge, AB, Canada; Department of Chemistry and Biochemistry, University of Lethbridge, Lethbridge, AB, Canada.

A current challenge in the rational design of biomolecular sensors is the ability to custom design binding affinities and detection mode in silico. To this end, we re-engineered a previously reported computationally-designed fluorescent maltooligosaccharide (MOS)-detecting biosensor to both alter its ligand-binding affinity and to analyse the underlying sensing mechanism. The dynamic range of the biosensor was expanded through the computer aided introduction of a series of amino acid substitutions in the starting protein scaffold (MalX from Streptococcus pneumoniae), which generated a biosensor set with binding affinities spanning over five orders of magnitude.

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The amino acid (AA) content of multiple samples of various dairy powders was determined, providing a comprehensive evaluation of the differences in AA profiles attributable to distinct manufacturing processes. Products examined included whole milk powder (WMP), skim milk powder (SMP), cheese whey protein concentrate (WPC-C), lactic acid casein whey protein concentrate (WPC-L), high-fat whey protein concentrate (WPC-HF), hydrolyzed whey protein concentrate (WPH), whey protein isolate (WPI), and demineralized whey protein (D90). WMP and SMP exhibited broadly similar AA profiles, with minor differences likely due to the minimal milk fat protein content, which is nearly absent from SMP.

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Hydroxyl-based acid-hypersensitive acetal ester bond: Design, synthesis and the application potential in nanodrugs.

Eur J Med Chem

December 2024

State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China. Electronic address:

Article Synopsis
  • Targeted drug delivery systems are utilizing the acidic environment of tumors to improve drug stability and reduce toxicity through modifications like hydroxyl groups.
  • A newly developed "acetal ester bond" offers a highly sensitive and easy-to-synthesize linkage that allows for efficient drug release specifically in acidic conditions while maintaining stability in healthy physiological environments.
  • The acetal ester bond-based paclitaxel conjugate (PTX-COU) demonstrated superior tumor growth inhibition in experiments, suggesting its potential for enhancing targeted drug delivery and minimizing systemic side effects.
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A Longitudinal Analysis Comparing the Mental Health of Children By Level of Young Carer Status.

J Adolesc

December 2024

DECIPHer (Centre for Development, Evaluation, Complexity and Implementation in Public Health Improvement), School of Social Sciences, Cardiff University, Cardiff, UK.

Introduction: Young carers research has predominantly focused on the experiences of children who often provide substantial levels of care for family members, and the impacts of this caring on their lives. While quantitative studies of prevalence have increased, there have been increasing calls for cross-sectional and longitudinal studies of young carers relative to children without caring responsibilities, to strengthen and challenge the existing evidence on impact.

Methods/materials: The study utilized the Longitudinal Study of Young People in England: Next Steps (LSYPE), a cohort study of over 12,500 children aged 13 in 2004.

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Mixed linkage (1,3;1,4)-β-d-glucan (MLG) is a well-recognized bioactive carbohydrate and dietary fibre with expanding applications in food industry. The MLG are small components of the cell wall of vegetative tissues of cereals synthetized by members of the genes (). Within the family, the has been the major contributor in wheat.

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Functional foods are considered the future of nutrition because they benefit human health and environmental sustainability. They offer natural solutions for managing post-prandial glycemia and its long-term consequences. Therefore, understanding the composition and inherent dynamics of the functional food matrix (FM) is crucial.

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Calcium signaling triggers early high humidity responses in .

Proc Natl Acad Sci U S A

December 2024

Department of Cell and Systems Biology, University of Toronto, Toronto, ON M5S3B2, Canada.

Plants need to adapt to fluctuating atmospheric humidity and respond to both high and low humidity. Despite our substantial understanding of plant responses to low humidity, molecular mechanisms underlying the high humidity (HH) response are much less well understood. In this study, we investigated early responses to HH in .

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A comparative assessment of the thermal properties and heat transfer coefficients achieved by viscoelastic nanofluids suitable for immersion cooling is presented, with the candidate samples exhibiting distinct differences based on the nanoparticle chemistry and shape. Molecular dynamics simulations of different nanoparticles such as copper nanosphere, two-dimensional pristine graphene, and single-walled carbon nanotube (CNT) dispersed in PAO-2 of concentrations of approximately equal to 2.6% by weight are performed in the present investigation.

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A recent study assessed the ability of 4 feed evaluation models to predict milk protein yield (MPY) in a commercial context, with data of 541 cows from 23 dairy herds in the province of Québec, Canada. However, the recently published Nutrient Requirements of Dairy Cattle from the National Academies of Sciences, Engineering, and Medicine (NASEM, 2021) was not released at that time. Thus, the current study evaluated NASEM using the same dataset.

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The strawberry blossom weevil, Anthonomus rubi (Herbst) (Coleoptera: Curculionidae), is native to Europe, Asia, and parts of North Africa, and has recently established in British Columbia, Canada and Washington State, USA. To determine whether any parasitoids in British Columbia parasitize this recently-established pest, A. rubi-infested buds of Rosaceous host plants were collected and reared for parasitoid emergence.

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Meat product labels including information on livestock production systems are increasingly demanded, as consumers request total traceability of the products. The aim of this study was to explore the potential of visible and near-infrared spectroscopy (Vis-NIRS) to authenticate meat and fat from steers raised under different feeding systems (barley, corn, grass-fed). In total, spectra from 45 steers were collected (380-2,500 nm) on the subcutaneous fat and intact longissimus thoracis (LT) at 72 h postmortem and, after fabrication, on the frozen-thawed ground longissimus lumborum (LL).

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Urease and nitrification inhibitors can reduce ammonia and greenhouse gas emissions from fertilizers and manure but their effectiveness depends on the conditions under which they are used. Consequently, it is essential for the credibility of emission reductions reported in regulatory emission inventories that their effectiveness is assessed under real-world conditions and not just in the laboratory. Here, we specify the criteria we consider necessary before the effects of inhibitors are included in regulatory emission inventories.

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