Whey proteins from camel's milk have higher in vitro wound-healing effect than whey proteins from cow's milk.

Background: The effectiveness of whey obtained by either enzyme (sweet) or acid treatment on wound healing remains unclear. This study investigated the effectiveness of camel and bovine whey prepared enzymatically (CSW and BSW) or by pH reduction (CAW and BAW). After removing the cream from milk, HCl or rennet was used to remove casein, resulting in acid or sweet whey, respectively, followed by lactose removal using dialysis.

Development of Electrically Conductive Wood-Based Panels for Sensor Applications.

This study investigates the development of electrically conductive panels for application as emergency detection sensors in smart house systems. These panels, composed of wood chips coated with polymeric methylene diphenyl isocyanate, were modified with carbon black and carbon fibers to enable detection of moisture, temperature, and pressure variations. Manufactured via hot pressing, the panels retained standard mechanical properties and exhibited stable performance under diverse environmental conditions.

Formulation, characterization and evaluation of minocycline hydrochloride loaded polyurethane/collagen nanofibers via electrospinning as wound dressings.

Objective: It was aimed to formulate minocyline. HCI loaded electrospun polyurethane/collagen (PU/Col) and polyurethane/collagen/polycaprolactone (PU/Col/PCL) nanofibers are intended for use as a wound dressing.

Methods: The effect of polymer ratio and addition of PCL on the morphology, diameter, drug delivery, encapsulation efficiency, mechanical properties, antibacterial activity against and , cytotoxicity, cell adhesion and proliferation were investigated.

Manipulation of defect state emission in Zn chalcogenide quantum dots and their effects on chlorophyll spectral response.

Water soluble Zn based quantum dots (QDs) are of interest due to their biocompatibility and less toxic features. They have been frequently used in studies related to biotechnology, especially in agriculture studies. However, to control the optical properties of Zn based QDs has still been a challenge.

Delivery of proapoptotic gene in Peptide-18-targeted Poly(2-oxazoline)-DOPE nanoliposomes for breast cancer models.

Breast cancer is one of the most common cancers and a significant cause of death in females worldwide. For effective breast cancer treatment, using systems with a promising delivery of anticancer agents is an important strategy. Peptide 18 (P18), a tumor-homing peptide, shows a high binding affinity toward breast cancer cells.

Phthalate exposure induces cell death and ferroptosis in neonatal microglial cells.

Background/aim: Phthalates are the materials used for plasticizing polyvinyl chloride. Di-(2-Ethylhexyl) phthalate (DEHP) is one of the phthalates most frequently used in a wide range of applications, including medical equipment such as endotracheal and feeding tubes, intravenous catheters, central lines, extracorporeal membrane oxygenation sets, total parenteral nutrition bags, blood product sets, and intravenous pump lines, respiratory sets in neonatal intensive care units (NICUs). Studies have shown that phthalates, including DEHP, can cross the placenta and blood-brain barrier, possibly leading to neurodevelopmental impairment in vitro and in vivo.

Identification and full-length genome characterization of a novel mitovirus hosted by the truffle species .

Unlabelled: Studying the diversity of viruses found in uncultivated fungi, including those forming mycorrhizal relationships, is essential. It's equally important to explore viral communities in fungi that cause plant diseases or are economically significant. This dual approach helps us grasp the full scope of mycovirus diversity and evolution.

Manufacturing Radially Aligned PCL Nanofibers Reinforced With Sulfated Levan and Evaluation of its Biological Activity for Healing Tympanic Membrane Perforations.

The main objective of this study is to construct radially aligned PCL nanofibers reinforced with levan polymer and investigate their in vitro biological activities thoroughly. First Halomonas levan (HL) polysaccharide is hydrolyzed (hHL) and subjected to sulfation to attain Sulfated hydrolyzed Halomonas levan (ShHL)-based material indicating heparin mimetic properties. Then, optimization studies are carried out to produce coaxially generated radially aligned Poly(caprolactone) (PCL) -ShHL nanofibers via electrospinning.

Bending Performance of Reinforced Concrete Beams with Rubber as Form of Fiber from Waste Tires.

An investigation was conducted to assess the efficacy of using waste rubber as a substitute for a portion of an aggregate to enhance concrete's sustainability. For the purpose of accomplishing this objective, a total of 12 specimens were constructed and then subjected to a series of tests to investigate their bending behavior. The samples were constructed with the following dimensions: 1000 mm length and a 100 mm by 150 mm cross-sectional area.

Mitigates Fructose-Induced Non-Alcoholic Fatty Liver in Rats.

Non-alcoholic fatty liver disease (NAFLD) is a growing global health concern closely linked to metabolic disorders, including obesity, insulin resistance, and dyslipidemia. Emerging evidence suggests that the gut-liver axis plays a critical role in the pathogenesis of NAFLD, with recent research highlighting the influence of gut microbiota, including fungal species such as Saccharomyces boulardii (). This study aimed to evaluate the effects of on lipid metabolism and oxidative stress in a rat model of fructose-induced NAFLD.

Love of life and flourishing in Turkish youth: mediating effects of optimism and hope.

The concept of love of life, which refers to a positive attitude towards one's own life, care for it and attachment to it, has recently captured the attention of researchers in the field of positive psychology. Despite its growing importance, there is a lack of research investigating the underlying mechanisms through which love of life impacts the flourishing and well-being of individuals. For the first time, the present study examined the mediating roles of optimism and hope in the association between love of life and flourishing in Turkish youth.

Curcumin-loaded emulsome nanoparticles induces apoptosis through p53 signaling pathway in pancreatic cancer cell line PANC-1.

Pancreatic cancer is a global health problem with a poor prognosis, limited treatment options and low survival rates of patients. Thus, the exploration of novel treatment approaches is crucial. Curcumin shows promise in pancreatic cancer.

The effect of Mobile-Assisted training and counseling on nurses' ventrogluteal injections application of nursing: A mixed method study.

Background: Nurses often administer intramuscular (IM) injections. However, they do not use the ventrogluteal (VG) site, although it is highly recommended.

Aim: This study investigated whether a mobile-assisted training and counseling program (intervention) encouraged nurses to use the VG site to administer IM injections.

Synthesis of Sulfonamide-Based Schiff Bases as Potent Anticancer Agents: Spectral Analyses, Biological Activity, Molecular Docking, ADME, DFT, and Pharmacophore Modelling Studies.

The current study focuses on the synthesis and characterization of six benzenesulfonamide-based Schiff base derivatives (7-12) with various electron-withdrawing and electron-donating substituents (-F, -CI, -Br, -CH, and -OCH) and the assessment of their antiproliferative activities against human lung (A549) and liver (HepG2) cancer cell lines using in vitro and in silico approaches. The structures of the synthesized compounds (7-12) were elucidated by elemental analysis and FT-IR, 1D (H, C, APT, and DEPT-135), and 2D (HMQC and HMBC) NMR spectroscopies. The cytotoxic activities of the targeted compounds were determined at various concentrations against these cancer cell lines for 72 h, using the MTT method.

Octylamine-oxalic acid (Oct-Oxa) deep eutectic solvent for the separation of Sudan II from food samples.

This work presents a novel deep eutectic solvent (DES) formed of octylamine and oxalic acid (Oct-Oxa) that was effectively used to separate Sudan II dye from food and water samples. The prepared DES was characterized using Fourier transform infrared spectroscopy (FT-IR) and carbon-13 nuclear magnetic resonance (C NMR). Key parameters were optimized, including a short ultrasonication time of 30 s and a very low DES volume of only 500 μL that could be separated within one minute of centrifugation.

Transforming plant-based waste and by-products into valuable products using various "Food Industry 4.0" enabling technologies: A literature review.

The last several years have seen unprecedented strain on food systems as a result of pandemics, climate change, population growth, and urbanization. Thus, academic and scientific communities now view global food security as a critical issue. However, food loss and waste are a major challenge when adopting food security and sustainability strategies, since a large proportion of food is lost or wasted along the food supply chain.

Effect of radiation dose rates and cisplatin on cytogenetic damage in rats receiving head-neck radiotherapy.

Background: We aimed to investigate effect of radiotherapy (RT) applications with different dose rates on cytogenetic damages, which focused on micronucleus (MN) formation, and evaluate how this damage varies by cisplatin in rats receiving head-neck RT.

Material And Methods: Thirty-six Sprague Dawley rats were divided into five groups. The first and second groups were irradiated at a dose rate of 300 monitor unit/minute (MU/min) and 600 MU/min, respectively.

Two-Dimensional TiS Nanosheet- and Conjugated Polymer Nanoparticle-Based Composites for Sensing Applications.

The assessment of phenolic compounds in food samples, environmental samples, and medical applications has gained importance recently. Here, we present research on novel conjugated polymer nanoparticles (P-PimBzBt NPs) and their composites with two-dimensional titanium disulfide nanosheets (2D-TiS) for electrochemical tyrosinase (TYR)-based catechol detection. P-PimBzBt NPs are decorated with 2D-TiS to enhance the electrochemical performance for biosensing.

tVNS alters inflammatory response in adult VPA-induced mouse model of autism: evidence for sexual dimorphism.

Autism is a neurodevelopmental disorder with limited treatment alternatives and which incidence is increasing. Some research suggests that vagus nerve simulation might lead to the reduction of certain symptom. Therefore, we aimed to examine the effect of bilateral transcutaneous auricular vagus nerve stimulation (tVNS) on the inflammatory response in an adult valproic acid (VPA) induced mouse (C57BL6) model of autism for the first time.