[An interim analysis of the results of treatment program implementation with the use of injectable extended-release naltrexone for opioid addicted patients].

Aim: To analyze outcomes of treatment in the 'Point of soberness' program for opioid addicted patients (2015-2016 гг.).

Material And Methods: The results of treatment of 83 opioid addicted patients were analyzed.

[Cardiac damage in liver cirrhosis in alcohol abusers].

Aim: to estimate the contribution of liver cirrhosis (LC) to the development of heart diseases in alcohol abusers.

Subjects And Methods: The investigation included 80 patients with alcoholic LC without a history of cardiovascular and respiratory diseases and, as a control group, 32 alcohol abusers without a history of chronic diseases of the liver and cardiovascular and respiratory systems; 45 patients with alcoholic cardiomyopathy (ACM) and congestive heart failure without a history of coronary heart disease and valvular diseases, among whom 11 patients were found to have LC. In addition to standard clinical examination, all the patients underwent electrocardiography, by estimating the corrected QT interval (QTc), standard echocardiography; and those without ACM underwent estimation of left ventricular (LV) kinetics using speckle-tracking echocardiography.

[The prevalence of the use of narcotics and other psychoactive substances in Russia today].

The epidemiological analysis of morbidity in drug addiction in Russia for the period of 25 years is presented. As shown in this analysis, by 1992 the number of drug addicts rose twofold in comparison with 1986, and by 1998 this number rose tenfold, reaching 109.5 per 100,000 of the population.

[The prevention of HIV infection in abusers of psychoactive substances as a social behavioral problem].

This research has made it possible to outline and illuminate a range of problems which should be solved in planning concrete measures for the prophylaxis of HIV infection among the users of psychoactive substances. Such measures should also include those aimed at preventing children and adolescents from getting accustomed to the use of drugs at an early age, as well as the search of ways for providing adequate and effective information on the consequences of using narcotic drugs, the prevention of passage from single cases of the tentative use of drugs to systematic narcotization, etc.