6 results match your criteria: "Research Institute of Cytology and Genetics[Affiliation]"
Burden of injury along the development spectrum: associations between the Socio-demographic Index and disability-adjusted life year estimates from the Global Burden of Disease Study 2017.
Inj Prev
October 2020
Institute for Health Metrics and Evaluation, University of Washington, Seattle, Washington, USA.
Article Synopsis
- - The study investigates how sociodemographic factors relate to injury-related health outcomes worldwide, specifically analyzing disability-adjusted life years (DALYs) from injuries across 195 countries from 1990 to 2017.
- - Findings show that while most injury causes display a trend of decreasing DALY rates with higher Socio-demographic Index (SDI), certain injuries like road injuries, interpersonal violence, and self-harm deviate from this trend, indicating complex underlying factors.
- - The research highlights the importance of understanding these injury patterns to improve health strategies and intervention efforts at both national and global levels, especially since not all injuries follow the same developmental trajectory.
Relationships between Body Composition and Plasma Levels of Pancreatic, Gut, and Adipose Tissue Hormones in db/db Mice, a Model of Type 2 Diabetes Mellitus.
Bull Exp Biol Med
July 2019
Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia.
We studied the relationships between body composition parameters and plasma levels of pancreatic, gut, and adipose tissue hormones regulating energy balance and glucose metabolism in diabetic db/db mice (BKS.Cg-Dock7Lepr/J). The body composition parameters in mice aged 8, 12, and 16 weeks were assessed by magnetic resonance imaging.
View Article and Find Full Text PDFCorrection to Comparative Study of Toxicity of Alkoxyamines In Vitro and In Vivo.
Bull Exp Biol Med
May 2018
N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia.
The author name M. V. Edeeva should read M.
View Article and Find Full Text PDFComparative Study of Toxicity of Alkoxyamines In Vitro and In Vivo.
Bull Exp Biol Med
November 2017
N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia.
Effect of alkoxyamines on normal and tumor cells was studied in vitro and in vivo. In vitro experiments showed that alkoxyamines produce a dose-dependent toxic effect on cells of human breast tumor MCF7 line. Transplantation of Krebs-2 ascites carcinoma cells preincubated with alkoxyamines to mice did not induce tumor growth.
View Article and Find Full Text PDFHigh Antimetastatic Activity of Platin Liposomal Form after Lyophilization and Storage.
Bull Exp Biol Med
July 2017
Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia.
Antimetastatic activity of Platin in lyophilized liposomes stored for 7 years after fabrication was evaluated. The main flaw of liposomes as vehicles for drug delivery to the tumors is their high affinity for the liver, which accumulates a great amount thereof. This property of liposomes can be used for adjuvant therapy of operable primary tumors metastasizing to the liver.
View Article and Find Full Text PDF[Polymorphism of the HFE gene associated with hereditary hemochromatosis in populations of Russia].
Genetika
July 2003
Research Institute of Cytology and Genetics, Russian Academy of Sciences, Novosibirsk, 630090 Russia.
Expression of hereditary hemochromatosis as well as predisposition to iron overload syndrome and sporadic porphyria cutanea tarda are currently believed to be associated with the inheritance of certain allelic variants of the HFE gene. Allele frequencies of the C282Y (845A) and H63D (187G) mutations in the HFE gene in human populations of different races are remarkably different, and the prevalence of the S65C (193T) mutation is still poorly studied. In the present study we estimated allele frequencies of HFE mutations in Russians and in a number of Siberian ethnic indigenous populations.
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