3 results match your criteria: "Research Institute for the Biology of Farm Animals (FBN) Dummerstorf[Affiliation]"
Expression of microRNAs is not related to increased expression of ZDHHC9 in hind leg muscles of splay leg piglets.
Mol Cell Probes
February 2010
Research Institute for the Biology of Farm Animals (FBN) Dummerstorf, Dummerstorf, Germany.
ZDHHC9 (zinc finger, DHHC-type containing 9) is a protein acyl transferase involved in palmitoylation of basic signaling molecules. We found ZDHHC9 expression increased in hind leg muscles of newborn splay leg piglets. In order to elucidate the background of this increased expression we determined the structure of the porcine gene, including sequence variation, and analyzed the structure and expression of microRNAs potentially targeting the gene.
View Article and Find Full Text PDFAnalysis of mRNA associated factors during bovine oocyte maturation and early embryonic development.
Mol Reprod Dev
December 2009
Research Institute for the Biology of Farm Animals (FBN) Dummerstorf, 18196 Dummerstorf, Germany.
Article Synopsis
- Translational regulation of gene expression is crucial during developmental stages, particularly when transcription is limited, as seen in the maturation of bovine oocytes and early embryos.
- The study highlights the roles of various proteins (like eIF4F components and PABPs) and kinases involved in the phosphorylation of these proteins during the transition from M II stage oocytes to early embryos, showing significant alterations in their abundance and activity.
- Overall, a decrease in poly-(A) binding proteins (PABP1 and 3) is linked to a repression of translation during the early stages of embryonic development, even as some eIF4F complexes are still forming.
Identification of candidate genes for congenital splay leg in piglets by alternative analysis of DNA microarray data.
Int J Biol Sci
June 2009
Research Institute for the Biology of Farm Animals (FBN) Dummerstorf, D-18196 Dummerstorf, Germany. maak@fbn-dummerstorf
The congenital splay leg syndrome in piglets is characterized by a temporarily impaired functionality of the hind leg muscles immediately after birth. Etiology and pathogenetic mechanisms for the disease are still not well understood. We compared genome wide gene expression of three hind leg muscles (M.
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