7 results match your criteria: "Research Institute for Microbial Diseases Osaka University Suita Japan.[Affiliation]"
Background: The process underlying Fontan pathophysiology is multifactorial and may include gut dysbiosis (GD). We investigated the presence of GD and elucidated its correlation with Fontan pathophysiology.
Methods And Results: Gut microbiomes of 155 consecutive patients with Fontan pathophysiology and 44 healthy individuals were analyzed using 16S rRNA sequencing of bacterial DNA extracted from fecal samples.
Aim: Altered gut microbiota has been proposed as one of the causes of exacerbation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2/COVID-19) from the perspective of the gut-lung axis. We aimed to evaluate gut microbiota in mechanically ventilated patients with COVID-19 prior to using antibiotics.
Methods: We retrospectively selected for enrollment COVID-19 patients who required mechanical ventilation on admission but who had not used antibiotics before admission to observe the influence of SARS-Cov-2 on gut microbiota.
Purpose: Microscopic testicular sperm extraction is the most effective treatment for NOA, but the sperm retrieval rate is low and depends on testicular maturity. However, there are limited useful tests to assess testicular maturity. Chemical exchange saturation transfer (CEST) imaging is a new magnetic resonance imaging (MRI) technique that can image the distribution of trace substances in vivo.
View Article and Find Full Text PDFHigh concentration of dopamine treatment may induce acceleration of human sperm motility.
Reprod Med Biol
October 2022
Laboratory of Animal Reproduction and Development, Graduate School of Agricultural Science Tohoku University Sendai Japan.
Purpose: In humans, catecholamines (including dopamine) have been identified in semen and fallopian tubes, while dopamine D2 receptors (D2DR) are found in the sperm midpiece region. How dopamine dose affects human sperm function and whether dopamine treatment is useful in assisted reproductive technology is unclear.
Methods: Sperm samples were obtained from patients with normal semen parameters undergoing fertility treatment.
Article Synopsis
- TULP2 is a protein mainly found in mouse testis, and its deletion has been linked to issues with sperm tail structure and male infertility in knockout mice.
- The study involved examining male fertility and sperm characteristics of knockout mice created using conventional methods and CRISPR/Cas9 technology, while also employing advanced microscopy techniques for detailed observation.
- Findings indicated that the absence of TULP2 resulted in infertility and abnormal sperm tail morphology, suggesting TULP2's critical role in the formation or maintenance of specific sperm structures, particularly outer dense fibers.
Background: A mixture of spermatozoa and accessory gland secretions (from seminal vesicles, prostates, and coagulating glands) is ejaculated into the female reproductive tract at copulation. However, the physiological function of accessory glands on male fecundity remains unclear.
Methods: Publications regarding the physiological functions of male accessory glands were summarized.
Background: Reproductive research is quintessential in understanding not only the cause of infertility, but also for creating family planning tools. The knockout (KO) system approach is conducive to discovering genes that are essential for fertility in mice. However, in vivo research has been limited due to its high cost and length of time needed to establish KO mice.
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