31 results match your criteria: "Research Institute for Development IRD[Affiliation]"

Epidemiology of envenomations by terrestrial venomous animals in Brazil based on case reporting: from obvious facts to contingencies.

J Venom Anim Toxins Incl Trop Dis

June 2015

UMR 216, Mother and Child Facing Tropical Diseases, Research Institute for Development (IRD), 08 BP 841 Cotonou, Benin ; School of Pharmacy, Paris Descartes University, Sorbonne, Paris Cité, France.

Article Synopsis
  • Envenomation from venomous animals like snakes and scorpions is a significant public health problem in tropical countries, highlighted by a study on Brazil's compulsory reporting system for these cases.
  • Over a 12-year period, Brazil recorded over 1.1 million envenomation incidents and nearly 2,700 deaths, with notable regional differences in incidence and mortality rates.
  • The study suggests that mandatory reporting enhances envenomation management but recommends ongoing local research to tailor prevention and treatment strategies based on specific accident circumstances.
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Background: Better treatments are urgently needed for the management of Ebola virus epidemics in Equatorial Africa.

Methods: We conducted a systematic review of the literature on the use of passive immunotherapy for the treatment or prevention of Ebola virus disease. We placed findings from this review into the context of passive immunotherapy currently used for venom-induced disease, and recent improvements in manufacturing of polyvalent antivenom products.

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Rift Valley fever (RVF) is a vector-borne zoonotic disease that causes high morbidity and mortality in ruminants. In 2008-2009, a RVF outbreak affected the whole Madagascar island, including the Anjozorobe district located in Madagascar highlands. An entomological survey showed the absence of Aedes among the potential RVF virus (RVFV) vector species identified in this area, and an overall low abundance of mosquitoes due to unfavorable climatic conditions during winter.

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Objectives: To assess long-term adherence of the first HIV-1 patients receiving highly active antiretroviral therapy (HAART) in Senegal, and to identify the main determinants of adherence.

Methods: The first 180 patients enrolled in the Senegalese HAART initiative between August 1998 and April 2001 followed up for at least 30 days were eligible. Adherence was assessed monthly at each drug dispensation between November 1999 and November 2006 by a pharmacist using a pill count completed by a questionnaire.

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Objectives: To evaluate survival and investigate causes of death among HIV-1 infected adults receiving HAART in Senegal.

Design: An observational prospective cohort.

Methods: Mortality was assessed in the first patients enrolled between August 1998 and April 2002 in the Senegalese antiretroviral drug access initiative.

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