43 results match your criteria: "Research Institute Puerta de Hierro-Segovia de Arana.[Affiliation]"

Objective: To evaluate the impact of the different types of neoplasms and lineages on Sjögren syndrome (SjS) patient mortality.

Methods: Medical records review study based on the Spanish Hospital Discharge Database and the International Classification of Diseases, Tenth Revision, Clinical Modification coding list. The neoplasm-related deaths in SjS patients with the general population during the period 2016-2019 were compared.

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Gut Dysbiosis and Its Role in the Anemia of Chronic Kidney Disease.

Toxins (Basel)

November 2024

Anemia Working Group of the Spanish Society of Nephrology, 39008 Santander, Spain.

Article Synopsis
  • Gut dysbiosis in chronic kidney disease (CKD) has been linked to anemia due to factors like increased uremic toxins, inflammation from gut barrier issues, and reduced production of beneficial short-chain fatty acids (SCFAs).
  • Addressing gut dysbiosis can help manage anemia in CKD patients by reducing harmful medications, incorporating dietary changes, and using prebiotics or probiotics to enhance beneficial gut bacteria.
  • Improving gut health in CKD not only alleviates anemia symptoms but can also boost the effectiveness of treatments like erythropoiesis-stimulating agents (ESAs) in patients unresponsive to standard therapies.
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Efficacy and safety of antistaphylococcal penicillin or cephazolin-based combinations versus monotherapy for methicillin-susceptible Staphylococcus aureus infective endocarditis: A propensity score analysis of nationwide prospective cohort.

J Infect

December 2024

Infectious Diseases Unit, Internal Medicine Department, University Hospital Puerta de Hierro, Majadahonda, Madrid, Spain; Research Institute Puerta de Hierro-Segovia de Arana (IDIPHSA), Majadahonda, Spain; Department of Medicine, University Autonoma of Madrid, Madrid, Spain.

Objectives: We aimed to evaluate the usefulness of antistaphylococcal penicillin (ASP) or cephazolin-based combinations versus monotherapy in patients with native-valve infective endocarditis (IE) caused by methicillin-susceptible Staphylococcus aureus (MSSA).

Methods: Post-hoc analysis of a multicentre prospective cohort. We include patients from 2008 to 2022 with definite native-valve, left-side IE due to MSSA treated primarily with ASP/cephazolin.

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Objective: Evaluating the impact of solid organ neoplasms (SON) and hematological neoplasms (HN) on mortality among RA patients in a nationwide study.

Methods: A retrospective, observational comparison of SON and HN-related deaths in RA patients and the general Spanish population was conducted (Spanish Hospital Discharge Database). Binary logistic regression analyzed the impact of RA on mortality risk from each neoplasm.

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Increased incidence and mortality from Listeria monocytogenes infection in Spain.

Int J Infect Dis

August 2024

UNIR Health Sciences School and Medical Center, Madrid, Spain; Internal Medicine Department, Health Research Institute Puerta de Hierro-Segovia de Arana (IDIPHIM), Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, Spain. Electronic address:

Objectives: Listeria monocytogenes (LM) is a health threat worldwide given its high mortality and the growing of high-risk susceptible populations.

Methods: All hospitalizations with a diagnosis of LM in the National Registry of Hospital Discharges were examined in Spain from 2000 to 2021.

Results: A total of 8152 hospital admissions with LM were identified.

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Trends in epidemiology, surgical management, and prognosis of infective endocarditis during the XXI century in Spain: A population-based nationwide study.

J Infect Public Health

May 2024

Infectious Diseases Unit, Department of Internal Medicine, University Hospital Puerta de Hierro, Majadahonda, Majadahonda, Spain; Research Institute Puerta de Hierro-Segovia de Arana (IDIPHSA). Majadahonda, Spain; Autónoma University of Madrid, Spain.

Background: Few population-based studies have evaluated the epidemiology of infective endocarditis (IE). Changes in population demographics and guidelines on IE may have affected both the incidence and outcomes of IE. Therefore, the aim of our study is to provide contemporary population-based epidemiological data of IE in Spain.

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Background: This study aimed to validate the role of the D-dimer to lymphocyte ratio (DLR) for mortality prediction in a large national cohort of hospitalized coronavirus disease 2019 (COVID-19) patients.

Methods: A retrospective, multicenter, observational study that included hospitalized patients due to SARS-CoV-2 infection in Spain was conducted from March 2020 to March 2022. All biomarkers and laboratory indices analyzed were measured once at admission.

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Background: Several aspects of the occurrence and management of mycotic aneurysm (MA) in patients with infective endocarditis (IE) have not been studied.

Objectives: To determine the incidence and factors associated with MA presence and rupture and to assess the evolution of those initially unruptured MA.

Methods: Prospective multicenter cohort including all patients with definite IE between January 2008 and December 2020.

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Article Synopsis
  • Sarcoidosis patients have a significantly lower survival rate than the general population, with higher mortality linked to hematological neoplasms (HN) and lymphomas.
  • The study compared in-hospital deaths from HN between sarcoidosis patients and the general population in Spain, revealing that sarcoidosis patients died at a younger age and had a higher risk of death from non-Hodgkin lymphoma and other HN types.
  • The findings highlight the need for targeted strategies to manage the increased mortality risk among sarcoidosis patients, particularly regarding HN and lymphoma types.
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Background: Attention deficit hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder in childhood and adolescence, with a prevalence of 5% and associated difficulties and worse prognosis if undetected. Multimodal treatment is the treatment of choice. However, sometimes treatment can be insufficient or have drawbacks.

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Introduction: Antivirals and monoclonal antibodies lower the risk of progression in immunocompromised patients. However, combination therapy with both types of agents has not been studied.

Patients And Methods: This was a single-centre, prospective, cohort study.

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Speer allergic tension-fatigue syndrome (SATFS) is a classic allergy syndrome characterized by allergy-like symptoms, muscle tension, headaches, chronic fatigue, and other particular behaviors that were initially described in the fifties. The particular behaviors displayed include symptoms such as hyperkinesis, hyperesthesia (i.e.

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Vertebral osteomyelitis after spine instrumentation surgery: risk factors and management.

J Hosp Infect

October 2023

Infectious Diseases Department, Hospital Universitari de Bellvitge, IDIBELL, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain; Study Group on Osteoarticular Infections of the Spanish Society of Clinical Microbiology and Infectious Diseases (GEIO-SEIMC), Spain; Centro de Investigación Biomédica en Red en Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain. Electronic address:

Background: Vertebral osteomyelitis after spine instrumentation surgery (pVOM) is a rare complication. Most cases of infection occur early after surgery that involve skin and soft tissue and can be managed with debridement, antibiotics, and implant retention (DAIR).

Aim: To identify pVOM risk factors and evaluate management strategies.

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Aim: To identify the presence of variability in the evaluation of case studies prepared by nursing students during their primary care rotations based on the existing evaluation rubric. To explore the difficulties experienced by link lecturers and students in preparing and evaluating case studies.

Design: A mixed methods study.

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Prevalence and impact of cerebrovascular risk factors in patients with giant cell arteritis: An observational study from the Spanish national registry.

Med Clin (Barc)

July 2023

Internal Medicine Department, Health Research Institute Puerta de Hierro-Segovia de Arana (IDIPHIM) Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain; UNIR Health Sciences School, Madrid, Spain. Electronic address:

Objective: To assess the prevalence and impact of cerebrovascular risk factors (CRF) on cerebrovascular events (CVE) in patients with giant cell arteritis (GCA).

Methods: Analysis of the patients diagnosed with GCA identified in the Spanish Hospital Discharge Database between 2016 and 2018.

Results: 8,474 hospital admissions from patients diagnosed with GCA were identified.

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Bullying is a risk factor for the physical and mental health of adolescents. The advent of new technologies has resulted in a brand-new type of bullying, cyberbullying (CB). The co-occurring effects of cyberbullying and traditional bullying(TB) forms of bullying on adolescent mental health are unclear.

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Current Issues in Fungal Infections and COVID-19.

J Fungi (Basel)

October 2022

First Department of Critical Care Medicine and Pulmonary Services, Evangelismos Hospital, National and Kapodistrian University of Athens Medical School, 11527 Athens, Greece.

The COVID-19 pandemic has brought up a new host for fungal invasive infections [...

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Symptoms of Attention Deficit Hyperactivity Disorder (ADHD) include excessive activity, difficulty sustaining attention, and inability to act in a reflective manner. Early diagnosis and treatment of ADHD is key but may be influenced by the observation and communication skills of caregivers, and the experience of the medical professional. Attempts to obtain additional measures to support the medical diagnosis, such as reaction time when performing a task, can be found in the literature.

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Purpose: To evaluate Red blood cell distribution width (RDW) as a sepsis prognostic biomarker.

Methods: 203 septic patients admitted to the ICU. Analysis of RDW dynamics, hospital mortality discrimination ability and the added value when incorporated to the SOFA, LODS, SAPS-II and APACHE-II scores using the AUC-ROC.

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Objectives: To determine the burden and impact of cardiovascular risk factors (CRF) in antiphospholipid syndrome (APS) patients.

Methods: Analysis of the patients diagnosed with APS identified in the Spanish Hospital Discharge Database between 2016 and 2017. We analysed the admissions due to arterial (ATE) and venous thromboembolic events (VTE) and evaluated the incidence and the attributed risk of each CRF.

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Article Synopsis
  • A study was conducted comparing the pain and anxiety levels experienced during two fertility tests: hysterosalpingo-foam sonography (HyFoSy) and hysterosalpingography (HSG), among 210 women trying to conceive.
  • Results showed that women undergoing HyFoSy reported significantly lower pain (median score of 2) and anxiety levels compared to those who had HSG (median pain score of 5 and higher anxiety scores).
  • The findings suggest that HyFoSy is a more tolerable option for women facing fertility challenges, providing both less pain and reduced anxiety during the procedure.
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