Influence of H. pylori infection and eradication on p53, c-erbB-2 and Ki-67 in gastric mucosa.

Background/aims: To evaluate the expression of antigens c-erbB-2, p53, and Ki-67 in gastric biopsy, bacteria density and urease activity in two groups of patients with chronic gastritis separated on the basis of the success or failure of H. pylori eradication.

Methodology: Sixty-five patients with chronic gastritis were split in two groups (n=45/20) related to response to the therapy.

Effects of oxprenolol treatment on pseudocholinesterase and lipids in rats.

The effect of chronic treatment with the non-selective beta-blocker oxprenolol (CAS 6452-71-7) administered orally in two different doses (15 or 30 mg/kg/day for 6, 10 and 12 weeks) on plasma cholinesterase (PChE) activity and on the plasma level of triglyceride and total cholesterol were studied in normal rats. In all treated groups a significant increase (approximately 27-51%) of PChE activity was obtained (p < 0.05 vs.