13 results match your criteria: "Research Institute Amsterdam Cardiovascular Sciences[Affiliation]"

Background: Patients with kidney failure undergoing dialysis often suffer from anemia. Iron deficiency, along with a shortage in erythropoietin, is a common cause. Peritoneal dialysis (PD) patients may have a different iron metabolism compared to hemodialysis (HD) patients.

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Article Synopsis
  • Pruritus, or itchiness, is commonly experienced by dialysis patients and linked to lower quality of life and sleep issues, but the reasons behind it and effective treatments are still not well understood.
  • A study of 1,438 new dialysis patients showed that around 50.5% to 56.6% experienced pruritus within the first year, with 35% having persistent itching and only a small percentage receiving treatment; emollients even worsened the severity.
  • Overall, pruritus negatively impacted both physical and mental health-related quality of life, indicating a significant need for better awareness and development of treatment options for affected patients.
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Kidney protective mechanisms of SGLT2 inhibitors: evidence for a hemodynamic effect.

Kidney Int

June 2024

Diabetes Center, Department of Internal Medicine, Amsterdam University Medical Centers, Amsterdam, the Netherlands; Research Institute Amsterdam Cardiovascular Sciences, Vrije Universiteit University, Amsterdam, the Netherlands.

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Rationale & Objective: Almost all patients who receive dialysis experience polypharmacy, but little is known about their experiences with medication or perceptions toward it. In this qualitative study, we aimed to gain insight into dialysis patients' experiences with polypharmacy, the ways they integrate their medication into their daily lives, and the ways it affects their quality of life.

Study Design: Qualitative study using semistructured interviews.

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Article Synopsis
  • The study investigates the usage and impact of Dutch patient decision aids like Three Good Questions and the Dutch Kidney Guide in kidney failure treatment education by healthcare professionals.
  • It finds that while over half of the healthcare professionals implemented shared decision-making tools, only specific hospitals had a significantly higher application of these aids, leading to better patient satisfaction scores.
  • Despite a training workshop aimed at improving shared decision-making practices, patients did not report any change in their perceived experience of shared decision-making.
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  • The study aimed to explore the connection between patient comorbidities and the choice of dialysis method in the Netherlands, where home dialysis rates have been decreasing over recent years.
  • Researchers analyzed data from the DOMESTICO cohort study, which included 1,358 patients starting dialysis, using the Charlson comorbidity index to gauge the impact of comorbidities on the likelihood of patients receiving home dialysis.
  • Findings revealed that while higher comorbidity scores initially suggested a lower probability of receiving home dialysis, this association disappeared after adjusting for other factors like age and body mass index, indicating that other centre-specific characteristics may be influencing dialysis modality choices.
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Background: Technique survival is a core outcome for peritoneal dialysis (PD), according to Standardized Outcomes in Nephrology-Peritoneal Dialysis. This study aimed to identify modifiable causes and risk factors of technique failure in a large Dutch cohort using standardised definitions.

Methods: Patients who participated in the retrospective Dutch nOcturnal and hoME dialysis Study To Improve Clinical Outcomes cohort study and started PD between 2012 and 2016 were included and followed until 1 January 2017.

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Background: Dialysis is associated with frequent hospitalisations. Studies comparing hospitalisations between peritoneal dialysis (PD) and haemodialysis (HD) report conflicting results and mostly analyse data of patients that remain on their initial dialysis modality. This cohort study compares hospitalisations between PD and HD patients taking into account transitions between modalities.

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Background: In Europe, the number of elderly end-stage kidney disease patients is increasing. Few of those patients receive peritoneal dialysis (PD), as many cannot perform PD autonomously. Assisted PD programmes are available in most European countries, but the percentage of patients receiving assisted PD varies considerably.

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Impact of Polypharmacy on Health-Related Quality of Life in Dialysis Patients.

Am J Nephrol

March 2022

Department of Nephrology, Amsterdam UMC, Research Institute Amsterdam Cardiovascular Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

Introduction: Dialysis patients are often prescribed a large number of medications to improve metabolic control and manage coexisting comorbidities. However, some studies suggest that a large number of medications could also detrimentally affect patients' health-related quality of life (HRQoL). Therefore, this study aims to provide insight in the association between the number of types of medications and HRQoL in dialysis patients.

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Background: Although the number of patients with end-stage kidney disease is growing, the number of patients who perform dialysis at home has decreased during the past two decades. The aim of this study was to explore time trends in the use of home dialysis in the Netherlands.

Methods: Dialysis episodes of patients who started dialysis treatment were studied using Dutch registry data (RENINE).

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Background: Most pre-dialysis patients are medically eligible for home dialysis, and home dialysis has several advantages over incentre dialysis. However, accurately selecting patients for home dialysis appears to be difficult, since uptake of home dialysis remains low. The aim of this study was to investigate which medical or psychosocial elements contribute most to the selection of patients eligible for home dialysis.

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Background: Studies have shown increased anxiety, depression, and stress levels among different populations during the coronavirus disease 2019 (COVID-19) pandemic. However, the impact of the pandemic on the mental health of dialysis patients remains unknown. The aim of this study was to investigate the mental health of dialysis patients during the COVID-19 pandemic compared to the period preceding the pandemic.

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