1 results match your criteria: "Research Center of the Hospital Center of the University of Montreal-Notre-Dame Hospital[Affiliation]"
Cytotoxic NKG2C+ CD4 T cells target oligodendrocytes in multiple sclerosis.
J Immunol
March 2013
Department of Medicine, Research Center of the Hospital Center of the University of Montreal-Notre-Dame Hospital, Montreal, Quebec H2L 4M1, Canada;
The mechanisms whereby immune cells infiltrating the CNS in multiple sclerosis patients contribute to tissue injury remain to be defined. CD4 T cells are key players of this inflammatory response. Myelin-specific CD4 T cells expressing CD56, a surrogate marker of NK cells, were shown to be cytotoxic to human oligodendrocytes.
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