Pathogenic role of melatonin in sleep disorders in menopausal women.

The data on circadian rhythms of melatonin secretion in women of perimenopausal (n=39) and postmenopausal (n=52) age are presented. Each group was divided into control (without sleep disorders) and main group (with sleep disorders). The saliva was collected 4 times a day (6.

Antioxidant potential of the blood in men with obstructive sleep breathing disorders.

We studied the state of the LPO-antioxidant defense system in men aged from 46 to 55 years. The main group included patients with obstructive sleep breathing disorders. The state of the antioxidant defense system was assessed by measuring the blood levels of LPO substrates with conjugated double bonds, conjugated dienes, ketodienes and conjugated trienes, MDA, retinol, α-tocopherol, reduced and oxidized glutathione, SOD activity, and the level of total antioxidant activity of blood.

Interhemispheric interaction in children with autonomic dysfunction of the sinus node.

Electroencephalography was performed in 7-8- and 9-10-year-old pupils. Control group consisted of healthy children; experimental group consisted of children without signs of grade IV and V sinus arrhythmia at the age of 7-8 years, but with grade IV and V sinus arrhythmia at the age of 9-10 years. In primary school-aged children (7-8 years), manifestation of marked sinus arrhythmia is associated with disturbances in age-specific dynamics of interhemispheric interaction and with the formation, at the initial stage, of a rigid integrated system primarily due to functional intrahemispheric connections, the major contribution being made by the posterior associative cortical areas.