334 results match your criteria: "Research Center for Medicine and Social Development[Affiliation]"

Article Synopsis
  • RSA is linked to metabolic imbalances at the maternal-fetal interface, especially concerning essential fatty acids and oxylipins, which may contribute to the risk of spontaneous abortion.
  • Research involved analyzing samples from women experiencing spontaneous abortion and those with normal pregnancies, measuring fatty acid levels and enzyme expressions using advanced techniques like GC-MS and LC-MS.
  • Findings showed that women with recurrent spontaneous abortion had higher omega-6 fatty acid levels in their plasma and chorionic villi but lower levels in the decidua, suggesting a possible dysregulation of fatty acid transport affecting pregnancy outcomes.
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Association between ambient temperatures and cardiovascular disease: A time series analysis using emergency ambulance dispatches in Chongqing, China, 2019-2021.

Health Place

December 2024

School of Public Health, Research Center for Medicine and Social Development, Innovation Center for Social Risk Governance in Health, Research Center for Public Health Security, Chongqing Medical University, No.61 Middle University Town Road, Shapingba District, Chongqing, 400016, China. Electronic address:

Background: Cardiovascular disease (CVD) is one of the leading causes of death globally. Yet, further research is required into the relationship between CVD and extreme environmental temperatures. This study aims to explore the association between the incidence of CVD and extreme temperatures, and also to identify susceptible subgroups within the population.

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Hypertension and 28-day mortality in sepsis patients: An observational and mendelian randomization study.

Heart Lung

December 2024

Department of Epidemiology and Health Statistics, School of Public Health, Chongqing Medical University, Chongqing, China; Research Center for Medicine and Social Development, Chongqing, China; Collaborative Innovation Center of Social Risks Governance in Health, Chongqing Medical University, Chongqing, China; Research Center for Public Health Security, Chongqing Medical University, Chongqing, China. Electronic address:

Background: Predicting and reducing the 28-day mortality in sepsis remains a challenge in this research field.

Objective: This study aimed to explore the association between hypertension and 28-day mortality in sepsis.

Methods: This study is a cross-sectional approach with Mendelian Randomization (MR).

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Background: Preexposure prophylaxis (PrEP) is an effective strategy to reduce the risk of HIV infection. However, the efficacy of PrEP is highly dependent on adherence. Meanwhile, adherence changes over time, making it difficult to manage effectively.

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Article Synopsis
  • Excessive consumption of oil and salt is a significant public health concern in China, particularly in Southwestern regions where intakes often exceed WHO guidelines.
  • A study involving over 7,300 participants from Sichuan, Chongqing, Yunnan, and Guizhou investigated their knowledge, attitudes, and practices (KAP) towards oil and salt intake using surveys and statistical models.
  • Results indicated that residents in Guizhou had poor KAP scores, with urban areas showing better performance; factors influencing KAP included education level, taste preferences, ethnicity, and the presence of chronic diseases like diabetes.
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Predicting the Risk of Loneliness in Children and Adolescents: A Machine Learning Study.

Behav Sci (Basel)

October 2024

Research Center for Medicine and Social Development, School of Public Health, Chongqing Medical University, No. 1 Yixueyuan Road, Yuzhong District, Chongqing 400016, China.

Background: Loneliness is increasingly emerging as a significant public health problem in children and adolescents. Predicting loneliness and finding its risk factors in children and adolescents is lacking and necessary, and would greatly help determine intervention actions.

Objective: This study aimed to find appropriate machine learning techniques to predict loneliness and its associated risk factors among schoolchildren.

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Urinary metals are associated with obesity in U.S. children and adolescents: A cross-sectional study.

Nutr Res

December 2024

School of Public Health, Research Center for Medicine and Social Development, Innovation Center for Social Risk Governance in Health, Research Center for Public Health Security, Chongqing Medical University, Chongqing, China. Electronic address:

Heavy metals are pervasive in the environment, and exposure to these metals may contribute to obesity in children and adolescents. We hypothesized that metal exposures are associated with obesity in children and adolescents. Data were drawn from children and adolescents aged 6 to 19 years from the 2007 to 2018 National Health and Nutrition Examination Survey.

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Background: Patient satisfaction is a powerful predictor of an individual's mental health, according to previous research. However, there has not been a thorough study on the relationship between depression and overall medical service satisfaction (OMSS) in middle-aged and older adults. Moreover, little is known about how different Internet-using patterns affect this relationship.

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Objectives: We aimed to assess the influence of psychosocial profiles on dietary behaviors among school-aged adolescents in China.

Methods: A cross-sectional study was conducted involving 7,862 adolescents from 100 schools in Shandong, China. Psychosocial profiles and dietary behaviors were assessed using the Junior High School Students' Psychosocial Profiles Questionnaire (JPPQ) and the Chinese Diet Quality Questionnaire (DQQ), respectively.

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Objective: To explore the correlation between different types of vegetable and fruit intake and cognitive function among the older adults in Chongqing, China, and to provide a scientific basis for developing efficient lifestyle interventions for the prevention of Mild Cognitive Impairment (MCI).

Method: Approximately 728 older adults in urban and rural areas of Chongqing were surveyed using face-to-face questionnaires. Cognitive function was assessed with the Montreal Cognitive Assessment-Basic (MoCA-B) scale, and the vegetable and fruit intake groups were investigated with the Simple Food Frequency Counting Survey Scale.

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Background: Patients with heart failure have a high rate of health literacy deficiency, and their hospital readmission is a great burden. Whether health literacy affects hospital readmission remains controversial.

Objective: To investigate the impact of health literacy on hospital readmission among heart failure patients.

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Article Synopsis
  • The study looks at how being nearsighted (myopic) affects junior high school students' school performance and feelings of sadness (depression).
  • Researchers tested 1,752 students and found that a lot of the nearsighted students also struggled with putting off their schoolwork and feeling depressed.
  • The results showed that nearsighted students were at a much higher risk for having these problems compared to students who could see well.
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Article Synopsis
  • - The study investigates how life satisfaction impacts learning burnout in medical postgraduate students, considering the roles of mobile phone addiction and psychological capital.
  • - Using data from 628 students, researchers found that higher life satisfaction and psychological capital are linked to lower learning burnout, while mobile phone addiction contributes to increased burnout.
  • - Findings suggest that both mobile phone addiction and psychological capital significantly mediate the relationship between life satisfaction and learning burnout, emphasizing the importance of mental well-being in academic environments.
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Objective: To explore the impact of intergenerational connections on cognitive function in middle-aged and older adults (45-60 years and over 60 years, respectively) and analyze the urban-rural and sex differences in the effects of intergenerational connections on cognitive function.

Method: Based on China Health and Retirement Longitudinal Study data (CHARLS), this study conducted ID matching for four waves of data from 2011, 2013, 2015, and 2018. Cognitive function was measured via Telephone Interview for Cognitive Status-modified (TICS-m), word recall, and imitation drawing.

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Article Synopsis
  • Men who have sex with men (MSM) are at high risk for HIV, and consistent use of pre-exposure prophylaxis (PrEP) is crucial for its effectiveness.
  • A study conducted in Western China aimed to develop a machine learning web app to predict PrEP adherence among MSM, analyzing data from 747 participants.
  • The research identified 11 key factors influencing adherence, such as partner attitudes and self-efficacy, and resulted in a successful web application that helps identify individuals at risk of nonadherence, enhancing overall prevention strategies.
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Introduction: The efficacy of pre-exposure prophylaxis (PrEP) is highly dependent on adherence, and adherence behavior is influenced by motivation. The aim of this study was to explore the longitudinal relationship between PrEP motivation and change in adherence among men who have sex with men (MSM) in Western China.

Methods: From November 2019 to June 2021, we conducted a PrEP prospective cohort study.

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Clinical nutritionists are responsible for nutritional therapy in clinical practice, which significantly enhances patients' nutritional status. This study aims to develop and validate a competency evaluation scale to effectively assess the abilities of clinical nutritionists. The competency evaluation scale for clinical nutritionists was developed based on the iceberg model, utilizing literature review, semi-structured interviews, and the Delphi method.

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Introduction: To date, the reliability of pubertal development self-assessment tools is questioned, and very few studies have explored the comparison between these tools in longitudinal studies. Hence, this study aimed to examine the reliability of pubertal development self-assessment using realistic color images (RCIs) and the Pubertal Development Scale (PDS) in a longitudinal cohort study.

Methods: Our longitudinal study recruited 1,429 participants (695 boys and 734 girls), aged 5.

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Childhood exposure to polycyclic aromatic hydrocarbons is associated with emotional and behavioral problems in adolescence: a longitudinal study in China.

Int Arch Occup Environ Health

October 2024

School of Public Health, Research Center for Medicine and Social Development, Chongqing Medical University, No. 61, University Town Middle Road, Shapingba District, Chongqing, 400016, China.

Purpose: The aim of this study was to investigate the relationship between childhood polycyclic aromatic hydrocarbon (PAH) exposure and emotional and behavioral problems in adolescence.

Methods: Participants included 998 school-age children aged 7-12 years (514 girls and 484 boys). Metabolite concentrations of four PAHs (1-hydroxypyrene [1-OHPyr], 2-hydroxynaphthalene [2-OHNap], 2-hydroxyfluorine [2-OHFlu], and 9-hydroxyphenanthrene [9-OHPhe]) were measured in urine samples at baseline (Dec 2014-Dec 2015).

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Article Synopsis
  • Lung cancer (LC) is the leading cause of cancer-related deaths in China, with the study analyzing its trends and risk factors from 1990 to 2019 and projecting the next 41 years.
  • Data collected on lung cancer incidence, deaths, and disability-adjusted life years (DALYs) revealed that all three metrics increased over the studied period, with specific risk factors like ambient particulate matter pollution showing significant rises while some factors like household air pollution decreased.
  • An autoregressive integrated moving average (ARIMA) model predicts continued increases in mortality and DALYs rates due to lung cancer, suggesting an ongoing escalation in the disease's burden in China.
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Article Synopsis
  • The study focuses on the heterogeneity of the tumor microenvironment (TME) in melanoma and how it affects responses to immune checkpoint inhibitors (ICIs).
  • Researchers analyzed single-cell sequencing data from melanoma patients using specialized algorithms to better understand microenvironment cell characteristics.
  • They identified various cell types, finding that a higher proportion of B cells correlates with better patient prognosis, while increased macrophages are found in non-responsive patients, ultimately developing a predictive model based on nine gene features for ICI response.
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Background: Time-restricted eating (TRE), a popular form of intermittent fasting, has shown benefits for improving metabolic diseases and cardiometabolic health. However, the effect of TRE in the regulation of blood pressure in primary hypertension remains unclear.

Methods: A 6-week randomized controlled trial was conducted, in which a total of 74 stage 1 primary hypertensive patients without high-risk were randomly assigned to Dietary Approaches to Stop Hypertension (DASH) group (n = 37) or DASH + TRE group (n = 37).

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Psychosocial Stress Trajectories are Associated with Puberty Timing: Findings from A 7-year Cohort in Chongqing, China.

J Clin Endocrinol Metab

June 2024

Research Center for Environment and Human Health, Research Center for Medicine and Social Development, School of Public Health, Chongqing Medical University, Chongqing, China.

Objectives: To evaluate the association between psychosocial stress (PS) trajectories and pubertal outcomes of girls and boys in a Chinese cohort (2015-2022).

Methods: Pubertal outcomes of 732 girls and 688 boys were physically examined every 6 months. Stressful life events were repeatedly assessed 7 times.

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Purpose: High levels of depression are common among men who have sex with men (MSM) in China, and there is limited research on the relationship between MSM stigma and depression. Guided by the psychological mediation framework, to explore the relationship between stigma and depression among MSM and how positive sexual identity plays a role in it, we tested this model whether: 1) enacted MSM stigma, perceived MSM stigma, and positive sexual identity are associated with depression; 2) their effects on depression are mediated through resilient coping and social support; and 3) perceived MSM stigma is a mediator of the effects of enacted MSM stigma and positive sexual identity on depression.

Methods: We conducted mediation analyses using structural equation modeling (SEM) on data from a cross-sectional survey conducted among 1014 MSM recruited using a non-probability sampling method in December 2022.

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Unhealthy lifestyles among adolescents are reaching alarming levels and have become a major public health problem. This study aimed to assess the relationship between sleep time, physical activity (PA) time, screen time (ST), and nutritional literacy (NL). This cross-sectional online study involving adolescents aged 10-18 years was conducted in September 2020 in 239 schools in Chongqing, China.

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