534 results match your criteria: "Research Center for Artificial Intelligence[Affiliation]"
Asia Pac J Oncol Nurs
May 2024
School of Health Care Administration, Taipei Medical University, Taipei, Taiwan.
[This corrects the article DOI: 10.1016/j.apjon.
View Article and Find Full Text PDFCureus
April 2024
International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, TWN.
Squamous cell carcinoma (SCC) is the second most common type of skin cancer. As ultraviolet exposure represents an important risk factor, SCC commonly occurs on the face, lips, scalp, hands, and heels. The foot is an unusual location to manifest SCC.
View Article and Find Full Text PDFPLoS One
May 2024
Chair of Physics Education, Ludwig-Maximilians-Universität München (LMU Munich), Munich, Germany.
Classical statistical analysis of data can be complemented or replaced with data analysis based on machine learning. However, in certain disciplines, such as education research, studies are frequently limited to small datasets, which raises several questions regarding biases and coincidentally positive results. In this study, we present a refined approach for evaluating the performance of a binary classification based on machine learning for small datasets.
View Article and Find Full Text PDFLangmuir
June 2024
State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, People's Republic of China.
The inclusion of sacrificial hydrogen bonds is crucial for advancing high-performance rubber materials. However, the molecular mechanisms governing the impact of these bonds on material properties remain unclear, hindering progress in advanced rubber material research. This study employed all-atom molecular dynamics simulations to thoroughly investigate how hydrogen bonds affect the structure, dynamics, mechanics, and linear viscoelasticity of rubber materials.
View Article and Find Full Text PDFComput Biol Med
June 2024
Department of Computer Science, Rhineland-Palatinate Technical University of Kaiserslautern-Landau, Kaiserslautern, 67663, Germany; German Research Center for Artificial Intelligence GmbH, Kaiserslautern, 67663, Germany.
Anticancer peptides (ACPs) key properties including bioactivity, high efficacy, low toxicity, and lack of drug resistance make them ideal candidates for cancer therapies. To deeply explore the potential of ACPs and accelerate development of cancer therapies, although 53 Artificial Intelligence supported computational predictors have been developed for ACPs and non ACPs classification but only one predictor has been developed for ACPs functional types annotations. Moreover, these predictors extract amino acids distribution patterns to transform peptides sequences into statistical vectors that are further fed to classifiers for discriminating peptides sequences and annotating peptides functional classes.
View Article and Find Full Text PDFEur Radiol Exp
May 2024
Department of Medical Imaging, Taipei Medical University Hospital, No.250, Wu Hsing Street, Taipei, Taiwan.
Background: This study investigates the potential of diffusion tensor imaging (DTI) in identifying penumbral volume (PV) compared to the standard gadolinium-required perfusion-diffusion mismatch (PDM), utilizing a stack-based ensemble machine learning (ML) approach with enhanced explainability.
Methods: Sixteen male rats were subjected to middle cerebral artery occlusion. The penumbra was identified using PDM at 30 and 90 min after occlusion.
Expert Opin Drug Metab Toxicol
July 2024
University of Information and Communication Technology, Thai Nguyen University, Thai Nguyen, Vietnam.
Introduction: This review explores the transformative impact of machine learning (ML) on carcinogenicity prediction within drug development. It discusses the historical context and recent advancements, emphasizing the significance of ML methodologies in overcoming challenges related to data interpretation, ethical considerations, and regulatory acceptance.
Areas Covered: The review comprehensively examines the integration of ML, deep learning, and diverse artificial intelligence (AI) approaches in various aspects of drug development safety assessments.
Front Microbiol
April 2024
Institute of Medical Informatics, University of Lübeck, Lübeck, Germany.
J Med Internet Res
May 2024
Department of Trauma, Hand and Reconstructive Surgery, Departments and Institutes of Surgery, Saarland University, Homburg/Saar, Germany.
Background: Monitoring of gait patterns by insoles is popular to study behavior and activity in the daily life of people and throughout the rehabilitation process of patients. Live data analyses may improve personalized prevention and treatment regimens, as well as rehabilitation. The M-shaped plantar pressure curve during the stance phase is mainly defined by the loading and unloading slope, 2 maxima, 1 minimum, as well as the force during defined periods.
View Article and Find Full Text PDFSci Rep
April 2024
Department of Computer Science, Rhineland-Palatinate Technical University of Kaiserslautern-Landau, 67663, Kaiserslautern, Germany.
Long extrachromosomal circular DNA (leccDNA) regulates several biological processes such as genomic instability, gene amplification, and oncogenesis. The identification of leccDNA holds significant importance to investigate its potential associations with cancer, autoimmune, cardiovascular, and neurological diseases. In addition, understanding these associations can provide valuable insights about disease mechanisms and potential therapeutic approaches.
View Article and Find Full Text PDFPlant Cell Rep
April 2024
State Key Laboratory of Crop Stress Adaptation and Improvement, Henan University, Kaifeng, 475004, Henan, China.
Innovatively, we consider stomatal detection as rotated object detection and provide an end-to-end, batch, rotated, real-time stomatal density and aperture size intelligent detection and identification system, RotatedeStomataNet. Stomata acts as a pathway for air and water vapor in the course of respiration, transpiration, and other gas metabolism, so the stomata phenotype is important for plant growth and development. Intelligent detection of high-throughput stoma is a key issue.
View Article and Find Full Text PDFComput Biol Med
May 2024
AIBioMed Research Group, Taipei Medical University, Taipei, 110, Taiwan; Professional Master Program in Artificial Intelligence in Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan; Research Center for Artificial Intelligence in Medicine, Taipei Medical University, Taipei, 110, Taiwan; Translational Imaging Research Center, Taipei Medical University Hospital, Taipei, 110, Taiwan. Electronic address:
Accurately predicting tumor T-cell antigen (TTCA) sequences is a crucial task in the development of cancer vaccines and immunotherapies. TTCAs derived from tumor cells, are presented to immune cells (T cells) through major histocompatibility complex (MHC), via the recognition of specific portions of their structure known as epitopes. More specifically, MHC class I introduces TTCAs to T-cell receptors (TCR) which are located on the surface of CD8+ T cells.
View Article and Find Full Text PDFHeliyon
April 2024
Department of Electrical Engineering, College of Engineering and Physics, King Fahd University of Petroleum & Minerals, Dhahran 31261, Saudi Arabia.
This paper proposes an advanced control approach to controlling a DC-DC buck converter for a proton exchange membrane (PEM) electrolyzer within the framework of a direct current (DC) microgrid. The proposed adaptive backstepping terminal sliding mode control (ABTSMC) leverages a physics-informed neural network (PINN) to accurately estimate and compensate for system uncertainty. The composite controller achieves finite-time convergence of the tracking error by combining backstepping control and terminal sliding mode control (TSMC).
View Article and Find Full Text PDFJMIR Res Protoc
April 2024
Department of Epidemiology and Preventive Medicine, Medical Sociology, University Regensburg, Regensburg, Germany.
Background: Patients after kidney transplantation eventually face the risk of graft loss with the concomitant need for dialysis or retransplantation. Choosing the right kidney replacement therapy after graft loss is an important preference-sensitive decision for kidney transplant recipients. However, the rate of conversations about treatment options after kidney graft loss has been shown to be as low as 13% in previous studies.
View Article and Find Full Text PDFLangmuir
April 2024
State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, People's Republic of China.
Polymer vitrimer is a novel material that contains dynamic covalent bonds (DCBs) allowing it to combine the desirable characteristics of both thermoplastics and thermosets. Similar to the traditional polymer nanocomposites, introducing nanoparticles into polymer vitrimer is also an effective strategy to further enhance its properties. However, a comprehensive understanding of matrix and interfacial bond exchange reactions (BERs) to tailor the properties of polymer vitrimer nanocomposites (PVNs) is still lacking.
View Article and Find Full Text PDFMicrobiol Resour Announc
April 2024
Bacterial Molecular Genetics Laboratory - LGMB, Universidad El Bosque, Bogotá, Colombia.
We report the draft genome of a clinical multi-resistant (24Kpn33) isolate, whose genome (5.7 Mbp) harbored 17 antibiotic resistance genes, including . Notably, this gene was mobilized within the IncP-6 pCOL-1 plasmid, the first genetic platform related to the acquisition and dissemination of the in .
View Article and Find Full Text PDFFront Bioeng Biotechnol
March 2024
Werner Siemens-Endowed Chair for Innovative Implant Development (Fracture Healing), Departments and Institutes of Surgery, Saarland University, Homburg, Germany.
Monitoring changes in gait during rehabilitation allows early detection of complications. Laboratory-based gait analyses proved valuable for longitudinal monitoring of lower leg fracture healing. However, continuous gait data recorded in the daily life may be superior due to a higher temporal resolution and differences in behavior.
View Article and Find Full Text PDFInt J Mol Sci
February 2024
International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
The role of the IFI6 gene has been described in several cancers, but its involvement in esophageal cancer (ESCA) remains unclear. This study aimed to identify novel prognostic indicators for ESCA-targeted therapy by investigating IFI6's expression, epigenetic mechanisms, and signaling activities. We utilized public data from the Gene Expression Omnibus (GEO) and the Cancer Genome Atlas (TCGA) to analyze IFI6's expression, clinical characteristics, gene function, pathways, and correlation with different immune cells in ESCA.
View Article and Find Full Text PDFDiagnostics (Basel)
February 2024
German Research Center for Artificial Intelligence, 23562 Lübeck, Germany.
Optical coherence tomography (OCT) is an extensively used imaging tool for disease monitoring in both age-related macular degeneration (AMD) and retinal vein occlusion (RVO). However, there is limited literature on minimum requirements of OCT settings for reliable biomarker detection. This study systematically investigates both the influence of scan size and interscan distance (ISD) on disease activity detection.
View Article and Find Full Text PDFBehav Res Methods
September 2024
Institute of Psychology, Osnabrück University, Osnabrück, Germany.
Conventionally, event-related potential (ERP) analysis relies on the researcher to identify the sensors and time points where an effect is expected. However, this approach is prone to bias and may limit the ability to detect unexpected effects or to investigate the full range of the electroencephalography (EEG) signal. Data-driven approaches circumvent this limitation, however, the multiple comparison problem and the statistical correction thereof affect both the sensitivity and specificity of the analysis.
View Article and Find Full Text PDFSci Rep
March 2024
Department of Computer Science and Engineering, University of Bologna, Bologna, Italy.
The bin packing is a well-known NP-Hard problem in the domain of artificial intelligence, posing significant challenges in finding efficient solutions. Conversely, recent advancements in quantum technologies have shown promising potential for achieving substantial computational speedup, particularly in certain problem classes, such as combinatorial optimization. In this study, we introduce QAL-BP, a novel Quadratic Unconstrained Binary Optimization (QUBO) formulation designed specifically for bin packing and suitable for quantum computation.
View Article and Find Full Text PDFFront Pharmacol
February 2024
International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Uncontrolled blood pressure is a major risk factor for cardiovascular diseases. Fixed-dose combination (FDC) therapy offers a promising approach to addressing this challenge by providing a convenient single-tablet solution that enhances the effectiveness of blood pressure control. In our systematic review, we assess the effectiveness of perindopril/amlodipine FDC in managing blood pressure.
View Article and Find Full Text PDFInt J Mol Sci
February 2024
SDAIA-KFUPM Joint Research Center for Artificial Intelligence, King Fahd University of Petroleum and Minerals (KFUPM), Dhahran 31261, Saudi Arabia.
Cancer is a leading cause of death globally. The majority of cancer cases are only diagnosed in the late stages of cancer due to the use of conventional methods. This reduces the chance of survival for cancer patients.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
February 2024
National Center for Magnetic Resonance in Wuhan, Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan 430071, People's Republic of China.
The self-assembly of proteins into curved structures plays an important role in many cellular processes. One good example of this phenomenon is observed in the septum-forming protein (SepF), which forms polymerized structures with uniform curvatures. SepF is essential for regulating the thickness of the septum during bacteria cell division.
View Article and Find Full Text PDFFront Psychiatry
February 2024
Psychotherapy Research Lab, Department of Psychology, University of Haifa, Haifa, Israel.