174 results match your criteria: "Research Center Amsterdam[Affiliation]"

Objective: The purpose of this prospective study was to evaluate the quality of the reparative cartilage during second-look needle arthroscopy following talar osteoperiostic grafting from the iliac crest (TOPIC) or autologous osteochondral transplantation (AOT) procedure for the management of large osteochondral lesions (OCLs) of the talus.

Design: Prospective case series.

Methods: Patients who underwent second-look needle arthroscopy following either TOPIC or AOT procedure were prospectively recruited when they needed a second look.

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The ankle sprain and the domino effect.

Knee Surg Sports Traumatol Arthrosc

December 2024

Department of Orthopedic Surgery and Sports Medicine, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands.

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Unlabelled: With the advent of the first generation of disease-modifying treatments for Alzheimer's disease, it is clearer now more than ever that the field needs to move toward personalized medicine. Pooling data from past trials may help identify subgroups most likely to benefit from specific treatments and thus inform future trial design. In this perspective, we report on our effort to pool data from past Alzheimer's disease trials to identify patients most likely to respond to different treatments.

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The deltoid ligament is constantly formed by four fascicles reaching the navicular, spring ligament complex, calcaneus and talus.

Knee Surg Sports Traumatol Arthrosc

December 2024

Human Anatomy and Embryology Unit, Department of Pathology and Experimental Therapeutics, University of Barcelona, Barcelona, Spain.

Purpose: The medial collateral ligament of the ankle, or deltoid ligament, can be injured in up to 40% of patients who sustain an ankle inversion sprain. Reporting injuries of the deltoid ligament is not easy due to confusion in the current anatomical descriptions, with up to 16 fascicles described, with variable frequencies. The purpose of this study was to clarify the anatomy of the deltoid ligament.

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Over the years, possibilities in ankle arthroscopy have evolved from diagnostic inspection to complex interventional procedures. Further innovation may come from needle arthroscopy, which has improved substantially in image quality in recent years and can now be used for interventional procedures as well. We here present a standardized approach to wide-awake needle arthroscopy of the anterior ankle under local anesthesia.

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Article Synopsis
  • Intravoxel incoherent motion (IVIM)-corrected diffusion tensor imaging (DTI) can help predict return-to-play (RTP) readiness after hamstring injuries, but long scan times limit its usage.
  • The study tested accelerated methods of IVIM-corrected DTI by comparing standard scans and multiband (MB) accelerated scans within a week of injury and at RTP.
  • Results showed that MB acceleration significantly reduced scan duration while maintaining sensitivity to detect hamstring injuries, although the perfusion fraction (f) did not differ between injured and healthy muscles.
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Objectives: Intramedullary nailing is the treatment of choice for most tibial shaft fractures (TSF). However, an iatrogenic pitfall may be rotational malalignment. The aim of this retrospective analysis was to determine predictors of rotational malalignment following intramedullary nailing of TSF.

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Purpose: According to the homeostasis model, patellofemoral pain (PFP) arises as a consequence of disturbed homeostasis of anterior structures of the knee due to vascular insufficiency. Near-infrared spectroscopy (NIRS) allows to measure changes of concentrations (µmol/cm) of (de)-oxygenated hemoglobine (HHb and OHb). The aim was to study differences in patellar hemodynamics between patients and healthy controls.

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Fifteen out of 16 elite athletes showed concomitant low-grade cartilage lesions of the ankle with unstable syndesmotic injuries: concerns from a prospective case series.

BMJ Open Sport Exerc Med

February 2024

Department of Orthopedic Surgery and Sports Medicine, Amsterdam Movement Sciences, Amsterdam UMC Locatie AMC, Amsterdam, Netherlands.

Objectives: This study aimed to determine the incidence rate and characterise the location and severity of cartilage lesions in the ankle in elite athletes undergoing suture-button stabilisation for unstable distal syndesmotic injuries using needle arthroscopic examination. The feasibility and safety of ad hoc needle arthroscopy and its assisted interventions were also assessed.

Methods: This prospective case series included elite athletes undergoing surgical stabilisation between April 2021 and June 2023.

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Embrace responsible ChatGPT usage to overcome language barriers in academic writing.

Knee Surg Sports Traumatol Arthrosc

January 2024

Department for Orthopaedics, Sahlgrenska University Hospital, Institute of Clinical Sciences, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden.

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Injectable implants constitute a newly developed treatment class in the battle against osteoarthritis. They consist of water-formulated supramolecular polymer, coming from a new class of resorbable biomedical materials, and are implanted in encapsulated joints in a liquid form, where they solidify to form a tough, elastic, and cushioning layer between the joint surfaces. To resort any effect, intra-articular delivery should be guaranteed, and the implant should be distributed throughout the entire joint space.

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Enhancing orthopaedic scientific communication: the launch of infographics in the KSSTA journal.

Knee Surg Sports Traumatol Arthrosc

December 2023

Department for Orthopaedics, Institute of Clinical Sciences, Sahlgrenska University Hospital, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden.

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Introduction: Most adult cases of bacterial-septic-arthritis of a native joint are effectively managed with a single surgical debridement, but some cases may require more than one debridement to control the infection. Consequently, this study assessed the failure rate of a single surgical debridement in adults with bacterial arthritis of a native joint. Additionally, risk factors for failure were assessed.

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Objective: To investigate whether preoperative expectations regarding performing work-related knee-straining activities were associated with being dissatisfied 6 months after total knee arthroplasty (TKA) among working patients, and, to identify prognostic factors for being dissatisfied with performing these work-related knee-straining activities.

Design: Multicenter prospective cohort study.

Setting: Orthopedic surgery departments of 7 hospitals in the Netherlands.

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In orthopedic surgery, there is an increasing number of papers about online studies on the reliability of classification systems. Useful classification systems need to be reliable and valid. Measurement of validity can be variable and is prone to observer bias.

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Introduction: In the context of the development of pharmaceutical interventions, expectations and experiences of participants are essential. Their insights may be particularly helpful to address the challenges of recruiting and retaining participants for Alzheimer's disease (AD) clinical trials. We examined clinical trial participants' experiences to optimize trial design in Alzheimer's disease (AD).

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A deeper dive into ChatGPT: history, use and future perspectives for orthopaedic research.

Knee Surg Sports Traumatol Arthrosc

April 2023

Department of Orthopaedics, Institute of Clinical Sciences, Sahlgrenska University Hospital, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden.

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Intelligent innovations for our journal's path forward.

Knee Surg Sports Traumatol Arthrosc

April 2023

Department of Orthopedic Surgery and Traumatology, Head Knee Surgery and DKF Head of Research, Kantonsspital Baselland, Bruderholz, 4101, Bottmingen, Switzerland.

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Does Consulting an Occupational Medicine Specialist Decrease Time to Return to Work Among Total Knee Arthroplasty Patients? A 12-Month Prospective Multicenter Cohort Study.

J Occup Rehabil

June 2023

Department of Public and Occupational Health, Amsterdam Public Health Research Institute, Amsterdam Movement Sciences, Amsterdam UMC, University of Amsterdam, Location AMC, Meibergdreef 9, 1105 AZ, Amsterdam, Netherlands.

Purpose: The aim of this study is to investigate whether total knee arthroplasty (TKA) patients who consulted an occupational medicine specialist (OMS) within 3 months after surgery, return to work (RTW) earlier than patients who did not consult an OMS.

Methods: A multi-center prospective cohort study was performed among working TKA patients, aged 18 to 65 years and intending to RTW. Time to RTW was analyzed using Kaplan Meier and Mann Whitney U (MWU), and multiple linear regression analysis was used to adjust for effect modification and confounding.

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Article Synopsis
  • Cerebral small vessel disease (SVD) is a significant cause of strokes and contributes to vascular cognitive impairment and dementia, highlighting the need for improved clinical trial methodologies aimed at developing new treatments.
  • The Framework for Clinical Trials in Cerebral Small Vessel Disease (FINESSE) was established to create guidelines for optimizing trial designs in SVD, focusing on study populations, clinical endpoints, brain imaging, biomarkers, and innovative trial designs.
  • FINESSE recommendations aim to enhance understanding and treatment of SVD, leveraging recent genetic insights and evaluating the effectiveness of existing cardiovascular interventions in this context.
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Subjective cognitive decline and self-reported sleep problems: The SCIENCe project.

Alzheimers Dement (Amst)

May 2022

Alzheimer's Center Amsterdam, Department of Neurology Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC Amsterdam the Netherlands.

Article Synopsis
  • The study investigates the sleep issues faced by memory clinic patients with subjective cognitive decline (SCD) and how these problems relate to cognition, mental health, and biomarkers.
  • Out of 308 subjects, 64% reported sleep problems, with 35% indicating sleep apnea and 53% suffering from poor sleep quality.
  • The findings suggest that enhancing sleep quality could be a potential treatment avenue for alleviating cognitive complaints in SCD patients, as those with sleep problems showed higher levels of depression and anxiety.
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Purpose: To investigate the short-term clinical outcomes and satisfaction for the first set of patients at our institution receiving in-office needle arthroscopy (IONA) for the treatment of posterior ankle impingement syndrome (PAIS).

Methods: A retrospective cohort study was conducted to evaluate patients who underwent IONA for PAIS between January 2019 and January 2021. Clinical outcomes were evaluated using the Foot and Ankle Outcome Score (FAOS) and Patient-Reported Outcomes Measurement Information System Pain Interference, and Pain Intensity scores.

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Novel values in the radiographic diagnosis of ligamentous Lisfranc injuries.

Injury

June 2022

Department of Orthopaedic Surgery, Foot and Ankle Research and Innovation Laboratory (FARIL), Massachusetts General Hospital, Harvard Medical School, Boston, USA.

Background: Ligamentous Lisfranc instability is commonly missed on unilateral radiographs. However, measurement protocols for bilateral weightbearing radiographs have not been standardized. The primary aim of this study was to investigate the optimal cut-off values for diagnosing Lisfranc instability by evaluating the side-to-side differences of preoperative bilateral weightbearing radiographs among patients with surgically-confirmed ligamentous Lisfranc instability.

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