How Should We Use Hyaluronidase for Dissolving Hyaluronic Acid Fillers?

Background: Hyaluronic acid (HA) fillers are commonly used in esthetic medicine for facial contouring and rejuvenation. However, complications such as overcorrection, vascular occlusion, and irregular filler distribution necessitate the use of hyaluronidase to dissolve the fillers. This study aimed to evaluate the efficacy of hyaluronidase in degrading different types of HA fillers and provide clinical guidelines for its use based on filler type, dosage, and application techniques.

Gold nanorods coated with self-assembled silk fibroin for improving their biocompatibility and facilitating targeted photothermal-photodynamic cancer therapy.

Gold nanorods (AuNRs) have shown great potential as photothermal agents for cancer therapy. However, the biosafety of AuNRs ordinarily synthesized using a cationic ligand assistance procedure has always been a subject of controversy, which limits their application in tumor therapy. In this study, we propose a novel strategy to enhance the biocompatibility of AuNRs by constructing a biological coating derived from silk fibroin (SF) on their surface.

Safety Assessment of Graphene-Based Materials.

Graphene is the first 2D atomic crystal, and its isolation heralded a new era in materials science with the emergence of several other atomically thin materials displaying multifunctional properties. The safety assessment of new materials is often something of an afterthought, but in the case of graphene, the initial isolation and characterization of the material was soon followed by the assessment of its potential impact on living systems. The Graphene Flagship project addressed the health and environmental aspects of graphene and other 2D materials, providing an instructive lesson in interdisciplinarity - from materials science to biology.

Translation, Cross-Cultural Adaptation, and Validation of the Kannada Version of the Exercise Adherence Rating Scale (EARS-Kn) Among Head and Neck Cancer (HNC) Survivors in a Tertiary Care Setup in India.

Background: Adherence in rehabilitation services includes attending appointments, regularly performing prescribed exercises, and correct exercise execution. The Exercise Adherence Rating Scale (EARS) has been adapted into several languages, but there is lack of a standardized tool for various Indian languages and cultural contexts, particularly for use with cancer survivors. With the anticipated 57.

Assessment of clinical characteristics and mortality in patients hospitalized with SARS-CoV-2 from January 2022 to November 2022, when Omicron variants were predominant in the United States.

Objective: To describe the demographic/clinical characteristics, treatment patterns, and mortality among patients hospitalized with COVID-19 during Omicron predominance by immunocompromised and high-risk status.

Methods: Retrospective observational study of patients hospitalized with COVID-19 between January 1, 2022 and November 30, 2022, using data from the Optum de-identified Clinformatics® Data Mart Database. Patient demographic/clinical characteristics, treatments, mortality and costs, were assessed, during the emergence of BA.

Effect of Dendrobium Officinale on Radioactive Oral Mucositis of Nasopharyngeal Carcinoma and Changes of Oral Microecology.

Objective: To observe the clinical efficacy of Dendrobium officinale in the treatment of radiotherapy-induced oral mucositis in nasopharyngeal carcinoma patients, and to explore its regulating effect on immune function and oral microbiota by comparing immune-related factors and oral microbiota before and after the intervention.

Methods: We conducted a randomized double-blinded controlled trial in Zhejiang Cancer Hospital. Sixty patients with nasopharyngeal cancer combined with radiotherapy-induced oral mucositis were randomly divided into a study group and control group, with 30 cases in each group The study group used compound vitamin B12 solution and Dendrobium tea drink, and the control group simply used compound vitamin B12 solution rinse.

Balance Changes in Adult Cancer Survivors Participating in a 16-Week Therapeutic Yoga Program.

Introduction: Balance problems arising from cancer and its treatments can significantly impact daily functionality and quality of life. Improving balance as part of a cancer treatment plan could result in better patient outcomes. Thus, the aim of this study was to determine whether an integrative therapeutic yoga intervention can improve balance in a heterogenous population of cancer survivors (CS).

Exploring the perceptions and cultural differences surrounding mindfulness among early childhood education informal caregivers: A qualitative study.

Background: Early childhood education (ECE) caregivers experience high levels of stress and increased physical and emotional work demands. Promoting mindfulness practices may be an acceptable and feasible strategy to bolster mental health and well-being. The present study's goals were to explore the 1) perceptions and 2) cultural differences surrounding mindfulness practices and mental health among Spanish-speaking Hispanic (SSH), English-speaking Hispanic (ESH), and English-speaking non-Hispanic (ESNH) informal ECE caregivers.

Identifying the factors influencing the quality of education from the perspective of nursing students: A qualitative study.

Background: Nursing education in Iran suffers from challenges such as inadequate training time, non-scientific methods, lack of facilities, and so on. Nursing students can better discuss these issues and identify variables affecting their education. Thus, this study sought to uncover factors affecting education quality from nursing students' perspectives.

Relationship between organizational commitment, working environment, and burnout in clinical nurses.

Background: Burnout is a mental condition caused by chronic emotional or psychological stress. Organizational commitment is always an important issue in the field of organizational development of clinical nurses. The study aimed to assess the association between organizational commitment, work environment, and burnout in clinical nurses.

Assessment of the relationship between thinking styles and learning styles with academic performance in medical and nursing students of Kermanshah University of Medical Sciences.

Background: Learning and studying approaches are among the topics of great importance in medical sciences universities. Different approaches to learning can explain why some students learn better than others. This study aims to assess the relationship between learning or thinking styles and academic performance among nursing and medical students.

Stress level and coping strategies among intensive care nurses: A cross-sectional study.

Background: Intensive care units (ICUs) are high-stress environments, particularly for nurses, who face numerous stressors that can negatively impact their well-being. This study aimed to examine stress levels and stressors among ICU nurses, investigate their stress coping strategies, and explore the primary stressors in this demanding work environment.

Materials And Methods: Employing a cross-sectional design, this study assessed the stress levels of ICU nurses by using the Perceived Stress Scale and their coping strategies through the Brief-COPE scale, from March 15, 2021, to April 14, 2021.

Investigating the effect of yoga-based educational interventions on the volume and composition of breast milk in premature infant's mothers admitted to neonatal intensive care unit: A randomized controlled trial.

Background: This study examined the effects of yoga-based educational interventions on the volume and composition of breast milk in premature infants' mothers admitted to the neonatal intensive care unit (NICU).

Materials And Methods: A randomized controlled trial was conducted on 78 primiparous mothers whose premature infants were less than 34 weeks and were hospitalized in the NICU of Ayatollah Rouhani Hospital from February 2021 to November 2022. Mothers were assigned to a control group and an experimental group, that is, yoga, using the block randomization method.

Analyzing the status of pre-hospital emergency medical services graduates in Iran during the last two decades.

Background: Pre-hospital emergency medical services (PHEMS) training system is an integral part of the health system of any country. Therefore, knowing the status of graduates of this field can provide a new analysis for the policymakers of the National Health System. The purpose of this study was to analyze the status of PHEMS graduates in Iran.

Effectiveness of nurse-led progressive muscle relaxation on stress, anxiety, and depression in parents of adolescents with mental illness: A randomized controlled trial.

Background: Prevention of depression, stress, and anxiety is a serious concern of the World Health Organization and has been a research topic over the last decades. There is a close association found between children's mental health problems and parental stress, valid for biological and foster families. Evidence suggests that parents with children with disabilities are more stressed, depressed, or anxious than parents who do not have such children.

Examining the impact of the exercise package on eye and neck strain (EPENS) among adolescents: A pre-experimental study at a selected preuniversity college in Mangalore.

Background: Electronic devices like laptops, desktops, and cell phones are now essential in modern life, especially for students, due to their convenience and time-saving benefits. However, concerns about social issues related to prolonged use, particularly among kids and teenagers, have arisen. This study aimed to evaluate the efficacy of an exercise package in mitigating symptoms of eye and neck strain among adolescents who are regular users of electronic devices.

Precision medicine and patient outcomes in intensive care unit: Culture sensitivity, antibiotics, and APACHE score IV.

Background: In the intensive care unit (ICU), complex medical conditions require specialized care; the threat of antibiotic resistance is significant due to frequent antibiotic use. This study investigates the pivotal role of culture sensitivity testing in shaping antibiotic prescription practices and patient outcomes in ICUs.

Materials And Methods: By using a prospective observational-analytical design, medical data from 640 patients at a Karachi hospital for one year in 2022 were utilized.

Effect of Cawthorne and Cooksey exercise on balance control and fall risk among middle-aged population: A single group pre-post experimental study.

Background: Balance impairment is one of the causes of the risk of falls among all age groups and is a continuing threat to morbidity and mortality across the world. Previous studies stated that the vestibular system is affected in middle-aged population, which leads to imbalance and a high risk of falls. There is a lack of research in this account so this study has been done to find the effect of Cawthorne and Cooksey exercise in vestibular rehabilitation on balance control and the risk of falls among middle-age population.

Systematic review of ChatGPT accuracy and performance in Iran's medical licensing exams: A brief report.

ChatGPT has demonstrated significant potential in various aspects of medicine, including its performance on licensing examinations. In this study, we systematically investigated ChatGPT's performance in Iranian medical exams and assessed the quality of the included studies using a previously published assessment checklist. The study found that ChatGPT achieved an accuracy range of 32-72% on basic science exams, 34-68.

Behavioral modification strategies for tobacco cessation: A scoping review.

Tobacco use remains a global public health challenge, with numerous associated health risks. Behavioral modification strategies have played a pivotal role in helping individuals achieve and maintain tobacco cessation. This scoping review aims to compare different behavioral modifications for tobacco cessation counseling.

Infection control nurse: A scoping review.

Infection control is a crucial aspect of healthcare delivery aimed at curtailing the spread of infections within healthcare settings. The role of infection control nurses (ICNs) is reported to have a significant contribution in limiting healthcare-associated infections. Scholarly investigations have explored various domains of ICNs.