Examining the Safety of Dorsogluteal and Ventrogluteal Sites for Intramuscular Injection in Older Adults.

Background: Muscle, subcutaneous tissue and total tissue thicknesses are important factors in successful intramuscular injection. Muscle mass decreases and subcutaneous tissue increases with age. This may negatively affect the safety and effectiveness of intramuscular injection in older adults by increasing the risk of bone contact and subcutaneous drug administration.