268,736 results match your criteria: "Republic of Korea; Suncheon Research Center for Natural Medicines[Affiliation]"

Clinical predictors and noninvasive imaging in Fontan-associated liver disease: A systematic review and meta-analysis.

Hepatol Commun

December 2024

Division of Pediatric Cardiology, Department of Pediatrics, Congenital Heart Disease Center, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.

Background: Despite the development of several imaging modalities for diagnosing Fontan-associated liver disease (FALD), there is no optimal protocol for the follow-up of FALD. We conducted a systematic review and meta-analysis to identify factors related to liver fibrosis using biopsy reports and to identify alternative noninvasive modalities that could better reflect liver histological changes in FALD.

Methods: A systematic review and meta-analysis were conducted following the PRISMA guidelines Table S2.

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The Traditional Formula (TF), a combination of herbs prepared in accordance with traditional medicine principles, is increasingly garnering global attention as an alternative to modern medicine. Specifically, there is growing interest in exploring TF's therapeutic effects across various diseases. A significant portion of the state-of-the-art knowledge regarding the relationship between TF and disease is found in scientific publications, where manual knowledge extraction is impractical.

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The cellular characteristics of the opportunistic fungal pathogen Cryptococcus species were investigated in the infected liver of an immunocompetent host using transmission electron microscopy (TEM). With no records of immunodeficiency, the 3-year-old female patient displayed a high-grade fever, lethargy, and increasing jaundice. TEM analysis revealed the presence of round yeast cells in the patient's liver.

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Oral vaccines have several advantages compared with parenteral administration: they can be relatively cheap to produce in high quantities, easier to administer, and induce intestinal mucosal immunity that can protect against infection. These characteristics have led to successful use of oral vaccines against rotavirus, polio, and cholera. Unfortunately, oral vaccines for all three diseases have demonstrated lower performance in the highest-burden settings where they are most needed.

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Energy is integral to the socio-economic development of every country. This development leads to a rapid increase in the demand for energy consumption. However, due to the constraints and costs associated with energy generation resources, it has become crucial for both energy generation companies and consumers to predict energy consumption well in advance.

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How can we recommend items to users utilizing multiple types of user behavior data? Multi-behavior recommender systems leverage various types of user behavior data to enhance recommendation performance for the target behavior. These systems aim to provide personalized recommendations, thereby improving user experience, engagement, and satisfaction across different applications such as e-commerce platforms, streaming services, news websites, and content platforms. While previous approaches in multi-behavior recommendation have focused on incorporating behavioral order and dependencies into embedding learning, they often overlook the nuanced importance of individual behaviors in shaping user preferences during model training.

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Insecticide resistance mutations of Anopheles species in the Republic of Korea.

PLoS Negl Trop Dis

January 2025

Department of Biology, College of Natural Sciences, Kyungpook National University, Daegu, Republic of Korea.

The number of reported malaria cases transmitted by Anopheles mosquitoes in the Republic of Korea (ROK) increased from 420 in 2022 to 746 in 2023, a 77.6% increase. Eight Anopheles species are currently reported in the ROK, including six species belonging to the Anopheles Hyrcanus Group and one species each belonging to the Barbirostris Group and Lindesayi Group.

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Introduction: The ActiGraph (AG) accelerometer is widely used to assess physical activity (PA) in heart failure (HF) patients. However, the validity of the AG in this population remains unexplored.

Objective: Therefore, this study examined the criterion validity of the AG-GT9X for measuring step counts (SC) and energy expenditure (EE) among HF patients.

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The complex dynamics of terahertz (THz) wave scattering by subwavelength-scale structures remain largely unexplored. This article examines the spectral scattering characteristics of subwavelength-sized spherical particles probed by tightly focused THz waves through numerical simulations and experimental techniques. The simulations reveal that the scattering intensity for lower Mie resonance modes (magnetic dipole and electric dipole modes) remains largely unaffected when THz waves are focused down to 0.

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The authors reply.

Crit Care Med

January 2025

Both authors: Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.

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The need to understand subjective health has increased during the COVID-19 pandemic, given its substantial impact on lifestyle habits and perceptions. Thus, this study aimed to investigate the trends and association of subjective health with demographic and behavioral factors, primarily focusing on the change when the COVID-19 pandemic emerged. This study used data from the Korea Youth Risk Behavior Web-based Survey, comprising 1,190,468 adolescents aged 12-18 years (female, 48.

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Objective: To evaluate the effects of postoperative exercise on pain, disability, and quality of life (QoL) after lumbar disc herniation (LDH) surgery.

Design: We systematically searched the PubMed, EMBASE, Cochrane Library, and PEDro databases up to May 2024. Two reviewers independently selected and assessed relevant randomized controlled trials investigating the effectiveness of postoperative exercise after the surgical treatment of patients diagnosed with LDH on low back pain, disability, and QoL assessed using visual analog scale (VAS), Oswestry Disability Index (ODI), and 36-item short-form health survey (SF-36).

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Recent experimental studies showed that electrically coupled neural networks like in mammalian inferior olive nucleus generate synchronized rhythmic activity by the subthreshold sinusoidal-like oscillations of the membrane voltage. Understanding the basic mechanism and its implication of such phenomena in the nervous system bears fundamental importance and requires preemptively the connectome information of a given nervous system. Inspired by these necessities of developing a theoretical and computational model to this end and, however, in the absence of connectome information for the inferior olive nucleus, here we investigated interference phenomena of the subthreshold oscillations in the reference system for which the structural anatomical connectome was completely known recently.

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Somatic copy number deletion of chromosome 22q in papillary thyroid carcinoma.

Eur Thyroid J

January 2025

S Chanock, Division of Cancer Epidemiology and Genetics, Laboratory of Genetic Susceptibility, National Cancer Institute, Bethesda, United States.

Deletion of the long q arm of chromosome 22 (22qDEL) is the most frequently identified recurrent somatic copy number alteration (SCNA) observed in papillary thyroid carcinoma (PTC). Since its role in PTC is not fully understood, we conducted a pooled analysis of genomic characteristics and clinical correlates in 1094 primary tumors from four published PTC genomic studies. The majority of PTC with 22qDEL exhibited arm-level loss of heterozygosity (86%); nearly all PTC with 22qDEL had losses in 22q12 and 13, which together constitute 70% of the q arm.

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Background: Military personnel face an increased risk of developing mental disorders owing to the stressful environments they encounter. Effective stress management strategies are crucial to mitigate this risk. Mindfulness training (MT) is promising as a stress management approach in such demanding settings.

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Background: Despite TSH suppressive therapy improve the prognosis for the patient with differentiated thyroid cancer (DTC), there is an increasing concern regarding the potentially harmful effects of lifelong TSH suppression. Therefore, we aimed to examine the changes in body composition under TSH suppression in postmenopausal women with DTC.

Methods: The body composition was assessed by the volumes as following; fat tissues of the epicardium and abdominal visceral and subcutaneous areas; bilateral psoas muscle or thigh muscle.

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Use of acupuncture among chronic disease patients attending primary healthcare facilities: a cross-sectional study in Korea.

BMC Complement Med Ther

January 2025

Department of Global Health and Development, Graduate School, Hanyang University, 222 Wangsimni-ro, Seongdong-gu, Seoul, 133-791, South Korea.

Background: Given the crucial role of integrating acupuncture treatment into primary care for managing chronic diseases, this study endeavors to identify the utilization of acupuncture among chronic disease patients seeking primary care services in Korea. Additionally, it aims to evaluate their knowledge level and perceptions related to acupuncture use.

Methods: A descriptive cross-sectional study was conducted among chronic disease patients attending a primary care clinic in Korea.

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Background: Various analgesic techniques have been applied, the pain after video assisted thoracic surgery (VATS) is still challenging for anesthesiologists. Paracetamol provide analgesic efficacy in many surgeries. However, clinical evidence in the lung surgery with regional block remain limited.

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Introduction: The clinical feasibility and applicability of surface landmarks for Baxter nerve entrapment to proximal and distal sites is unclear. This study provides anatomical guidelines for optimal transducer placement using two specific landmarks, the most inferior tip of the medial malleolus (A) and the most protruding posterior tip of the calcaneus (B), to enhance the diagnostic and therapeutic injection efficacy for proximal and distal entrapment sites.

Materials And Methods: Eighty-six feet from 45 fresh cadavers (25 male and 20 female) were dissected to determine Baxter's nerve (BN) localization.

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Backgrounds: Digital, online assessments are efficient means to detect early cognitive decline, but few studies have investigated the relationship between remotely collected subjective cognitive change and cognitive decline. We hypothesized that the Everyday Cognition Scale (ECog), a subjective change measure, predicts longitudinal change in cognition in the Brain Health Registry (BHR), an online registry for neuroscience research.

Methods: This study included BHR participants aged 55 + who completed both the baseline ECog and repeated administrations of the CANTAB Paired Associates Learning (PAL) visual learning and memory test.

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Thoracic vertebral body erosion due to a perianeurysmal outpouching lesion after thoracic endovascular aortic repair: a case report and literature review.

BMC Musculoskelet Disord

January 2025

Spine Center and Department of Orthopedic Surgery, Inje University Sanggye Paik Hospital, College of Medicine, Inje University, 1342, Dongil-Ro, Seoul, Nowon-Gu, 01757, Republic of Korea.

Background: The safety of endovascular treatment, such as thoracic endovascular aortic repair (TEVAR), for a descending thoracic aortic aneurysm has been well-established, with a reported low postoperative mortality rate but higher incidences of long-term complications such as endo-leakage, device failure, and aneurysm-related death. Based on this, we report the first case of massive thoracic vertebral body erosion due to a perianeurysmal outpouching lesion after TEVAR.

Case Presentation: A 77-year-old female with a history of TEVAR due to descending thoracic aortic arch aneurysm 4 years ago was referred from the cardiovascular clinic to the spine center.

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Aims: The aim of this study was to evaluate renal artery embolization in patients with spontaneous renal artery bleeding based on detailed angiographic findings and a comprehensive analysis of its efficacy and clinical outcomes.

Materials And Methods: This retrospective study evaluated the outcomes of renal artery embolization in 18 cases among 15 patients (11 men and 4 women; mean age: 57.9 years) treated for spontaneous renal bleeding at our institution between March 2017 and October 2023.

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An organic electrochemical neuron for a neuromorphic perception system.

Proc Natl Acad Sci U S A

January 2025

Department of Chemistry and the Materials Research Center, Northwestern University, Evanston, IL 60208.

Human perception systems are highly refined, relying on an adaptive, plastic, and event-driven network of sensory neurons. Drawing inspiration from Nature, neuromorphic perception systems hold tremendous potential for efficient multisensory signal processing in the physical world; however, the development of an efficient artificial neuron with a widely calibratable spiking range and reduced footprint remains challenging. Here, we report an efficient organic electrochemical neuron (OECN) with reduced footprint (<37 mm) based on high-performance vertical OECT (vOECT) complementary circuitry enabled by an advanced n-type polymer for balanced p-/n-type vOECT performance.

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