10,233 results match your criteria: "Renovascular Hypertension"
The Organum Vasculosum of the Lamina Terminalis Contributes to Neurohumoral Mechanisms of Renal Vascular Hypertension.
Am J Physiol Regul Integr Comp Physiol
December 2024
Department of Surgery, Medical School, University of Minnesota, Minneapolis, MN, USA.
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View Article and Find Full Text PDFUnravelling a mystery of hypokalemic hypertension- a rare case report of a reninoma.
BMC Endocr Disord
December 2024
National Hospital of Sri Lanka, Colombo, Sri Lanka.
Background: Reninoma is a rare cause of secondary hypertension, which can be cured with surgery if identified early before any target organ damage occurs. It leads to hypokalaemia and hypertension and typically responds well to treatment with renin-angiotensin-aldosterone system blockers. However, confirmation of the diagnosis and the localisation of this rare culprit lesion can be challenging.
View Article and Find Full Text PDFModern Open Surgery for Coral Reef Aorta with Visceral Artery Involvement.
Eur J Vasc Endovasc Surg
December 2024
Department of Vascular Surgery, University Hospital of Rangueil, Toulouse, France.
Objective: Coral reef atherosclerosis of the visceral aorta (CRA) is associated with renovascular hypertension (RVH), chronic mesenteric ischaemia (CMI), and malperfusion of the lower limbs (PAD). The outcomes of open surgery for this rare disease are described in this paper.
Methods: This retrospective study included all patients who underwent open surgical repair of CRA at a single high volume referral centre between January 2009 and June 2023.
Renal Infarction in a Newly Diagnosed Atrial Fibrillation Patient.
Cureus
November 2024
Emergency Medicine, St. Mary's Hospital, Isle of Wight NHS Trust, Isle of Wight, GBR.
Renal infarction is a rare but potentially serious condition, often misdiagnosed due to its non-specific presentation, which mimics conditions such as nephrolithiasis and pyelonephritis. Discussed in this case report is a 68-year-old woman who presented to an emergency department with two weeks of worsening left flank pain. She was found to have a new diagnosis of atrial fibrillation (AF) on electrocardiogram (ECG) and CT findings revealing renal infarction.
View Article and Find Full Text PDFEndovascular salvage of renal artery bypass in pediatric a patient with neurofibromatosis type 1.
J Vasc Surg Cases Innov Tech
February 2025
Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Neurofibromatosis type 1 (NF1) is a congenital vasculopathy that can affect the renal arteries, causing renovascular hypertension. We report a complex case of a pediatric NF1 patient who required endovascular salvage of a renal artery bypass. Treatment for pediatric renovascular NF1 requires close surveillance and the ability to pivot to rescue therapies.
View Article and Find Full Text PDFRenal pressure-flow relationship and renin activation in a porcine model comparing unilateral and bilateral renal artery stenosis.
Physiol Rep
December 2024
Heart Center, University Hospital Ghent, Ghent, Belgium.
Article Synopsis
- The study investigates how renal artery stenosis (RAS) affects blood flow and renin release in a pig model, particularly when there is significant stenosis on the opposite kidney side.
- Researchers measured kidney pressure and blood flow while gradually blocking the renal artery to understand how these changes impact renin secretion.
- Findings revealed that a 25% reduction in renal perfusion pressure significantly reduced blood flow and increased renin release, especially when there was already significant stenosis in the contralateral kidney.
Captopril DMSA Contribution in the Identification of the Cause of Severe Hypertension in an Otherwise Healthy 5-Year-Old Girl.
Clin Nucl Med
November 2024
From the Department of Pediatrics, School of Medicine, University of Ioannina, Ioannina, Greece.
Article Synopsis
- A 5-year-old girl with previously normal health was diagnosed with stage 2 hypertension, which is not common in young children and often connected to other disorders.
- Despite normal findings in physical exams and imaging tests like ultrasound and CT scans, blood tests indicated a high renin level and slightly elevated aldosterone, hinting at a potential renovascular issue.
- A specialized renal scan (DMSA) indicated a blockage in a small artery in her kidney, which was successfully fixed through a procedure known as arteriography, emphasizing the usefulness of a captopril DMSA scan in identifying minor kidney artery problems.
Renal Artery Stenosis and Mid-Aortic Syndrome in Children-A Review.
J Clin Med
November 2024
Department of Pediatrics and Nephrology, Medical University of Warsaw, 02-091 Warsaw, Poland.
Article Synopsis
- Renal artery stenosis (RAS) and mid-aortic syndrome (MAS) are important but often overlooked causes of high blood pressure in children, with RAS involving the narrowing of renal arteries and MAS affecting the abdominal aorta and associated vessels.
- These conditions can arise from genetic issues and other factors like fibromuscular dysplasia and Takayasu arteritis, making their symptoms complicated and hard to diagnose despite improved imaging techniques.
- Treatment varies from medications that only partially control blood pressure to more invasive options like angioplasty and surgery, and the article emphasizes the need for a multidisciplinary approach and early detection to improve treatment outcomes for affected children.
Primary congenital abdominal aortic aneurysm associated with renovascular hypertension in pediatric patient.
Future Cardiol
December 2024
Department of Vascular Surgery, Aortic Centre, Hôpital de la Timone, Marseille, France.
Article Synopsis
Characterization of a novel ovine model of hypertensive heart failure with preserved ejection fraction.
Am J Physiol Heart Circ Physiol
December 2024
Manaaki Manawa - The Centre for Heart Research, Department of Physiology, University of Auckland, Auckland, New Zealand.
Article Synopsis
- There is a significant need for better animal models to study heart failure with preserved ejection fraction (HFpEF), as current models do not adequately represent the condition and hinder research on treatments.
- A new model using older female sheep with chronic hypertension was developed, showing key characteristics of HFpEF, such as higher blood pressure and signs of heart dysfunction without obvious systolic impairment.
- This sheep model also exhibited decreased exercise capacity, making it a promising tool for further research to understand HFpEF and potentially improve therapy options.
Multiple Treatment Strategies of Accessory Renal Artery Related Hypertension: Report of Two Cases and Literature Review.
J Clin Hypertens (Greenwich)
December 2024
Department of Vascular Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing, China.
Article Synopsis
- * The report highlights two cases of ARA-related hypertension, one patient managed successfully with medications alone while the other required surgical intervention due to severe conditions affecting both accessory and main renal arteries.
- * While medical therapy is the primary treatment for ARA-related hypertension, interventional procedures may be necessary for patients who do not respond to medication alone.
Renovascular hypertension following by juxtaglomerular cell tumor: a challenging case with 12-year history of resistant hypertension and hypokalemia.
BMC Endocr Disord
November 2024
Department of Endocrinology and metabolism, Guangzhou Red Cross Hospital of Jinan University, No. 396, Tong Fu Zhong Rd, Guangzhou, 510220, China.
Article Synopsis
Renovascular hypertension - a primer for the radiologist.
Abdom Radiol (NY)
November 2024
Yale University, New Haven, USA.
Article Synopsis
Epigenetic DNA Methylation and Protein Homocysteinylation: Key Players in Hypertensive Renovascular Damage.
Int J Mol Sci
October 2024
Department of Physiology, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Article Synopsis
Large Endometrioma That Triggered a Hypertensive Emergency: A Case Report.
Case Rep Obstet Gynecol
October 2024
Department of Obstetrics & Gynecology, University of Arizona College of Medicine, Phoenix, Arizona, USA.
Article Synopsis
- Endometriosis affects many women of reproductive age, causing symptoms like pelvic pain and infertility, with endometriomas being cystic masses usually located on the ovaries.
- The case study highlights a rare instance of a 25-cm endometrioma in a patient who had not been previously diagnosed with endometriosis, leading to an acute hypertensive emergency.
- The treatment involved minimally invasive surgery to remove the cyst and adhesions, which successfully resolved the patient's condition without complications.
Characteristics, treatment, and outcomes of spontaneous renal artery dissection: a 10-year retrospective single-center experience.
Quant Imaging Med Surg
October 2024
Department of Interventional Radiology and Vascular Surgery, Peking University First Hospital, Beijing, China.
Article Synopsis
- Spontaneous renal artery dissection (SRAD) is a rare condition that can lead to kidney failure and high blood pressure, with varied treatment approaches and often delayed diagnosis.* -
- A study analyzing 21 SRAD patients over ten years found that most cases were managed with supportive medical treatment, while interventions like endovascular procedures and nephrectomy were less common.* -
- Results indicated that both medical and interventional treatments successfully maintained stable kidney function and controlled hypertension in patients, suggesting that medical management is generally effective.*
A case report with literature review: long-term follow-up of kidney autotransplantation in fibromuscular dysplasia.
J Nephrol
October 2024
Department of Internal Medicine, Division of Nephrology, Marmara University, School of Medicine, Pendik Research and Education Hospital, Fevzi Cakmak Mah. Mimar Sinan Cd. N:41, Pendik, 34854, Istanbul, Turkey.
Article Synopsis
- * Treatment options include antihypertensive medication, surgical revascularization, and angioplasty, with kidney autotransplantation as an alternative for complex cases.
- * A case study of a 22-year-old woman shows successful kidney autotransplantation led to improved kidney function and controlled blood pressure, highlighting it as a viable solution for severe cases of fibromuscular dysplasia.
Diffusely Increased FDG Uptake of the Kidney Caused by Severe Renal Artery Stenosis.
Clin Nucl Med
December 2024
From the Departments of Nuclear Medicine.
Article Synopsis
- Renal artery stenosis can lead to conditions like renovascular hypertension and ischemic nephropathy, impacting kidney function.
- A case study highlights the use of FDG PET/CT and delayed abdominal FDG PET/MRI imaging to assess a kidney affected by severe renal artery stenosis due to retroperitoneal alveolar echinococcosis.
- The imaging showed increased activity in the renal parenchyma but no activity in the renal collecting system, suggesting that renal artery stenosis should be considered when evaluating diffuse renal parenchymal FDG uptake.
Vascular Abnormalities and Neurofibromatosis Type 1: A Paediatric Case Series.
J Child Neurol
January 2025
Pediatric Clinic, "Microcitemico - A. Cao" Pediatric Hospital, University of Cagliari, Cagliari, Italy.
Article Synopsis
- - Neurofibromatosis type 1 (NF1) is a genetic disorder caused by a mutation that leads to issues like vascular and neurological abnormalities.
- - Serious complications can include moyamoya syndrome, which causes the progressive narrowing of brain arteries, and renal artery stenosis, a common cause of high blood pressure in NF1 patients.
- - The article reviews clinical cases of NF1 vasculopathy, focusing on diagnosis, management, and potential future strategies for screening and treatment options.
Impact of non-immunosuppressive medical therapy on disease progression and complications of Takayasu arteritis: A narrative review.
Autoimmun Rev
December 2024
Department of Rheumatology, Siena University Hospital, Viale Mario Bracci 16, 53100 Siena (SI), Italy.
Article Synopsis
- * Treatment options include glucocorticoids for acute symptoms, with various other non-immunosuppressive therapies (like antihypertensives and statins) being debated for long-term management, although evidence is not definitive.
- * A review of 11 studies involving 204 patients found mixed results for antiplatelets and anticoagulants, while antihypertensives showed some benefits but also risks; further research is needed to establish effective treatment protocols.
Successful emergency renal auto-transplantation in a child with renovascular disease.
J Hypertens
January 2025
Department of Paediatric Nephrology, Evelina London Children's Hospital.
Article Synopsis
Chronic cannabidiol treatment induces cardiovascular improvement in renovascular hypertensive rats.
J Hypertens
January 2025
Biotechnology Center, Federal University of Paraiba, João Pessoa, Brazil.
Article Synopsis
- Cannabidiol (CBD) shows promise in treating cardiovascular issues related to neurodegenerative diseases and has previously shown benefits in reducing blood pressure and oxidative stress in acute studies.
- This study aimed to evaluate the long-term effects of chronic CBD treatment specifically on rats with renovascular hypertension induced by a surgical model.
- Results indicated that chronic CBD significantly lowered blood pressure, improved vascular function, and reduced harmful reactive oxygen species, suggesting its potential as a therapeutic option for cardiovascular problems in hypertension.*
8-Aminoguanine and its actions in the metabolic syndrome.
Sci Rep
September 2024
Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15219, USA.
Article Synopsis
- The metabolic syndrome involves obesity, insulin resistance, dyslipidemia, and hypertension, which can lead to heart and kidney damage.
- In a study on Zucker Diabetic-Sprague Dawley (ZDSD) rats, 8-aminoguanine was tested for its effects on these conditions.
- Results showed that 8-aminoguanine lowered blood pressure, improved diabetes markers, reduced harmful cytokines, and enhanced overall heart and kidney health by rebalancing metabolism.
Mechanism Actions of Coniferyl Alcohol in Improving Cardiac Dysfunction in Renovascular Hypertension Studied by Experimental Verification and Network Pharmacology.
Int J Mol Sci
September 2024
Natural and Biomimetic Medicine Research Center, Tissue-Orientated Property of Chinese Medicine Key Laboratory of Sichuan Province, West China School of Medicine, West China Hospital, Sichuan University, Chengdu 610000, China.
Article Synopsis
- Renovascular hypertension (RH) is a type of secondary hypertension that can harm heart health, increasing the risk of cardiovascular diseases.
- The study explores the effects of Coniferol (CA), known for its ability to relax blood vessels, on RH-related heart conditions using a specific mouse model and heart cell line.
- Results show CA lowers blood pressure and heart inflammation, targeting specific inflammatory pathways, making it a potential therapy for RH-induced heart issues.
OXGR1-Dependent (Pro)Renin Receptor Upregulation in Collecting Ducts of the Clipped Kidney Contributes to Na Balance in Goldblatt Hypertensive Mice.
Int J Mol Sci
September 2024
Institute of Chemistry, Pontificia Universidad Catoólica de Valparaióso, Valparaióso 2340000, Chile.
Article Synopsis
- * The (pro)renin receptor (PRR), important for sodium reabsorption and blood pressure control, is upregulated in intercalated cells of the collecting duct in 2K1C mice, indicating a connection between reduced blood flow and increased blood pressure.
- * Experiments reveal that blocking OXGR1 or using OXGR1 knockout mice hampers PRR upregulation in response