77 results match your criteria: "Renmin Hospital of Wuhan University Wuhan 430060[Affiliation]"
Interferon regulatory factors: at the crossroads of immunity, metabolism, and disease.
Biochim Biophys Acta
February 2015
Department of Cardiology, Renmin Hospital of Wuhan University Wuhan 430060, China; Cardiovascular Research Institute, Wuhan University Wuhan 430060, China. Electronic address:
The interferon-regulatory factor (IRF) family comprises nine members in mammals. Although this transcription factor family was originally thought to function primarily in the immune system, contributing to both the innate immune response and the development of immune cells, recent advances have revealed that IRFs plays critical roles in other biological processes, such as metabolism. Accordingly, abnormalities in the expression and/or function of IRFs have increasingly been linked to disease.
View Article and Find Full Text PDFEffect of Cbfa1 on osteogenic differentiation of mesenchymal stem cells under hypoxia condition.
Int J Clin Exp Med
April 2014
Laboratory of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, Academy of Military Medical Sciences Beijing 100850, China.
Objective: To observe the effect of Cbfa1 on biological characteristics of marrow mesenchymal stem cells under hypoxia.
Methods: The second passage of the MSCs were transfected with Cbfa1 and then cultured in 20% O2 and 3% O2 condition individually. The biological features of the cultured MSCs were assessed by the Real-time PCR.