Accurate determination of motor evoked potential amplitude in TMS: The impact of personal and experimental factors.

Objective: Corticospinal excitability can be quantified using motor-evoked potentials (MEP) following transcranial magnetic stimulation (TMS). However, the inherent variability of MEPs poses significant challenges. We establish a framework using personal and experimental factors to select the optimal number of trials (n) required for reliable MEP estimates.

Effects of Physical Activity and Exercise Interventions on Health Outcomes in Occupational Drivers: A Systematic Review.

Background: Occupational drivers are exposed to a wide range of risk factors, including sedentary behavior and physical inactivity, which can contribute to various chronic diseases. However, exercise interventions are likely to alleviate the negative associations and reduce chronic disease risks. This systematic review aimed to inventorize research studies investigating the effects of physical activity and exercise interventions on health outcomes in occupational drivers, and to assess interventions that have demonstrated effectiveness on health outcomes in occupational drivers.

The impact of social frailty on mortality in older patients with chronic heart failure: A prospective cohort study.

Background: There is still insufficient longitudinal evidence regarding the risk of mortality in older patients with chronic heart failure (CHF) and social frailty (SF).

Objectives: The purpose of study was to describe the incidence rate of non-SF, pre-SF, and SF in older patients with CHF and explore its impact on mortality.

Methods: The observational study was conducted at a tertiary hospital in China.

Gout: global epidemiology, risk factors, comorbidities and complications: a narrative review.

Background: Gout is one of the oldest known diseases and the most common form of inflammatory arthritis. The established risk factors for gout include hyperuricemia, chronic renal disease, genetic, alcohol consumption, dietary factors, diuretic use, hypertension, obesity, and metabolic syndrome. Patients with gout have an increased risk of all-cause mortality, particularly from cardiovascular disease, cancer, and infectious diseases.

Impact of shock index (SI), modified SI, and age-derivative indices on acute heart failure prognosis; A systematic review and meta-analysis.

Background: Heart failure (HF) is still associated with quite considerable mortality rates and usage of simple tools for prognosis is pivotal. We aimed to evaluate the effect of shock index (SI) and its derivatives (age SI (ASI), modified SI (MSI), and age MSI (AMSI)) on acute HF (AHF) clinical outcomes.

Methods: PubMed/Medline, Scopus and Web of science databases were screened with no time and language limitations till February 2024.

Temporal trend of short-term mortality in acute myocardial between 2000-2017: A multi-centric Iranian registry.

Background: The study explores the enduring challenges of cardiovascular disease mortality, emphasizing myocardial infarction rates as a proxy for cardiovascular disease in Iran. It analyzes the 28-day mortality trends after Acute Myocardial Infarction (AMI) from 2000 to 2017.

Methods: This retrospective cohort study is based on data from a multi-centric hospital-based registry in Isfahan.

Postural adjustment and muscle activity during each phase of gait initiation in chronic ankle instability: an observational study.

Background: Gait initiation (GI) can be divided into three sections according to the center of pressure (COP) trace (S1, S2, and S3). Almost all studies do not separate each phase of the GI profile in postural control assessment and muscular investigation, whereas differences in the COP and muscles are found in each phase of the GI profile in people with gait problems.

Methods: Twenty individuals with CAI and twenty healthy controls were included in the present study.

Risk Factors for Complications in Reconstructing Congenital Femoral Deficiency.

Background: Congenital femoral deficiency (CFD) is a rare condition, often associated with other skeletal anomalies that make the management more difficult. This study aimed to present the risk factors associated with complications in reconstruction of CFD.

Methods: This was a retrospective cohort study on patients with CFD who underwent femoral reconstruction between 2002 and 2022, from a single center.

Challenges in Toileting Evaluation and Interventions for Children With Cerebral Palsy: A Delphi Study.

Importance: Toileting difficulties have a significant impact on the daily lives of children with cerebral palsy (CP), yet research on this issue remains inadequate. There is a critical need to better understand the challenges health care professionals face in addressing toileting difficulties.

Objective: To explore challenges faced by health care professionals in toileting evaluation and interventions for children with CP ages 6-18 yr.

Corneal thickness, contrast sensitivity and binocular vision in menopausal and non-menopausal women.

Objective: This study aimed to investigate the effects of menopause on ocular health and visual function.

Method: Sixty-two women (31 premenopausal and 31 postmenopausal) who visited Rasht Health Center were selected and matched based on their ages and compared in terms of their hormonal status, central corneal thickness (CCT), contrast sensitivity (CS), binocular vision variables and refractive error.

Results: CCT and corneal curvature were significantly thinner in postmenopausal women.

Impact of postural variations on trunk rotation angle during the forward bending test in adolescents idiopathic scoliosis.

Purpose: To evaluate the impact of different positions of adolescent idiopathic scoliosis (AIS) patients and examiners on the angle of trunk rotation (ATR) measured during the forward bending test (FBT) with Scoliometer.

Methods: Adolescents who had come to the hospital for outpatient were recruited. Considering the location of the subject and the examiner, four postural combinations of ATR were measured.

Minimally invasive neurosurgery: application of burr-hole technique across a spectrum of brain lesions.

Objective: The burr-hole technique is a minimally invasive transcranial approach designed to minimize the surgical incision size and reduce disruption to brain tissue. We aimed to share our experience with the burr-hole technique for removing brain lesions and to evaluate its effectiveness in treating appropriately sized intra-axial brain lesions.

Methods: In this retrospective cohort study, we analyzed the clinical features, radiological characteristics, surgical techniques, and outcomes of patients who underwent burr-hole surgery for intra-axial brain lesions between January 2019 and December 2023.

Short-term effects of home-based pulmonary rehabilitation during outpatient-managed exacerbations of COPD: a randomised controlled trial.

Background: Uncertainty exists about the beneficial effects of delivering pulmonary rehabilitation (PR) during exacerbations of chronic obstructive pulmonary disease (ECOPD). This study explored the short-term effects and self-reported impact of a home-based PR programme for people with outpatient-managed ECOPD.

Methods: We conducted a mixed-methods randomised controlled trial in people with outpatient-managed ECOPD.

Exploring App-Based Physiotherapy for Somatic Tinnitus: Results from a Pilot Study.

Somatic tinnitus (ST) is a type of tinnitus that is influenced by changes in somatosensory input from the cervical spine or temporomandibular area. Although traditional physiotherapy has been shown to reduce ST symptoms, in-clinic treatment is not always available, and adherence to home exercise programs is often low. This study aims to investigate the effectiveness of an app-based physiotherapy program to enhance the compliance and availability of treatment for ST patients.

Feature derivation and classification of auditory-motor coupling dynamics in healthy and neurologically impaired adults.

The use of auditory stimuli in rehabilitation to target walking has been evidenced in persons with neurological conditions. The methodologies focus on the synchronisation of persons' steps to auditory stimuli showing that the type of stimuli and tempi significantly affect the synchronisation. However, the dynamic of the interaction over time between the motor system and the auditory stimuli, i.

Abnormal characteristics in disorders of consciousness: A resting-state functional magnetic resonance imaging study.

Aims: To explore the functional brain imaging characteristics of patients with disorders of consciousness (DoC).

Methods: This prospective cohort study consecutively enrolled 27 patients in minimally conscious state (MCS), 23 in vegetative state (VS), and 25 age-matched healthy controls (HC). Resting-state functional magnetic resonance imaging (rs-fMRI) was employed to evaluate the amplitude of low-frequency fluctuation (ALFF), regional homogeneity (ReHo), degree centrality (DC), and functional connectivity (FC).

Occupational Performance Coaching on Health Self-Care Behavior and Activity Participation for Adults With Heart Failure: A Randomized Controlled Trial.

Importance: Patients with heart failure (HF) experience restrictions in their activity participation. Health self-care behavior (HSCB) among patients with HF is an essential component of managing HF symptoms.

Objective: To assess the effect of occupational performance coaching (OPC) on improving activity participation and HSCB among patients with HF.

Evaluation of Abdominal Muscle Thickness Changes During Abdominal Hollowing Maneuver in Different Positions Using a Sphygmomanometer for People With Chronic Low Back Pain.

Objective: The aim of this present investigation was to compare changes in transverse abdominis (TrA) thickness in a functional position with those in a less functional but more supportive posture and to determine which posture showed greater changes in TrA thickness between rest and during abdominal drawing-in maneuver (ADIM) relative to external oblique (EO) and internal oblique (IO) muscles.

Methods: Thirty adult participants with chronic low back pain were included in this observational study. The abdominal muscle thickness was measured in the supine, crook lying, prone, quadruped, sitting, side bridge, and standing poitions on a tilt board using ultrasonography.

Reporting and Methodological Quality of Systematic Reviews and Meta-Analyses Evaluating Effects of Extracorporeal Shock Wave Therapy on Tendinopathies: A Scoping Review.

Objective: The purpose of this study was to evaluate the methodological and reporting quality of the published systematic reviews with or without meta-analyses (SRs/MAs) that looked at the effects of extracorporeal shock wave therapy (ESWT) on tendinopathies and to summarize its effectiveness.

Methods: A search of PubMed, Scopus, PEDro, Web of Science, Cochrane, Embase, and REHABDATA was conducted. SRs/MAs that assessed the effectiveness of ESWT for treating tendinopathy were included.

GsMTx4 Combined with Exercise Exerts Neuroprotective Effects by Regulating Neuronal Autophagy in Rats with Spinal Cord Injury.

A sharp increase in intramedullary pressure after spinal cord injury (SCI) can aggravate secondary injury and lead to severe neurological deficits. Unfortunately, effective treatment options are currently lacking. The mechanosensitive ion channel Piezo1 plays an important role in the pathological process of SCI by transducing mechanical stress.

Children's amputee mobility predictor-Assessing the functional capability of children with leg length discrepancy.

Objective: The study purpose was twofold: (1) to develop the Children's Amputee Mobility Predictor and establish its content and social validity and (2) to determine its intra and inter-rater reliability.

Design: A reliability and validity study.

Setting: Pediatric rehabilitation hospital.

Impact of Tissue Factor Gene Knockout on Coagulation Properties of Umbilical Cord-Derived Multipotent Mesenchymal Stromal/Stem Cells.

Multipotent mesenchymal stromal/stem cells (MSCs) refer to a population of stem cells that exhibit distinct progenitor cell characteristics including the potential for differentiation into a wide range of cell types. MSCs have become a promising candidate for cell therapy and tissue regeneration due to their unique properties, such as their ability to differentiate into multiple cell types, their capacity for expansion, self-renewal, and immune-regulatory effects. However, reports have brought attention to thrombosis-related complications associated with MSCs therapy in the last decade.

Serum Level of RIPK1/3 Correlated With the Prognosis in ICU Patients With Acute Ischemic Stroke.

Background: Acute ischemic stroke (AIS) is a common cerebrovascular disease with high mortality. AIS patients in the intensive care unit (ICU) often have severe conditions that require close monitoring and timely treatment. Receptor-interacting protein kinase 1 (RIPK1) and RIPK3 play important roles in cell apoptosis and inflammation.