13,693 results match your criteria: "Regional Specialist Hospital Center for Research & Development[Affiliation]"

Background: Patients residing in rural and frontier areas experience worse thyroid cancer outcomes than those in urban areas. This novel qualitative study sought the perspectives of rural surgeons to identify practical measures that could mitigate the disparities in thyroid cancer care between rural and urban contexts.

Methods: We contacted general and head and neck surgeons at all of California's Critical Access Hospitals (n = 35), which are remote, rural hospitals, and requested self-referral to our study through the American College of Surgeons.

View Article and Find Full Text PDF

Objective: To compare the management-related practices and knowledge levels of family physicians about newborns, and to identify the factors that affected their practices and knowledge levels.

Methods: The descriptive study was conducted at Ankara Yıldırım Beyazıt University Yenimahalle Training and Research Hospital, Ankara, Turkiye from August to November 2021, and comprised general practitioner family physicians, family medicine specialists and family medicine residents. Data was collected using a 26-item e-survey prepared on Google Forms that covered demographic and occupational information, including neonatal practices and knowledge regarding newborn follow-up.

View Article and Find Full Text PDF

Despite the growing interest in social prescribing the diversification of health and social care strategies to support the well-being of patients has remained entrenched with a focus on the hospital setting within the Middle East. The United Arab Emirates has commenced progressing community mental health care to lead changes in how care and treatment are delivered within the United Arab Emirates. The authors adopted the use of the framework of Arksey and O'Malley (2005) to provide a systematic approach to searching the literature and creating a comprehensive foundation to guide the review.

View Article and Find Full Text PDF

Introduction: Patients with irritable bowel syndrome (IBS) often experience psychiatric disorders such as anxiety and depression. This study examined the association between IBS and anxiety and depression and explored how these variables interact with various IBS indices in the general population of Hail, Saudi Arabia.

Methods: This cross-sectional descriptive study utilized standardized assessments for diagnosing IBS, anxiety, and depression.

View Article and Find Full Text PDF
Article Synopsis
  • People with resistant hypertension (RH) face a greater risk of serious heart-related issues, prompting the British and Irish Hypertension Society to recommend specialist guidance for better blood pressure control.
  • The position statement offers a practical framework for diagnosing and managing adults with RH, while also addressing the current evidence gaps in the field.
  • The overall goal is to enhance the quality and consistency of care for individuals with RH throughout the UK and Ireland.
View Article and Find Full Text PDF

Background: There is still limited data on Discharge Against Medical Advice (DAMA) in the pediatric population. Most research comes from low-and middle-income countries, where the financial burden associated with medical care is often an important reason to leave a healthcare facility prematurely. Discharge against medical advice in the children's population is considered a significant issue that may lead to an increased risk of morbidity and mortality.

View Article and Find Full Text PDF

Background: Semaglutide, a glucagon-like peptide-1, is an effective antidiabetic drug promoting weight loss and providing cardiovascular protection. The original trials did not include participants from Saudi Arabia; hence, the study's findings are expected to be useful.

Objectives: Explore the efficacy, safety, and favorable effects of once-weekly subcutaneous semaglutide (1 mg) in patients with type 2 diabetes and those who received it as an off-license prescription without having diabetes.

View Article and Find Full Text PDF

Objective: To assess the safety and degree of preparation of public hospitals in the district of Lima to provide healthcare in the event of disaster by studying their structural and nonstructural safety and their compliance with the established standards for the organization of the hospital's Emergency Operations Centers (EOCs).

Design: A cross-sectional observational study of 20 out of the 38 public hospitals in the district of Lima was conducted. The hospitals were selected based on the criteria of being state-run, having complete information on open access safety indicators, and belonging to Categories II and III according to the Peruvian Ministry of Health classification, equivalent to the usual secondary and tertiary levels of specialization hospitals.

View Article and Find Full Text PDF

De-escalation of dual antiplatelet (DAPT) intensity may be considered in patients with high risk of bleeding after acute coronary syndrome. Some high risk patients after de-escalation may require antithrombotic therapy prolonged over 12 months. With the current guideline recommended strategies, there are some doubts and uncertainties with respect to the transition period.

View Article and Find Full Text PDF

Clinicians and people with narcolepsy report varied access to higher-cost narcolepsy treatments in England associated with variations in national and local commissioning. There are no publicly available data quantifying use of these drugs to support policy decisions. We therefore aimed to describe national, regional and local prescribing trends for higher-cost narcolepsy drugs using new national databases.

View Article and Find Full Text PDF
Article Synopsis
  • The text discusses the importance of forecasting future health issues in the USA for effective planning and public awareness regarding disease and injury burdens.
  • It describes the methodology for predicting life expectancy, cause-specific mortality, and disability-adjusted life-years (DALYs) from 2022 to 2050 using the Global Burden of Diseases framework.
  • The forecasting includes various scenarios to assess the potential impacts of health risks and improvements across the country, focusing on demographic trends and health-related risk factors.
View Article and Find Full Text PDF

Background: The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides a comprehensive assessment of health and risk factor trends at global, regional, national, and subnational levels. This study aims to examine the burden of diseases, injuries, and risk factors in the USA and highlight the disparities in health outcomes across different states.

Methods: GBD 2021 analysed trends in mortality, morbidity, and disability for 371 diseases and injuries and 88 risk factors in the USA between 1990 and 2021.

View Article and Find Full Text PDF

Unraveling the Prognostic Role of t(1:19) in Pediatric Pre-B Acute Lymphoblastic Leukemia: Insights from a Saudi Nationwide Cohort.

Cancer Genet

January 2025

Department of Oncology, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia; Hematology Department, Faculty of Medicine, King Abdulaziz University Hospital, King Abdulaziz University, Jeddah, Saudi Arabia; Hematology Research Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.

Recurrent translocation t(1;19) (q23;p13) describes a unique cytogenetic group of childhood B-cell acute lymphoblastic leukemia (ALL). Historically, t(1;19)(q23;p13.3) has been associated with poor outcomes.

View Article and Find Full Text PDF

Hepatitis D virus (HDV) prevalence data and country-specific HDV guidelines are not widely available in the Gulf Cooperation Council (GCC) states. We developed consensus recommendations to guide healthcare professionals, policymakers, and researchers in improving HDV management and patient health outcomes in three GCC states: Kuwait, Saudi Arabia, and the United Arab Emirates. A consensus panel comprising hepatology experts (n = 6) from the three GCC societies was formed.

View Article and Find Full Text PDF

Use of individualized starting dose and niraparib hematologic adverse event management costs in ovarian cancer.

J Comp Eff Res

January 2025

Medical Oncology Department, Program in Solid Tumours, CIMA, Cancer Center Clínica Universidad de Navarra, Madrid, and Grupo Español de Investigación en Cancer ginecológicO (GEICO), Madrid, 28027, Spain.

Article Synopsis
  • The study analyzes the cost differences in managing hematologic adverse events (AEs) for the individualized starting dose (ISD) versus the fixed starting dose (FSD) of niraparib from a US payer perspective.
  • Data from a phase III trial provided AE occurrence rates, and costs were calculated based on 2020 adjustments from a healthcare database.
  • Results showed that managing AEs was significantly cheaper with ISD ($6744.93) compared to FSD ($12,987.71), suggesting ISD not only cuts costs but also improves patient safety.
View Article and Find Full Text PDF
Article Synopsis
  • A new study in the French West Indies examines the connection between chlordecone pesticide soil contamination and cancer rates in Martinique from 2006 to 2019, using a more sensitive contamination indicator.
  • This study analyzed data from 23,218 cancer cases, finding that women exposed to higher soil contamination levels showed an increased risk for several cancers, including lung and thyroid cancer, while no significant correlation was observed for breast or prostate cancer.
  • The findings suggest that women in Martinique are disproportionately affected by chlordecone exposure, highlighting the need for ongoing research into the environmental impacts of pesticides on public health.
View Article and Find Full Text PDF

In previous studies, surgical specialties accounted for most malpractice claims. The objective of the present study was to determine the risk for malpractice claims for physicians working in hospitals. A retrospective observational study using anonymized closed malpractice claims between 2007 up to 2021 from two Dutch insurers was carried out.

View Article and Find Full Text PDF

Aim: Digital health interventions and economic incentives have shown promise in facilitating diabetes self-management, though evidence is limited. Therefore, this study aimed to evaluate the effectiveness and cost-effectiveness of a comprehensive app-based diabetes self-management programme with rewards for healthy behaviours and health outcomes.

Materials And Methods: The TRIal to slow the Progression Of Diabetes (TRIPOD) study was an open-label, parallel-group, randomised controlled trial conducted at Duke-NUS Medical School, Singapore.

View Article and Find Full Text PDF

Epilepsy surgery education and practice around the globe: An ILAE taskforce report.

Epilepsia

December 2024

Department of Neurosurgery, Epilepsy Surgery Program, Cliìnica Cukiert, São Paulo, Brazil.

Up to 80% of the world's population with epilepsy lives in low and middle-income countries. Around one-third of these patients will have drug-resistant epilepsy, for which epilepsy surgery is an option. Unfortunately, many of these regions, as well as some more developed nations, lack sufficient epilepsy surgery units and trained neurosurgeons.

View Article and Find Full Text PDF

Background: Children with an intellectual disability (ID) are 3-4 times more likely to present with behaviors that challenge and mental health problems than typically developing children. Parenting and the quality of parent-child relationships are risk factors for these families. The COVID-19 pandemic further exacerbated difficulties, leading to an increase in child mental health problems and behaviors that challenge, a deterioration in parental mental health, and further strain on family relationships.

View Article and Find Full Text PDF

Timing of Dexamethasone Initiation and Its Impact on the Outcome of COVID-19 Patients.

Cureus

November 2024

Division of Internal Medicine, Department of Medicine, King Abdulaziz Medical City, Ministry of National Guard Health Affairs (MNGHA), Riyadh, SAU.

Introduction COVID-19 emerged in Wuhan in December 2019 and was declared a pandemic in March 2020. Severe cases manifest with respiratory distress. Corticosteroids, initially debated, are now recommended for severe cases following the RECOVERY (Randomised Evaluation of COVID-19 Therapy) trial findings.

View Article and Find Full Text PDF

Services Addressing Mental Health Needs of Youth in Physical Rehabilitation: Perspectives of Clinicians, Youth and Family Members.

Child Care Health Dev

January 2025

School of Physical and Occupational Therapy, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada.

Article Synopsis
  • Limited understanding of mental health services for youth with physical disabilities in rehabilitation settings prompted a study to identify needs and challenges.
  • A qualitative approach involved 22 interviews with youth, families, and clinicians from five rehabilitation centers, leading to three key themes: resources, clinician capacity, and partnerships.
  • Findings highlight barriers like lack of mental health knowledge and access during transitions, suggesting that improved training, staffing, and external collaboration can enhance service delivery.
View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to understand the experiences of people with obesity who struggled with weight at an early age (EAO) versus those who faced challenges later in life (LAO), focusing on their interactions with healthcare practitioners (HCPs) and mental health issues like depression and anxiety.
  • Analysis of responses from 1,000 adults showed that EAO individuals had fewer weight loss attempts, less support from HCPs, and higher levels of anxiety and depression, compared to LAO individuals.
  • The conclusion emphasizes the need for HCPs to identify and address weight management issues earlier in life, specifically in adolescents, while involving parents in decision-making to improve motivation and self-confidence in overcoming obesity.*
View Article and Find Full Text PDF

Objective: The serratus anterior plane block (SAPB) is a regional anaesthesia technique with increasing use as an analgesic adjunct in patients with rib fractures. The present study aimed to generate consensus of the requirements of education, training and credentialing for the use of a 'single shot' SAPB in the management of rib fractures.

Methods: A modified Delphi process was designed using online questionnaires.

View Article and Find Full Text PDF