32 results match your criteria: "Regional Dermatology Training Centre[Affiliation]"

High content of hexavalent chromium in cement samples from three African countries.

Contact Dermatitis

November 2024

LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

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Introduction: Dermoscopy has evolved over the years beyond distinguishing benign pigmented lesions from melanoma to diagnosing virtually all diseases in dermatology. Overwhelming evidence demonstrates its utility in improving diagnostic accuracy, reducing unnecessary biopsies and lesion monitoring. Dermoscopy is widely used in Western nations, hence most descriptions of lesions in literature are predominantly on Fitzpatrick skin types I-III.

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Contact allergens in African countries: A review of published patch test studies.

Contact Dermatitis

February 2024

LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Only few studies on contact allergy in African countries have been published. The aim of the present study was to provide an overview of the most common contact allergens identified by the use of patch tests in African countries based on a review of the existing literature. A total of twenty-four publications from eight African countries were initially identified by search in PubMed.

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Article Synopsis
  • Oculocutaneous albinism (OCA) leads to reduced melanin in skin, increasing the risk of skin damage and cancer, with cryotherapy being the common treatment in resource-limited areas like Tanzania.
  • A study involved 12 participants from a skin surveillance clinic, who received daylight photodynamic therapy (dPDT) for actinic damage and provided feedback on its tolerability and acceptability.
  • Results showed that dPDT was mostly well-tolerated, significantly reducing actinic damage by 25-90% without causing any new skin cancers, suggesting it may be a safe treatment option for OCA patients in Tanzania.
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Be aware: 'Leprosy'! Not for nothing an NTD.

J Eur Acad Dermatol Venereol

July 2023

Foundation of Global Dermatology, Munnekeburen, the Netherlands.

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Mycetoma in Moshi, Tanzania.

Trans R Soc Trop Med Hyg

April 2021

St Johns Institute of Dermatology, King's College London, London, UK.

The geographic spread of the neglected tropical disease mycetoma is still poorly understood, largely because there is no mechanism for official reporting and the general lack of identification facilities in many regions. Nonetheless many countries in the tropics have such cases. This brief report is submitted to provide an example of recent experience of mycetoma in six patients presenting to a single centre in Tanzania.

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Pioneers in Dermatology and Venereology: an interview with Prof. Dr. med. Hans-Henning Grossmann.

J Eur Acad Dermatol Venereol

July 2020

Regional Dermatology Training Centre (RDTC) at Kilimanjaro Christian Medical Centre (KCMC), K.C.M. University College (KCMU - Co), Moshi, Tanzania.

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Position statement: LEPROSY: Diagnosis, treatment and follow-up.

J Eur Acad Dermatol Venereol

July 2019

Department of Dermatovenereology, Ayder Referral Hospital Mekelle University, Mekelle, Tigray, Ethiopia.

Background: Leprosy or Hansen's disease is a chronic infection caused by Mycobacterium leprae (M. leprae) or Mycobacterium lepromatosis (M. lepromatosis).

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Background: Papulosquamous skin diseases can be challenging to diagnose, especially in dark skin. Dermoscopy is reported to be helpful, but few data are available on its use in skin type IV or darker.

Objective: To describe dermoscopic features in plaque-type psoriasis (PP), lichen planus (LP), and pityriasis rosea (PR) patients attending the Regional Dermatology Training Centre in Moshi, Northern Tanzania, and to compare findings with published data.

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Background: Kaposi's sarcoma (KS) is a multifocal angioproliferative tumor involving blood and lymphatic vessels, caused by Human Herpes Virus-8 (HHV-8). KS is an important AIDS-defining tumor with high prevalence in Sub-Saharan Africa, including Tanzania which has high HIV and HHV-8 sero-prevalence. It is critically important to monitor the prevalence of AIDS-defining tumors, such as KS, in the age of HIV/AIDS.

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World leprosy day 2018: How forward respecting the past?

Indian J Med Res

January 2018

Foundation Global Dermatology, Munnekeburen, The Netherlands; Regional Dermatology Training Centre, Moshi, Tanzania; Instituto Lauro de Souza Lima, Bauru, SP, Brazil; Department of Dermatology, Ayder Referral Hospital, University of Mekelle, Mekelle, Tigrae, Ethiopia.

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Exploring the Role of IL-32 in HIV-Related Kaposi Sarcoma.

Am J Pathol

January 2018

Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, the Netherlands; Radboud Center of Infectious Diseases, Radboud University Medical Centre, Nijmegen, the Netherlands.

The intracellular proinflammatory mediator IL-32 is associated with tumor progression; however, the mechanisms remain unknown. We studied IL-32 mRNA expression as well as expression of other proinflammatory cytokines and mediators, including IL-1α, IL-1β, IL-6, IL-8, tumor necrosis factor (TNF)-α, the proangiogenic and antiapoptotic enzyme cyclooxygenase-2, the IL-8 receptor C-X-C chemokine receptor (CXCR) 1, and the intracellular kinase focal adhesion kinase-1. The interaction of IL-32 expression with expression of IL-6, TNF-α, IL-8, and cyclooxygenase-2 was also investigated.

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To our knowledge, this is the first case report of juvenile dermatomyositis (JDM) in Tanzania. It demonstrates that the characteristic cutaneous findings of JDM may easily be overlooked, especially on dark skin, and the difficulty of clinical management in resource-constrained settings.

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Background: As global population of the elderly continues to rise, a critical need to provide it with health services, including dermatology, will be significant, especially in developing countries like Tanzania. To adequately meet their dermatologic needs, knowledge of local patterns of skin conditions is vital. This study was aimed to describe the spectrum of skin diseases among elderly patients attending skin clinic at the Regional Dermatology Training Centre (RDTC) in Northern Tanzania.

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Background: Proper diagnosis of skin diseases relies on dermatopathology, the most important diagnostic technique in dermatology. Unfortunately, there are few dermatopathology institutions in sub-Saharan Africa, where little is known about the spectrum of histopathological features observed.

Objectives: To investigate the spectrum of dermatopathological diagnoses made in a sub-Saharan African reference centre of a large, mainly rural area.

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Introduction: The high rate of relapse of acne lesions following oral isotretinoin treatment is a common problem which remains unsolved. To avoid or minimize relapses, topical retinoids have been used for many years as maintenance treatment. However, adverse effects frequently occur.

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