12 results match your criteria: "Recanati Center for Medicine and Research[Affiliation]"

Factors Affecting the Upper Limit of the Methotrexate (MTX) CSF Levels Achievable in Children With Brain Tumors Treated With High-dose Intravenous MTX.

J Pediatr Hematol Oncol

October 2016

*Department of Pediatric Hematology-Oncology, Schneider Children's Medical Center of Israel ‡Recanati Center for Medicine and Research and Clinical Pharmacology Unit, Rabin Medical Center-Beilinson Hospital, Petach Tikva †Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Background: Little has been published in the medical literature on serum and cerebrospinal fluid (CSF) methotrexate (MTX) levels in children with brain tumors.

Methods: Matched 24-hour serum and CSF MTX levels were studied after 113 treatments in 35 brain tumors patients.

Results: A correlation between the 24-hour serum levels of MTX and MTX dosage was observed after 113 treatments in all 35 patients (r=0.

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Background: There is a striking increase in the number of people with metabolic syndrome (MetS) as a result of the global epidemic of obesity and diabetes. Increasing evidence suggests that uric acid may play a role in MetS.

Objectives: To assess the prevalence of MetS in a large cohort from Israel and its association with hyperuricemia using the latest three definitions of MetS.

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Blood transfusion for acute decompensated heart failure--friend or foe?

Am Heart J

October 2009

Recanati Center for Medicine and Research, Rabin Medical Center, Beilinson Campus, Petah Tiqwa, Israel.

Background: In acute coronary syndromes (ACSs), blood transfusion (BT) has been associated with worse outcomes. The impact of BT among patients with acute decompensated heart failure (ADHF) remains unknown.

Methods: Propensity score analysis of patients with ADHF with and without BT in a national heart failure (HF) survey was used in this study.

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Pulmonary Mycobacterium simiae infection: comparison with pulmonary tuberculosis.

Eur J Clin Microbiol Infect Dis

October 2008

Recanati Center for Medicine and Research, Rabin Medical Center, Beilinson Hospital, Petah Tiqwa, Israel.

To identify the clinical and radiological features distinguishing Mycobacterium simiae respiratory infection from pulmonary tuberculosis, the demographics, underlying conditions, and clinical and radiological findings of 121 consecutive patients with pulmonary tuberculosis and 102 with M. simiae respiratory infection were compared retrospectively. In the M.

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Assessment of orthostatic hypotension in the emergency room.

Blood Press

May 2007

Recanati Center for Medicine and Research and Clinical Pharmacology Unit, Rabin Medical Center, Beilinson Campus, Petah Tiqwa, Israel.

The study sought to determine the duration of standing needed to detect most cases of orthostatic hypotension (OH) in the emergency room (ER) and to correlate OH with symptoms, hospitalization and survival. Patients attending a tertiary-center ER within a 2-month period underwent orthostatic tests after 1, 3 and 5 min of standing. OH was defined as a drop of > or = 20 mmHg in systolic pressure or > or = 10 mmHg in diastolic pressure on assuming an upright posture.

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Like other complex, multifaceted interventions in medicine, meditation represents a mixture of specific and not-so-specific elements of therapy. However, meditation is somewhat unique in that it is difficult to standardize, quantify, and authenticate for a given sample of research subjects. Thus, it is often challenging to discern its specific effects in order to satisfy the scientific method of causal inferences that underlies evidence-based medicine.

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Lack of standards in informed consent in complementary and alternative medicine.

Complement Ther Med

June 2005

The Recanati Center for Medicine and Research, Rabin Medical Center, The Tel-Aviv University, Petah Tikva 49100, Israel.

Objectives: To examine whether U.S.-based professional complementary and alternative medicine (CAM) organizations have explicit informed consent policies.

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Methodological challenges in meditation research.

Adv Mind Body Med

July 2005

Recanati Center for Medicine and Research, Rabin Medical Center, Israel.

Like other complex, multifaceted interventions in medicine, meditation represents a mixture of specific and not-so-specific elements of therapy. However, meditation is somewhat unique in that it is difficult to standardize, quantify, and authenticate for a given sample of research subjects. Thus, it is often challenging to discern its specific effects in order to satisfy the scientific method of causal inferences that underlies evidence-based medicine.

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Replacement therapy for vitamin B12 deficiency: comparison between the sublingual and oral route.

Br J Clin Pharmacol

December 2003

Recanati Center for Medicine and Research and Clinical Pharmacology Unit, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Aims: To compare the efficacy of sublingual and oral administration of 500 micro g of cobalamin in subjects with cobalamin deficiency.

Materials And Results: Thirty subjects with low serum concentrations of cobalamin participated in the study. Subjects were randomly allocated to receive one tablet daily of 500 micro g cobalamin sublingually or orally, or two tablets daily of a vitamin B complex.

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Do therapeutic doses of acarbose alter the pharmacokinetics of digoxin?

Isr Med Assoc J

October 2002

Recanati Center for Medicine and Research, Clinical Pharmacology Unit, Rabin Medical Center, Beilinson Campus, Petah Tiqva, Israel.

Background: Acarbose has become an important adjuvant therapy for diabetic patients. Many of these patients are also treated with digoxin for congestive heart failure or chronic atrial fibrillation.

Objective: To evaluate a possible drug interaction between acarbose and digoxin.

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Fixed-dose combination therapy in the United States, Britain and Israel.

Isr Med Assoc J

August 2001

Recanati Center for Medicine and Research and Clinical Pharmacology Unit, Rabin Medical Center (Beilinson Campus), Petah Tiqva, Israel.

Background: Fixed dose combination therapy varies among countries.

Objective: To compare the list of fixed-dose combination therapies used in the USA, UK and Israel.

Methods: The total list of drugs and FDC drugs were counted manually from a list of generic names.

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Acute hepatitis A: combination of the relapsing and the cholestatic forms, two rare variants.

Am J Med Sci

June 2000

Recanati Center for Medicine and Research, Rabin Medical Center, Petach-Tikva, Israel.

Here we present an unusual case of a 23-year-old, otherwise healthy man who had a biphasic form of viral hepatitis A with a combination of two variants, the relapsing and cholestatic forms. One month after resolution of the first phase of acute hepatitis A, he was readmitted with jaundice and intense pruritus. During hospitalization, his serum bilirubin level increased to 50.

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