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Article Synopsis
  • Esophageal cancer is very rare in pregnant women, making up only 0.07%-0.1% of malignant tumors during pregnancy, and it progresses quickly, demanding prompt treatment.
  • A case study details a 30-year-old woman diagnosed with squamous cell carcinoma at 32 weeks of pregnancy after experiencing symptoms like hoarseness, dysphagia, and weight loss; the cancer metastasized to her parathyroid region and resulted in significant esophageal dilation.
  • After giving birth, the patient began a chemotherapy treatment plan; her follow-up imaging showed changes in her tumor, highlighting the necessity for vigilance in pregnant patients presenting with symptoms indicative of esophageal cancer.
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Key Clinical Message: Immunosuppression from B-acute lymphoblastic leukemia (B-ALL) chemotherapy and a preceding COVID-19 infection may predispose patients to rare complications such as rhino-orbital mucormycosis. Hence, a high index of suspicion should be maintained by physicians (and oncologists) if patients undergoing B-ALL treatment present with orofacial symptoms and ophthalmological manifestations such as peri-orbital swelling, ophthalmoplegia, and loss of vision, suggestive of infection.

Abstract: Mucormycosis is a severe fungal infection that poses significant mortality and morbidity risks, particularly in immunocompromised individuals.

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