18,450 results match your criteria: "Reactive Arthritis"
ACS Appl Mater Interfaces
December 2024
National Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu 610064, China.
Excessive reactive oxygen and nitrogen species (RONS) accumulation in joints are significant variables that affect the course of rheumatoid arthritis (RA). Scavenging of RONS to remodel macrophage homeostasis is a potentially powerful treatment for RA. Here, a visualized "nanosweeper" by functionalizing ultrasmall Gd/FeO nanoparticles with thiol-polyethylene glycol-phosphoric acid and 2-(3-(2-aminophenyl)ureido) ethyl methacrylate hydrochloride (APUEMA), namely GIA NPs, can simultaneously scavenge both nitric oxide (NO) and reactive oxygen species (ROS), as well as enhance magnetic resonance imaging (MRI) for the diagnosis and therapy of RA.
View Article and Find Full Text PDFCureus
November 2024
Department of Community Medicine, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai, IND.
Background The rising prevalence of osteoarthritis (OA) will create significant challenges for low-resource public health systems in countries like India, leading to increased disability and reduced quality of life. Limited access to imaging and specialized orthopedic care in rural areas often delays diagnosis and treatment until the disease has progressed to advanced stages, further burdening the economy. Objectives To estimate the community prevalence and assess the risk factors associated with OA among adults aged 40 and older in rural areas of South India and to determine their functional assessment among OA-diagnosed patients.
View Article and Find Full Text PDFBackground: In April 2024, our hospital confirmed a rare case of intra-abdominal infection by Kodamaea ohmeri. The patient sought medical attention at our hospital after taking painkillers orally for one month, experiencing recurrent abdominal pain for 17 days and worsening for 7 days. In March 2024, the patient received symptomatic treatment with oral analgesics (diclofenac sodium) for arthritis.
View Article and Find Full Text PDFCureus
November 2024
Department of Pediatrics, Japanese Red Cross Wakayama Medical Center, Wakayama, JPN.
() is a Gram-negative pathogen associated with gastrointestinal infections, such as enterocolitis. While complications like reactive arthritis can occur, progression to myositis is extremely rare. This report describes a five-year-old boy who developed myositis following a infection.
View Article and Find Full Text PDFACR Open Rheumatol
December 2024
Jefferson Einstein Hospital, Philadelphia, Pennsylvania.
Objective: The aim of this study was to investigate the impact of estrogen and progesterone analog supplementation on the development of autoimmune conditions.
Methods: This retrospective observational study used data from the TriNetX network, which comprised over 100 million patients from 89 health care organizations. We compared patients exposed to estrogen and progesterone analogs to those exposed to progesterone-only therapy, using 1:1 propensity score matching based on age, ethnicity, and additional criteria.
Mod Rheumatol
December 2024
Division of Rheumatology, Department of Internal Medicine, Keio University, Tokyo, Japan.
Objectives: We characterised early changes in laboratory parameters in Japanese patients with rheumatoid arthritis (RA) and assessed whether these changes at Month (M)1 were predictive of tofacitinib efficacy at M3.
Methods: This post hoc analysis included data from Japanese patients with RA receiving tofacitinib or placebo pooled from two Phase (P)2 studies in Japan (NCT00603512; NCT00687193) and one global P3 study (NCT00847613). Outcomes: changes from baseline in laboratory parameters (Week 2 and M1/3); efficacy endpoints (Disease Activity Score in 28 joints, based on C-reactive protein [DAS28-4(CRP)], DAS28-4, based on erythrocyte sedimentation rate [DAS28-4(ESR)], and American College of Rheumatology-N index) at M3.
FASEB J
December 2024
State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.
Mycoplasma bovis has emerged as a significant pathogen in cattle, leading to considerable economic losses in the cattle industry. It is associated with various clinical syndromes, including pneumoniae, mastitis, and arthritis. The innate immune response, particularly macrophages, plays a crucial role in combating infections caused by such pathogens.
View Article and Find Full Text PDFEur J Rheumatol
November 2024
Department of Nursing and Rehabilitation Sciences, Showa University, Tokyo, Japan.
Objective: Rheumatoid arthritis (RA) is associated with depression in approximately 15% of patients, most of whom have been studied using questionnaires. As the depression questionnaire includes questions about physical symptoms, caution should be exercised when interpreting the results due to an underlying disease. In addition, few studies have been conducted on other psychiatric disorders.
View Article and Find Full Text PDFEur J Case Rep Intern Med
November 2024
Department of Internal Medicine, Tower Health, Reading Hospital, West Reading, USA.
Introduction: Rheumatoid pachymeningitis and optic neuritis are rare complications of rheumatoid arthritis (RA) and are a diagnosis of exclusion.
Case Description: A 75-year-old male with a history of seronegative RA presented to the emergency department with left eye pain and blurry vision lasting two days. He had been diagnosed with seronegative RA around nine months previously.
Clin Pharmacol Ther
December 2024
Translational Medicine and Clinical Pharmacology, Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, Connecticut, USA.
Antibody-based therapeutic proteins (TPs) emerged as a promising therapeutic modality for chronic inflammatory diseases. During clinical development, the impact of disease on pharmacokinetics (PK) should be carefully considered to reliably extrapolate PK from healthy volunteers (HVs) in early-phase studies to patients in later-phase studies. This paper aimed to provide an overview of the impact of chronic inflammatory diseases on the PK of antibody-based TPs.
View Article and Find Full Text PDFSemin Arthritis Rheum
October 2024
Department of Rheumatology, St George Hospital, Australia; University of New South Wales, School of Public Health and Community Medicine, Australia.
Arthritis Res Ther
December 2024
Epidemiology and Health Services Research, German Rheumatology Research Center, Charitéplatz 1, 10117, Berlin, Germany.
Background: To investigate the association between the development of incident interstitial lung disease (ILD) in patients with rheumatoid arthritis (RA) and the disease activity of RA with its various components, especially C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR).
Methods: We analysed data from RA patients, observed in the German biologics register RABBIT between 2001 and 2021. In a nested case-control study, patients with a reported incident ILD diagnosis during follow-up were matched 1:5 to patients without ILD.
J Inflamm Res
November 2024
Council of Scientific & Industrial Research (CSIR), Institute of Genomics and Integrative Biology, Delhi University Campus, Delhi, 110007, India.
JAMA
December 2024
Division of Arthritis and Rheumatic Diseases (OP09), Oregon Health & Science University, Portland.
Nat Commun
December 2024
Immunity and Cancer Laboratory, Francis Crick Institute, London, UK.
Hum Immunol
December 2024
Department of Internal Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan, Republic of Korea. Electronic address:
J Inflamm Res
November 2024
Department of Interventional Radiology and Neuroradiology, Medical University of Lublin, Lublin, Poland.
J Immunol Res
December 2024
School of Basic Medicine, Guizhou University of Traditional Chinese Medicine, Guiyang 550025, China.
Z Rheumatol
December 2024
Klinik für internistische Rheumatologie, Rotes Kreuz Krankenhaus, St.-Pauli-Deich 24, 28199, Bremen, Deutschland.
Open Access Rheumatol
November 2024
Department of Biomedical Laboratory Sciences, School of Health Sciences, College of Medicine and Health Sciences, University of Rwanda, Kigali, 3286, Rwanda.
Cureus
October 2024
Internal Medicine, Hospital São Teotónio, Viseu, PRT.
J Tradit Chin Med
December 2024
Department of Traditional Chinese Medicine Rheumatology, China-Japan Friendship Hospital, Beijing 100029, China.
Exp Cell Res
November 2024
Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, 710004, China. Electronic address:
Odontology
November 2024
Department of Oral Surgery, Pathology, and Clinical Dentistry, School of Dentistry, Universidade Federal de Minas Gerais, Av. Pres. Antônio Carlos, 6627, Room 3204, Belo Horizonte, Minas Gerais, Brazil.
J Ethnopharmacol
January 2025
College of Food Science and Pharmaceutical Engineering, Zaozhuang University, Zaozhuang, 277160, China. Electronic address: