4 results match your criteria: "Rambam Medical Center and B. Rappaport Faculty of Medicine-Technion[Affiliation]"
Neuroanatomical pattern of mitochondrial complex I pathology varies between schizophrenia, bipolar disorder and major depression.
PLoS One
December 2008
Laboratory of Psychobiology, Department of Psychiatry Rambam Medical Center and B. Rappaport Faculty of Medicine Technion, Haifa, Israel.
Background: Mitochondrial dysfunction was reported in schizophrenia, bipolar disorderand major depression. The present study investigated whether mitochondrial complex I abnormalities show disease-specific characteristics.
Methodology/principal Findings: mRNA and protein levels of complex I subunits NDUFV1, NDUFV2 and NADUFS1, were assessed in striatal and lateral cerebellar hemisphere postmortem specimens and analyzed together with our previous data from prefrontal and parieto-occipital cortices specimens of patients with schizophrenia, bipolar disorder, major depression and healthy subjects.
Cerebral glucose utilization and platelet mitochondrial complex I activity in schizophrenia: A FDG-PET study.
Prog Neuropsychopharmacol Biol Psychiatry
May 2007
Laboratory of Psychobiology, Department of Psychiatry, Rambam Medical Center and B. Rappaport Faculty of Medicine Technion IIT, Haifa, Israel.
Altered cerebral energy metabolism and mitochondrial dysfunction in periphery and in brain are implicated in the pathophysiology of schizophrenia. This study investigated whether cerebral glucose metabolism (rCGM) abnormalities are linked to altered mitochondrial complex I activity in the periphery, in schizophrenia. Sixteen schizophrenic patients, 8 with total positive PANSS score >or=20 (high positive schizophrenics; HPS), and 8 with total positive score
Increased emotional distress in daughters of breast cancer patients is associated with decreased natural cytotoxic activity, elevated levels of stress hormones and decreased secretion of Th1 cytokines.
Int J Cancer
July 2002
Department of Immunology, Rambam Medical Center and B. Rappaport Faculty of Medicine-Technion, Haifa, Israel.
Article Synopsis
- Individuals at high risk for breast cancer (DBC) experience significant emotional distress, which is linked to increased levels of stress hormones.
- In a study comparing DBCP with healthy controls, DBCP showed lower natural cell activity (NCA) and immune responses when exposed to cancer cell lines.
- The findings suggest a strong correlation between emotional distress, stress hormone levels, and compromised immune functions, highlighting the potential benefits of stress-reduction interventions to lower breast cancer risk.
Chronic repetitive transcranial magnetic stimulation alters beta-adrenergic and 5-HT2 receptor characteristics in rat brain.
Brain Res
January 1999
Laboratory of Psychobiology, Department of Psychiatry, Rambam Medical Center and B. Rappaport Faculty of Medicine Technion, P.O. Box 9649, Haifa 31096,
Repetitive transcranial magnetic stimulation (rTMS) has been shown to affect mood in health and disease. Evidence to date has demonstrated an antidepressant potential for low- and high-frequency rTMS treatment. In animal behavioral models of depression magnetic stimulation of the brain induced similar effects to those of electroconvulsive shock (ECS).
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