77 results match your criteria: "Rajiv Gandhi Institute of Medical Sciences[Affiliation]"

Background Thyroid surgeries have become so common that they are performed for both benign and malignant conditions of the thyroid. However, hypoparathyroidism and recurrent laryngeal nerve (RLN) injury may turn out to be a nightmare, complicating the surgical outcome. This study will, therefore, attempt to assess the complications related to different types of thyroid surgeries in order to identify the risk factors involved.

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  • Lipoprotein(a) [Lp(a)] is recognized as a key independent risk factor for atherosclerotic cardiovascular disease (ASCVD), prompting research into various lipid-lowering drugs that might reduce its levels.
  • A systematic review of 29 studies showed that traditional lipid-lowering agents like statins and fibrates generally do not significantly affect Lp(a) concentrations, whereas Lp(a) apheresis and PCSK-9 inhibitors were effective.
  • Emerging RNA-targeting therapies, such as anti-sense oligonucleotides, demonstrated promise in lowering Lp(a) levels, but it's still unclear if these reductions will lead to fewer cardiovascular events in patients.
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Background: A plethora of studies have reported the adverse psychiatric outcomes among the general masses during the COVID-19 pandemic; however, not much data is available in relation to the Indian population from this perspective. The aim of the present study was to investigate the impact of the COVID-19 pandemic on the mental health status among the general masses in the Indian population.

Materials And Methods: The present study was planned in a cross-sectional study design between July 2020 and October 2021 in which a well-structured questionnaire, consisting of questions assessing the sociodemographic profile, while, also, specific questions related to the stress and anxiety-related variables, was used.

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Stroke is a medical condition that results from a decreased or completely diminished supply of blood to the brain, and it is considered one of the major causes of morbidity and mortality globally. Stroke is categorized as ischemic and hemorrhagic stroke, both of which demand prompt and particular timely intervention. This extensive review is done to investigate the precise management of acute and chronic manifestations of stroke in relation to neurosurgical interventions, ultimately providing a thorough analysis regarding indications, procedures, outcomes, and complications that are associated with it.

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Background: Cardiac manifestations are infrequently reported in association with celiac disease, but clear link has not been established. The aim of this study was to explore the connection of dilated cardiomyopathy in celiac disease. This systematic review also provides a comprehensive overview of the association between celiac disease and various cardiac manifestations with pathophysiology and management.

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  • Budd-Chiari syndrome (BCS) is a liver disease caused by the blockage of hepatic veins, mainly linked to blood disorders and hypercoagulable states, with improved early diagnosis and treatments reducing mortality.
  • The study analyzed gender trends in authorship of research articles on BCS from 2013 to 2022 using the PubMed database, revealing a significant imbalance with more male authors (68.2%) than female authors (31.8%).
  • The findings highlight the ongoing gender disparities in academic publishing, emphasizing the need for awareness and efforts to promote equity in research contributions and healthcare systems.
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Background: Tuberculosis (TB) remains the number one cause of adult deaths by a curable infectious disease. bacilli (MTB) is the most common causative organism isolated from mycobacterial lymphadenitis. Accurate and speedy diagnosis is required, especially in paucibacillary extrapulmonary TB.

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Background The ability to perceive sound is crucial for effective communication and environmental awareness. This study aimed to assess sensorineural hearing loss (SNHL) in patients with both diabetes mellitus (DM) and hypertension (HTN). Materials and methods A total of 120 participants of both genders were divided into three groups: Group I consisted of diabetic patients (n=40, 22 males and 18 females), Group II included hypertensive individuals (n=40, 16 males and 24 females), and Group III served as controls (n=40, 15 males and 25 females).

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Background: Artificial intelligence (AI) has led to the development of various opportunities during the COVID-19 pandemic. An abundant number of applications have surfaced responding to the pandemic, while some other applications were futile.

Objectives: The present study aimed to assess the perception and opportunities of AI used during the COVID-19 pandemic and to explore the perception of medical data analysts about the inclusion of AI in medical education.

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Background Intracapsular femoral neck fractures account for a majority of hip fractures. This study aimed to investigate the efficacy of valgus osteotomy as a primary treatment for intracapsular femoral neck fractures in adult patients aged 15-60 years, assessing its impact on functional outcomes and fracture union. Methodology A retrospective clinical analysis was conducted at the Department of Orthopedics and Traumatology, Osmania Government General Hospital, Hyderabad, India, focusing on patients treated with primary intertrochanteric valgus osteotomy for intracapsular femoral neck fractures.

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  • Dermatophytosis is a common fungal infection that requires antifungal treatment, and amorolfine is a new topical option available as a cream or lotion.
  • A clinical trial involving 284 patients compared the efficacy and safety of amorolfine lotion and cream, finding that both formulations led to high cure rates after four weeks of treatment.
  • The study concluded that the lotion was just as effective and safe as the cream, with mild and manageable side effects reported for both treatments.
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Patterned hair loss (PHL) is a severe hair condition that affects both sexes. Mesotherapy is a treatment that involves microinjecting medications and/or vitamins into the middle layer of the skin. Mesotherapy reduces systemic adverse effects by delivering drugs directly to the hair follicle, increasing local bioavailability while lowering systemic exposure.

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Inflammatory bowel disease (IBD), comprising Crohn's disease (CD) and ulcerative colitis (UC), is characterized by chronic intestinal inflammation. The dysbiotic gut microbiome likely contributes to IBD pathogenesis. Microbiome-directed therapies such as fecal microbiota transplantation (FMT), probiotics, and synbiotics may help induce and maintain remission.

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Acne vulgaris, commonly called acne, is a skin condition affecting many individuals globally. It is a chronic condition characterized by developing pimples, blackheads (open comedones), whiteheads (closed comedones), and other skin lesions. Acne usually appears on the face, neck, chest, and back.

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An idiopathic condition known as inflammatory bowel disease (IBD) is characterized by a dysregulated immune response to the intestinal flora of the host. It falls into one of two primary categories: ulcerative colitis or Crohn's disease. A wide range of disorders, both clinically and genetically, can cause IBD.

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Thyroid gland dysfunction (TGD) has been increasingly recognized as a potential comorbidity in patients with chronic obstructive pulmonary disease (COPD). This study was designed to determine the prevalence of TGD in COPD patients. This systematic review and meta-analysis was conducted according to the guidelines of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA).

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Introduction Hemophilia is an uncommon, X-linked recessive bleeding condition characterized by a lack of either factor VIII or factor IX. It is more prevalent in men. Due to the substantial impact inhibitor development has on patient prognosis, the primary treatment for hemophilia is the transfusion of recombinant factors.

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Background and aim Monkeypox outbreaks in several nations have brought focus to the emerging virus. The clinical presentation of monkeypox is less severe than smallpox but is fairly comparable, presenting with fever, headache, lymphadenopathy, back discomfort, myalgia, and skin rashes. The misinformation spread on social platforms had a major impact on the effectiveness of outbreak control measures.

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In recent years, notable advancements have been made in managing endocrine system disorders and arrhythmias. These advancements have brought about significant changes in healthcare providers' approach towards these complex medical conditions. Endocrine system disorders encompass a diverse range of conditions, including but not limited to diabetes mellitus, thyroid dysfunction, and adrenal disorders.

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The global incidence of renal disorders is on the rise, demanding the implementation of novel and comprehensive strategies for patient care. The present study demonstrates the significance of renal health, offering a comprehensive comprehension of renal physiology and the escalating load of renal illnesses. The relevance of controlling renal illnesses is underscored by a thorough examination of conventional treatments, which encompass pharmaceutical interventions, dialysis, and transplantation.

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Asthma affects 7% of children and 8% of adults in the United States. There is a paucity of studies examining the association between passive smoking and an increased risk of asthma exacerbations that led the authors to examine the association between various modes of smoking and rates of asthma exacerbations. A retrospective cross-sectional/case-control study was conducted using the National Health and Nutrition Examination Survey dataset (2013-2018).

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Background: Keratoconjunctivitis sicca or dry eye disease (DED) is a multifactorial disorder underpinned by a complex inflammatory cycle. Introduction of topical cyclosporine has been a significant advance in the management of DED. In recent years advancements in formulation technology have led to development of micellar nano-particulate (MNP) cyclosporine formulations that promise better penetration into ocular target tissues and potential for reduced ocular surface irritation.

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Background At the peak of the coronavirus disease 2019 (COVID-19) pandemic, the need for an orally administered agent to prevent the progression of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection became increasingly evident, which was the impetus behind our investigations with molnupiravir. Molnupiravir has been shown to be effective in preventing hospitalizations and/or clinical complications in patients with mild-to-moderate COVID-19. In this study, we evaluate the efficacy and safety of molnupiravir in Indian patients with mild SARS-CoV-2 infection and at least one risk factor for disease progression (CTRI/2021/05/033739).

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Many parasitic infections essentially pose a significant public health problem throughout the world. However, the consequence of the issue is felt more among developing countries like India. This is majorly due to unsatisfactory hygienic practices and overcrowding, among others.

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