The Effect of a Yoga Lifestyle on QRISK3 Score Among Individuals at High Risk for Cardiovascular Disease.

Cardiovascular disease is a major cause of mortality and morbidity, and symptoms may not always be visible. Improved preventive strategies could reduce the burden of disease. Yoga is an accessible, affordable lifestyle modification program that has been shown to reduce cardiometabolic risk factors in individuals at high risk for cardiovascular disease.

Patterns and Determinants of Primary Tooth Extraction in Children: A Study in an Indian Tertiary Care Dental Setting.

Introduction: Preservation of primary teeth is essential for optimal oral health in children; however, there is limited research on primary tooth extraction patterns in India. This study aimed to investigate the reasons for and patterns of primary tooth extraction in children in an Indian tertiary care dental setting.

Methodology: This retrospective cross-sectional study analyzed dental records of children aged up to 14 years who underwent tooth extraction under local anesthesia from January to December 2023.

Importance of Dyslipidemias in Very Premature Coronary Artery Disease in India: A Registry-based Study.

Background And Objective: Premature coronary artery disease (CAD) is an important cause of death in India. To identify risk factors in patients with premature CAD, we performed a registry-based study.

Methods: Consecutive patients admitted for percutaneous coronary intervention (PCI) from October 2020 to June 2021 were recruited.

Restoring Oral Health: Implant-Supported Full-Mouth Rehabilitation for an Edentulous Patient.

Edentulism, the loss of all the natural teeth, significantly impacts a patient's functional, aesthetic, and psychological well-being. Traditional dentures often fail to provide the required stability and functionality. Implant-supported full-mouth rehabilitation has emerged as an advanced solution, leveraging strategically placed dental implants to support fixed prostheses that mimic natural teeth in appearance and function.

Palatogingival Groove: The Known-unknown Devourer.

Aim: This case report aims to describe the management of a maxillary lateral incisor with a palatogingival groove (PGG) associated with a complex lesion.

Background: The PGG is a rare developmental anomaly that involves the lingual surface of the maxillary incisors and extends for varying distances and depths on the root surface. This anomaly is usually inconspicuous and funnel-shaped, which forms a niche where bacterial plaque and calculus can accumulate to levels significant for pathological changes resulting in endodontic and periodontal lesions.

Don't Rush with Your Brush: An Study on Toothbrush Hygiene.

Aim: To evaluate the effectiveness of audiovisual (AV) aids in creating awareness of toothbrush hygiene.

Materials And Methods: This randomized trial study was conducted on 40 children aged 6-11 years. Children were given soft toothbrushes and then collected after brushing for 14 days.

Bioactive Milk Peptides as a Nutraceutical Opportunity and Challenges.

The biotechnology field has witnessed rapid advancements, leading to the development of numerous proteins and peptides (PPs) for disease management. The production and isolation of bioactive milk peptides (BAPs) involve enzymatic hydrolysis and fermentation, followed by purification through various techniques such as ultrafiltration and chromatography. The nutraceutical potential of bioactive milk peptides has gained significant attention in nutritional research, as these peptides may regulate blood sugar levels, mitigate oxidative stress, improve cardiovascular health, gut health, bone health, and immune responses, and exhibit anticancer properties.

Comparative Evaluation of Two Esthetic Full Coronal Restorative Materials for Primary Incisors.

Aim: This study was designed to compare the clinical efficacy of two esthetic restorative materials, nanoceramic (Magma NT®) and giomer (Beautifil II®), as full coronal restoration in primary maxillary incisors.

Materials And Methods: A total of 15 patients aged 3-5 years presenting with mutilated primary maxillary incisors due to caries or trauma were selected for the study using randomized simple sampling. A total of 40 maxillary incisors were randomly divided into two equal groups, with 20 teeth in each group.

A Study on Yoga-Based Lifestyle Intervention versus Dietary Intervention Alone on Cardiometabolic Risk Factors among People with Prediabetes.

Background: Prediabetes is presented as a metabolic state that predisposes persons to a greater risk of diabetes progression in the future. Prediabetes is an intervening stage between normoglycemia and diabetes with impaired fasting glucose and impaired glucose tolerance. This study aimed to compare the effect of the yoga-based lifestyle intervention (including diet) versus dietary intervention (DI) alone on cardiometabolic parameters namely fasting blood glucose (FBG), glycated hemoglobin (HbA1C), lipid profile; triglyceride (TG), total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), very low-density lipoprotein (VLDL), heart rate variability (HRV), and carotid intima-media thickness (CIMT) among people with prediabetes.

Item Analysis of Single Best Response Type Multiple Choice Questions for Formative Assessment in Obstetrics and Gynaecology.

Background: MCQs (multiple choice questions) can be used to assess higher-order skills and be utilised for creating a question bank.

Purpose Of Study Aim: To perform post-validation item analysis of MCQs constructed by medical faculty for formative assessment of final-year medical students and to explore the association between difficulty index ( value) and discrimination indices (DI) with distractor efficiency (DE).

Methods: An observational study was conducted involving 50 final-year MBBS students and 10 faculty members for a period of one year (October 2020 to September 2021).

A study to assess the effect of yoga and diet on Framingham risk score among high-risk cardiovascular subjects.

Introduction: Cardiovascular diseases (CVDs) are a cluster of disorders of blood vessels and the heart. As a form of physical activity, yoga postures, and pranayama have been shown to be beneficial in various health conditions, i.e.

Declining Trend in Antimicrobial Sensitivity in Respiratory Tract Bacterial Pathogens against Commonly Used Drugs at a Tertiary Care Hospital.

Objectives: Antimicrobial resistance (AMR) is a major health issue. To determine trends in bacterial organisms in respiratory tract infections (RTIs) and their antibiotic sensitivity at a tertiary care center in India, we performed this study.

Methods: Successive samples received from January 2017 to December 2021 from the respiratory tract (sputum, endotracheal secretion, and bronchoalveolar lavage) from intensive care units and medical inpatients were processed for bacterial growth.

Konjac glucomannan: A comprehensive review of its extraction, health benefits, and pharmaceutical applications.

Konjac glucomannan (KG) is a dietary fiber hydrocolloid derived from Amorphophallus konjac tubers and is widely utilized as a food additive and dietary supplement. As a health-conscious choice, purified KG, along with konjac flour and KG-infused diets, have gained widespread acceptance in Asian and European markets. An overview of the chemical composition and structure of KG is given in this review, along with thorough explanations of the processes used in its extraction, production, and purification.

Harnessing polyelectrolyte complexes for precision cancer targeting: a comprehensive review.

Polyelectrolytes represent a unique class of polymers abundant in ionizable functional groups. In a solution, ionized polyelectrolytes can intricately bond with oppositely charged counterparts, giving rise to a fascinating phenomenon known as a polyelectrolyte complex. These complexes arise from the interaction between oppositely charged entities, such as polymers, drugs, and combinations thereof.

Influence of COVID-19 pandemic in India on coronary artery disease clinical presentation, angiography, interventions and in-hospital outcomes: a single centre prospective registry-based observational study.

Objective: The study examined the influence of the COVID-19 pandemic in India on variation in clinical features, management and in-hospital outcomes in patients undergoing percutaneous coronary intervention (PCI).

Design: Prospective registry-based observational study.

Setting: A tertiary care hospital in India participant in the American College of Cardiology CathPCI Registry.

Role of opioid use in gastrointestinal obstruction and perforation: A retrospective review.

Introduction: Pain is one of the most common complaints that brings a patient to a hospital. For this, usually, the patient might have already consumed various types of pain killer combinations, either prescribed or over-the-counter. In some of these cases, a patient consumes these medicines unmonitored for a long time and then comes with complications, among which gastrointestinal tract obstruction and perforation are the most life threatening.

Pectin hydrogels for controlled drug release: Recent developments and future prospects.

Pectin hydrogels have emerged as a highly promising medium for the controlled release of pharmaceuticals in the dynamic field of drug delivery. The present review sheds light on the broad range of applications and potential of pectin-based hydrogels in pharmaceutical formulations. Pectin, as a biopolymer, is a versatile candidate for various drug delivery systems because of its wide range of properties and characteristics.

Trends in epidemiology of dyslipidemias in India.

Dyslipidemias are the most important coronary artery disease (CAD) risk factor. High total cholesterol and its principal subtypes: low-density lipoprotein (LDL) cholesterol and non-high-density lipoprotein (NHDL) cholesterol are the most important. Epidemiological and Mendelian randomization studies have confirmed role of raised triglycerides and lipoprotein(a).