Epidemiological patterns and trends of paediatric snakebites in Sri Lanka.

Objectives: This study aimed to analyse the epidemiological patterns of paediatric snake bites in Sri Lanka over a 4-year period (2020-2024).

Methods: A multi-centre, retrospective observational study was conducted from June 2020 to June 2024 across nine governmental hospitals in seven provinces of Sri Lanka. Data were collected based on 757 children presenting with snake bites.

A prospective cohort study to investigate the transmission and burden of in Sri Lanka.

Methicillin-resistant (MRSA) is a common cause of infection in both community and healthcare settings, and the household may be a central component linking these two environments. Strategies to prevent transmission and thereby reduce the risk of infection must be informed by a detailed understanding of local epidemiology. These data are typically lacking in many low- and middle-income countries.

What do women experiencing domestic violence expect from healthcare professionals? A qualitative study in Sri Lanka.

Objectives: For healthcare professionals (HCPs) to provide optimal support for women experiencing domestic violence (DV), it is important to understand what type of support women expect from HCPs. The objective of this study was to explore what kind of support women who experienced DV in Sri Lanka expect from HCPs.

Design: A qualitative descriptive design was used.

ADENOVIRUS PNEUMONITIS AND DISSEMINATED VIREMIA IN A NEONATE SUCCESSFULLY TREATED WITH STEROIDS, CIDOFOVIR AND ECMO.

A 5-day-old neonate was admitted with chest radiograph showing right-lung opacification. This, together with a severe adenovirus (AdV) viremia (11.8 million copies/mL), indicated severe adenovirus pneumonitis.

Human intestinal nematode infections in Sri Lanka: A scoping review.

Background: Sri Lanka, an island located in South Asia, once experienced a notable prevalence of human intestinal nematode infections (HINIs). With the implementation of control programs, infection prevalence was reduced. Detailed information on prevalence, distribution and temporal trends of HINIs is limited.

Situational analysis of pesticide poisoning and perceptions of autoinjector devices in rural communities in Sri Lanka - a study protocol.

Intentional and unintentional pesticide poisoning is an important public health problem, especially in low- and middle-income countries. Individuals who have been exposed to toxic pesticides, particularly organophosphorus insecticides, need early treatment. Atropine autoinjector devices offer a potential solution, allowing storage of effective treatment near agricultural workers' fields and homes that could be reached within minutes by the worker or fellow villagers to provide first-line emergency care.

Investigating disease awareness of cutaneous leishmaniasis in rural Sri Lanka to inform public health services: a cross-sectional study.

Objective: To assess community awareness of cutaneous leishmaniasis (CL) in a disease-endemic district in Sri Lanka.

Design: Population-based cross-sectional study.

Setting: This study was conducted in selected 158 Grama Niladhari divisions covering all the 22 Divisional Secretariat areas of the Anuradhapura district, Sri Lanka.

ATAK (Adrenaline, Takotsubo, anaphylaxis, and Kounis hypersensitivity-associated syndrome) following common cobra (Naja naja) bite: A case report from Sri Lanka.

A 68-year-old woman, after an Indian cobra (Naja naja) bite, developed anaphylaxis, Takotsubo cardiomyopathy, and Kounis syndrome. She was initially diagnosed with acute coronary syndrome after anaphylaxis due to exposure to cobra venom, indicating Kounis syndrome. The echocardiogram, electrocardiogram, and almost complete reversal of dyskinetic myocardium established Takotsubo cardiomyopathy.

Assessment of the productivity loss due to leading maternal ill-health conditions: a follow-up study of a prospective pregnancy cohort in rural Sri Lanka.

Objectives: This study aimed to assess the productivity loss and cost due to maternal ill-health conditions and its associated factors throughout pregnancy in rural Sri Lanka.

Design: A follow-up study of women registered in the Rajarata Pregnancy Cohort (RaPCo).

Setting: Anuradhapura district, Sri Lanka.

Exploring Fungal Diversity in Seagrass Ecosystems for Pharmaceutical and Ecological Insights.

Marine ecosystems are important in discovering novel fungi with interesting metabolites that have shown great potential in pharmaceutical and biotechnological industries. Seagrasses, the sole submerged marine angiosperm, host diverse fungal taxa with mostly unknown metabolic capabilities. They are considered to be one of the least studied marine fungal habitats in the world.

A real-world study of BBIBP-CorV vaccine effectiveness in a Sri Lanka rural province.

Objective: Real-world studies assessing the effectiveness of the BBIBP-CorV vaccine in low and middle-income countries are limited. We evaluated the BBIBP-CorV vaccine's effectiveness in reducing COVID-19 symptomatic disease, hospitalisation, severe disease, and mortality during the third wave of the pandemic in Sri Lanka.

Methods: We conducted a test-negative case-control study in North Central Province from May 2021 to February 2022.

Do National Nutrition Policies Relevant to Sri Lankan Adolescents Effectively Uplift Their Development and Well-Being? A Qualitative Study.

Adolescence is a crucial phase of growth and development in the life course, and healthy nutrition is essential during this period. The objective of this study was to explore the perceptions regarding the implementation of relevant nutrition policies for adolescents in Sri Lanka. The study is qualitative, employing a "phenomenology" approach.

Empowering communities to use healthy lifestyle centres: an implementation research from Sri Lanka.

Objective: Healthy lifestyle centres (HLCs), a state service that screens for major non-communicable disease (NCD) risk factors and promotes lifestyle modifications in Sri Lanka, report underutilisation. The study aimed to assess the effectiveness of a participatory intervention to empower communities in improving HLC utilisation.

Design: A quasi-experimental study based on the principles of community-based participatory research SETTING: Six rural communities each as the intervention (IG) (Gampaha district) and comparison (CG) groups (Kalutara district) from the capital province of Sri Lanka.

A shotgun proteomic dataset of human mucosal-associated invariant T cells.

Mucosal-associated invariant T (MAIT) cells represent a unique unconventional T cell population important in eliciting immunomodulatory responses in a range of diseases, including infectious diseases, autoimmunity and cancer. This innate-like T cell subset predominantly express CD8 in humans. Unlike conventional CD8 T cells, which recognize peptide antigen presented by polymorphic major histocompatibility complex (MHC) molecules, MAIT cells are restricted by MR1, a non-polymorphic antigen-presenting molecule widely expressed in multiple tissues.

pyelonephritis in a young adult with ureteric calculus: case report.

Introduction: is a Gram-positive coccobacillus, and a member of the normal human microbiota. is considered as an emerging pathogen causing urinary tract infections among the elderly. Because of an anaerobic growth requirement and lack of knowledge on pathogenic potential following conventional microbiology laboratory techniques, is difficult to identify.

Exploring the relationship between the food environment and preferences among schoolchildren in a low socioeconomic community in Sri Lanka: A GIS-based assessment.

The food environment in school neighborhoods plays a crucial role in manipulating the food choices of schoolchildren. This study investigated the relationship between the food environment in neighborhoods and the dietary practices of government school students in a low socioeconomic setting in Sri Lanka. This cross-sectional study surveyed the neighborhood food environment of selected schools (n = 30) in the Monaragala District, Sri Lanka, using geographical information system (GIS) data and collected dietary information from a representative sample of schoolchildren (n = 603).

Exploring the Association Between Behavioural Modification in Response to the Prevailing Economic Crisis and Mental Health Outcomes of Nurses from Teaching Hospitals, Sri Lanka.

Introduction: The nursing profession is a cornerstone in the healthcare workforce. Yet, it remains vulnerable to severe mental health challenges, stemming from a complex interplay of social and occupational factors. It is evident that crisis situations have profound influence on the mental-wellbeing of nurses.

Utility of Three Serum Biomarkers for Early Detection of Systemic Envenoming Following Viper Bites in Sri Lanka.

Study Objective: Early detection of systemic envenoming is critical for early antivenom therapy to minimize morbidity and mortality from snakebite. We assessed the diagnostic utility of 3 serum biomarkers in the early detection of systemic envenoming in viper bites in rural Sri Lanka.

Methods: All confirmed snakebite patients admitted to Teaching Hospital Anuradhapura from July 2020 to June 2021 were included.