The interaction of Suk-Saiyasna remedy with GABAA and CB1 receptor-targeting drugs: Enhancing hypnotic and sedative effects in models.

The Suk-Saiyasna remedy, an herbal treatment, was historically used but ceased due to its cannabis content. After a relaxation of drug control laws in Thailand, its use re-emerged. This study examines the Suk-Saiyasna remedy's impact on rodent behavior and its receptor effects.

Innovative Electrospun Nanofiber Mats Based on Polylactic Acid Composited with Silver Nanoparticles for Medical Applications.

Nanofibers are some of the most attractive materials that can modify functionalities for developing new kinds of specific applications and are mainly used as a biomedical material. Herein, we designed and prepared antibacterial nonwoven fiber mats of PLA and PLA composited with Ag nanoparticles by electrospinning. The effects of varying filler contents on their chemical, surface morphology, thermal, water absorbency, and antibacterial properties were investigated using FTIR, SEM/EDS, DSC, swelling ratio, and qualitative and quantitative antibacterial tests.

Impacts of pre-treatment methods on the morphology, crystal structure, and defects formation of hydroxyapatite extracted from Nile tilapia scales.

The comprehensive control of hydroxyapatite (HAp), involving morphological and structural variations, particle sizes, and defect formations, has garnered considerable attention for its versatile functionalities, rendering it applicable in diverse contexts. This work examined the shape, structure and optical characteristics, and defect formation in hydroxyapatite (HAp) extracted from Nile tilapia () scales with various pre-treatments through experiments and density functional theory (DFT) calculations. Utilizing scanning electron microscopy, our findings revealed that dried fish scales (FS-D) exhibited a layered pattern of collagen fibers, while boiled fish scales (FS-B) had smoother surfaces and significantly reduced collagen content.

Current-Mode Shadow Filter with Single-Input Multiple-Output Using Current-Controlled Current Conveyors with Controlled Current Gain.

In this paper, a novel current-mode shadow filter employing current-controlled current conveyors (CCCIIs) with controlled current gains is presented. The CCCII-based current-mode shadow filters are resistorless and can offer a number of advantages such as circuit simplicity and electronic tuning capability. The proposed shadow filters offer five filtering functions, i.

Raw starch degrading alkaline α-amylase from Geobacillus kaustophilus TSCCA02: Production, characterization, and its potential for application as a detergent additive.

Geobacillus kaustophilus TSCCA02, a newly isolated strain from cassava (Manihot esculenta L.) rhizosphere soil in Thailand, showed maximum raw starch degrading enzyme (RSDE) activity at 252.3 ± 9.

Optimization of Thermoplastic Pultrusion Parameters of Jute and Glass Fiber-Reinforced Polypropylene Composite.

Thermoplastic pultrusion is a suitable process for fabricating continuous unidirectional thermoplastics with a uniform cross-section, high mechanical properties due to continuous fiber reinforcement, low cost, and suitability for mass production. In this paper, jute and glass fibers were reinforced with a polypropylene matrix and fabricated using the thermoplastic pultrusion process. The volumetric fraction of the composite was designed by controlling the filling ratio of the reinforcing fiber and matrix.

Gamma Irradiation Promotes the Growth Rate of Thai Pigmented Rice As Well As Inducing the Accumulation of Bioactive Compounds and Carbohydrate Hydrolyzing Enzymes Inhibitors (α-Glucosidase and α-Amylase) under Salt Conditions.

Rice contains many bioactive compounds that perform various biological activities. Some of these compounds have been identified as α-glucosidase and α-amylase inhibitors, including guaiacol, vanillin, methyl vanillate, vanillic acid, syringic acid, and 2-pentyl furan. In this study, we assessed the growth rate, photosynthetic pigment content, phenolic content, and flavonoid content of gamma-irradiated Thai pigmented rice.

Poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) as an insulin carrier in silk fibroin hydrogels for transdermal delivery iontophoresis.

In this study, silk fibroin (SF) was utilized as the starting material to fabricate physically crosslinked hydrogels. Poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) was synthesized and characterized as a drug carrier, with insulin as the model drug. PEDOT:PSS, with a high electrical conductivity of 1666 ± 49 S cm, interacted with insulin molecules electrostatic interaction by replacing the dopant PSS molecules.

Impact of pretreatment with dielectric barrier discharge plasma on the drying characteristics and bioactive compounds of jackfruit slices.

Background: Hot-air drying is a popular method for preserving the production of jackfruit, but heat treatment damages its nutritional qualities. Cold plasma is one of the pretreatment methods used to preserve quality attributes of fruits before drying. In the present work, we studied the effect of dielectric barrier discharge (DBD) plasma on the drying characteristics, microstructure, and bioactive compounds of jackfruit slices with different pretreatment times (15, 30, 45, and 60 s), followed by hot-air drying at 50, 60, and 70 °C.

Asiatic acid-entrapped transfersomes for the treatment of hypertrophic scars: In vitro appraisal, bioactivity evaluation, and clinical study.

Non-invasive treatment options for hypertrophic scars (HTS) are limited, and treating HTS remains challenging due to their unappealing appearance and associated social stigma. In this work, a novel transfersomal system named Asiatic acid-entrapped transfersomes (AATs) was prepared. AATs were evaluated for their skin permeability, anti-inflammatory activity, and other characteristic parameters to determine the most promising formulation.

Pre-exposure Prophylaxis Adherence Among Men Who Have Sex With Men: A Systematic Review and Meta-analysis.

Objectives: The effectiveness and efficiency of pre-exposure prophylaxis (PrEP) in reducing the transmission of human immunodeficiency virus (HIV) among men who have sex with men (MSM) relies on how widely it is adopted and adhered to, particularly among high-risk groups of MSM. The meta-analysis aimed to collect and analyze existing evidence on various factors related to PrEP adherence in MSM, including demographic characteristics, sexual behaviors, substance use, and psychosocial factors.

Methods: The meta-analysis followed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines.

Prevalence, virulence characteristics, and antimicrobial resistance of Vibrio parahaemolyticus isolates from raw seafood in a province in Northern Thailand.

Vibrio parahaemolyticus (V. parahaemolyticus) is commonly found in seawater and seafood products, but evidence is limited of its presence in seafood marketed in locations very distant from coastal sources. This study determined the prevalence and characterization of V.

Elucidation of the Catalytic Pathway for the Direct Conversion of Furfuryl Alcohol into γ-Valerolactone over AlO-SiO Catalysts.

The one-pot conversion of furfuryl alcohol (FA) into GVL was investigated over the sol-gel-synthesized AlO-SiO (AlSi) catalysts with various AlO loadings (0.2-10 wt %) and commercial zeolites including MFI-1, H-ZSM5, H-beta, and HY-15 in a batch reactor under mild reaction conditions (130 °C, 1 bar N, and 15-120 min). The reaction pathways depend largely on the acid properties of the catalysts, especially the types of Bronsted (B) and Lewis (L) acid sites.

A highly sensitive and selective rhodamine-semicarbazide based fluorescent sensor for Cu detection in real water samples and fluorescence bioimaging in HepG2 cells.

A colorimetric and fluorescent sensor, selective for Cu ions, was synthesized in two steps using a rhodamine-based compound attached to the semicarbazide-picolylamine moiety (RBP). Spectroscopic measurements, including UV-Vis absorption and fluorescence emission, were conducted in the semi-aqueous medium containing acetonitrile/4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid, denoted as MeCN/HEPES buffer (2:8, v/v, pH 7.0).

Genomic Selection Using Single-Step Genomic BLUP on the Number of Services per Conception Trait in Thai-Holstein Crossbreeds.

Reproductive traits are important traits that directly affect a farmer's income and are difficult to improve upon using traditional genetic methods. Therefore, there is a need to consider new options for increasing the accuracy of the genetic selection of dairy cows. The objective of this study was to compare the genetic methods of the traditional BLUP and ssGBLUP techniques in terms of the estimated genetic parameters and accuracy of the estimated breeding values.

A highly sensitive hyperbranched Au plasmonic blackbody immunochromatographic assay for detection of leucomalachite green in fish and shrimp.

A novel immunochromatographic assay (ICA) based on hyperbranched Au plasmonic blackbodies (AuPBs) with a smartphone readout was fabricated for the detection of leucomalachite green (LMG) in fish and shrimp products. The ICA was carried out in a competitive immunoassay format with AuPBs as labels. The developed AuPBs-ICA allowed for the LMG detection with a low detection limit (0.

Melt Spinning Process Optimization of Polyethylene Terephthalate Fiber Structure and Properties from Tetron Cotton Knitted Fabric.

Polyester/cotton fabrics with different proportions of Tetron Cotton, TC (35% Cotton/65% PET), and Chief Value Cotton, CVC (60% Cotton/40% PET), were investigated by removing the cotton component under various phosphoric acidic conditions including the use of cellulase enzymes. The remaining polyethylene terephthalate (PET) component was spun using the melt spinning method. Only 85% HPO-Enz_TC could be spun into consistent filament fibers.

Influence of Dose, Particle Size and Concentration on Dermal Penetration Efficacy of Curcumin.

The influence of size, particle concentration and applied dose (finite vs. infinite dose) on the dermal penetration efficacy of curcumin was investigated in this study. For this, curcumin suspensions with different particle sizes (approx.

Microencapsulation of Mitragyna leaf extracts to be used as a bioactive compound source to enhance in vitro fermentation characteristics and microbial dynamics.

Objective: Mitragyna speciosa Korth is traditionally used in Thailand. They have a high level of antioxidant capacities and bioactive compounds, the potential to modulate rumen fermentation and decrease methane production. The aim of the study was to investigate the different levels of microencapsulated-Mitragyna leaves extracts (MMLE) supplementation on nutrient degradability, rumen ecology, microbial dynamics, and methane production in an in vitro study.

Assessment of in vitro anti-skin aging activities of Phyllanthus indofischeri Bennet extracts for dermatological and aesthetic applications.

Giant Indian Gooseberry (GIG) or Phyllanthus indofischeri Bennet are commercially cultivated and commonly used herbs in Traditional medicine, especially in Thailand. The aim of this study was to assess the potential of the GIG extracts in anti-aging activities to be a dermatological application. The juice, meat residues, and seeds of GIG collected from Sra Kaeo Province, Thailand, were extracted by the Boiling method (B) and the Maceration process (M) by using 95% ethanol as a solvent.

Effect of cyanide-utilizing bacteria and sulfur on feed utilization, microbiomes, and cyanide degradation in cattle supplemented with fresh cassava root.

This study aimed to compare the effects of adding cyanide-utilizing bacteria (CUB) and sulfur on rumen fermentation, the degradation efficiency of hydrogen cyanide (HCN), feed utilization, and blood metabolites in beef cattle fed two levels of fresh cassava root (CR). A 2 × 2 factorial arrangement in a 4 × 4 Latin square design was used to distribute four male purebred Thai native beef cattle (2.5-3.

In Vitro Antimicrobial Activity of (Pink Water Lily) Leaf Extracts.

This research comparatively investigates the in vitro antimicrobial activity of extracts from (pink water lily) leaves against pathogenic bacteria. The experimental extracts are aqueous, acetonic, and 95% ethanolic extracts; and the pathogenic bacteria being studied include , , , and , which are commonly found in freshwater fish and brackish aquatic animals. The ethanolic extract achieves the highest bacterial inhibitory effects against and .

Green one-step synthesis of mushroom-derived carbon dots as fluorescent sensors for Fe detection.

Blue photoluminescent carbon dots were synthesized from Lèv. a simple hydrothermal process without additional chemical reagents or functionalization. The carbon dots (hereafter referred to as LCDs) were quasi-spherical with an average diameter of 6.

Enhancing melon growth and sustainability through spun-bonded polypropylene fabric wrapping.

This study aimed to assess various weights of spun-bonded nonwoven polypropylene (PP) fabrics for wrapping outdoor-grown melons, providing cost-effective options for both construction and insect protection. Fruit wrap bags were crafted using different materials, and spun-bond fabrics with weights of 30, 40, 50, and 60 gsm were tested for encasing melons. The results demonstrated that the 50 gsm spun-bonded bags significantly improved melon growth after a four-week period, establishing them as the preferred choice for outdoor melon cultivation.

Investigation on the physical properties and biocompatibility of zirconia-alumina-silicate@diopside composite materials and its toxicity study in embryonic zebrafish.

Bioceramic materials have a wide range of applications in the biomedical field, such as in the repair of bone defects and dental surgery. Silicate-based bioceramics have attracted biomedical researchers' interest due to their bioactivity and biodegradability. In this study, extended the scope of ZAS utilization in bone tissue engineering by introducing calcium-magnesium-silicate (diopside, CMS) as an interface material aim to develop a machinable bioceramic composite (ZASCMS) by the sol-gel method.