A challenging transseptal mitral valve in valve case report: Success and safety.

Key Clinical Message: Transcatheter mitral valve implantation (TMVI) is considered a less-invasive approach than open-heart surgery, favored in high-risk patients elected for valve replacement. Although seemingly suitable, this procedure is highly operator-dependent.

Abstract: Transcatheter mitral valve implantation (TMVI) is an alternative in high-risk patients.

Multimodality imaging in the diagnostic approach to a patient with carcinoid heart disease involving four heart valves.

Carcinoid heart disease is a rare condition that occurs in less than half of patients with carcinoid syndrome. The disease mainly affects right-sided heart valves; however, in 5%-10%, it can also involve left-sided valves. This case illustrates the most complicated form of the disease involving four heart valves.

The Potential Involvement of SARS-CoV-2 in the Immuno-Pathogenesis of a Type A Aortic Dissection Case.

The novel coronavirus disease 2019 (COVID-19) may represent different clinical manifestations with different severities, from mild to severe. Even though the respiratory system is the mainly involved organ, numerous reports have mentioned cardiovascular complications in COVID-19. Herein, we report a case of type A aortic dissection in a COVID-19 patient.

A case series of myocardial infarction in SARS-CoV-2-infected patients: Same complication, different outcomes.

Thrombosis is frequently observed in COVID-19, especially in critically ill patients. Management of such life-threatening conditions is of high importance in the context of the current pandemic. Herein, we provide a case series of myocardial infarction in the clinical evolution of COVID-19, emphasizing its importance and implications on the cardiovascular system.

Targeted treatment in viral-associated inflammatory cardiomyopathy.

Detection of viruses like HHV-6 in endomyocardial biopsy or serum serology of patients with myocarditis or heart failure features unresponsive to conventional heart failure therapies could be a potential targeted treatment especially in refractory cases.

Mesenchymal stem cell-derived exosomes: A novel potential therapeutic avenue for cardiac regeneration.

Coronary artery diseases (CADs) represent a significant cause of death worldwide. During recent decades the rate of cardiovascular mortality has been declined as a result of modern medicine and surgery. However, despite the fact that cardiac cells, including cardiomyocytes (CMCs), vascular smooth muscle cells (VSMC) and vascular endothelial cells (VEC), can be regenerated by cardiac adult stem cell, the regenerative capacity of these cells are limited and inadequate to functionally regenerate heart damaged tissue.