[Clinical and surgical gender differences in patients older than 75 years who underwent emergency percutaneous coronary intervention in acute myocardial infarction].

Unlabelled: There were 85 cases of endovascular treatment of acute myocardial infarct (AMI) in patients older than 75 years old in our investigation. The age of patients was from 75 to 96 years, the average age - 82,6±1,3 years. As for gender, all patients were divided into 2 groups: men - 37 (43,5 %) and female - 48 (56,5 %).

[Association of renal function, telomere length and markers of chronic inflammation for patients without chronic kidney and cardiovascular diseases].

The retrospective analysis of 50 cases of acute myocardial infarction's treatment in patients older than 90 years old was held. Patients' age ranged from 90 to 101 years old. The average age was 92,1±0,7 years.

Optimization of segmental lumbar spine instability treatment using minimally invasive spinal fusion technique.

Unlabelled: Open transforaminal lumbar interbody fusion (TLIF) using transpedicular rods and interbody cage, which is used to treat segmental instability, is associated with a significant paravertebral muscle and ligament injury. A new rigid fusion method was introduced to improve the outcome of patients' treatment.

Objective: To conduct a comparative analysis of the effectiveness of minimally invasive fusion technique and TLIF to improve the treatment results in patients with symptomatic lumbar spine degeneration concomitant with moderate segmental instability of the lumbar spine.

[Ultrasound biomicroscopy findings in the area of previous surgical intervention in refractory glaucoma patients under topical ocular hypotensive therapy].

Aim: to evaluate the effectiveness of different classes of topical hypotensive medications in refractory primary open-angle glaucoma (POAG), judging from structural changes in artificial pathways for intraocular fluid (IOF) visualized with ultrasound biomicroscopy (UBM).

Material And Methods: UBM analysis was performed in 104 eyes of 102 patients, mean age 68.4 ± 0.

[pH values in the pharynx of the patients presenting with compromised nasal breathing of inflammatory and non-inflammatory genesis concomitant with gastroesophageal reflux disease].

The objective of the present study was to estimate the influence of gastroesophageal reflux disease (GERD) on the pH values in the pharynx and nose. It included 87 patients at the age varying from 18 to 81 years admitted to the Irkutsk-based Railway Clinical Hospital and allocated to four groups. Group 1 was comprised of 25 patients presenting with gastroesophageal reflux disease and chronic rhinosinusitis (CRS), group 2 consisted of 29 patients with CRS in the absence of GERD, group 3 included 22 patients with nasal septum deformations (NSD) and GERD, group 4 included 11 patients with NSD and motor rhinitis without GERD.

[Analysis of the state-of-the-art of consulting medical care to patients with glucocorticoid-induced osteoporosis or its risk according to the data of a questionnaire survey (GLUCOST study)].

Aim: To analyze the state-of-the-art of consulting medical care to Russian patients with glucocorticoid-induced osteoporosis (GCOP) or its risk.

Subjects And Methods: This GLUCOST study was organized and conducted by the Russian Association of Osteoporosis. A total of 1129 patients with chronic inflammatory diseases, who had been taking oral glucocorticosteroids (OGCSs) a long time (3 months or more), were examined.

Comparison of EP2006, a filgrastim biosimilar, to the reference: a phase III, randomized, double-blind clinical study in the prevention of severe neutropenia in patients with breast cancer receiving myelosuppressive chemotherapy.

Background: Biosimilars of filgrastim are in widespread clinical use in Europe. This phase III study compares biosimilar filgrastim (EP2006), with the US-licensed reference product, Neupogen(®), in breast cancer patients receiving (neo)adjuvant myelosuppressive chemotherapy (TAC).

Patients And Methods: A total of 218 patients receiving 5 µg/kg/day filgrastim over six chemotherapy cycles were randomized 1:1:1:1 into four arms.

[An experience with neuroprotective therapy of primary open-angle glaucoma based on the use of different dosage forms of Mexidol].

Unlabelled: Aim - to develop an algorithm to guide neuroprotective therapy in railway workers undergoing long-term follow-up for primary open-angle glaucoma (POAG) judging from the efficacy of sequential administration of intravenous dosage form of Mexidol and oral tablets.

Material And Methods: All sorts of JSC Russian Railways employees with stage I-III POAG and well-controlled intraocular pressure were enrolled. Mexidol was first to be administered intravenously by a dropper in a day hospital (250 mg daily for 5 days) and then taken orally at home (125 mg t.

A method for introduction of magnetic nanoparticles into tissues by means of magnetic field gradient: an experimental study.

Targeted effects of magnetic nanoparticles were studied. Solution with iron-containing nanosubstance was applied to resected nasal bone and cartilage tissues. Magnetic field was generated by a Polus-101 device for low-frequency magnetotherapy, which provided permanent work of one inductor (10.

Staging laparoscopy in gastric cancer. Accuracy and impact on therapy.

Background: Surgical therapy remains the most effective treatment modality in gastric cancer. The importance of multimodal treatment for advanced gastric cancer has contributed to the development of more accurate preoperative staging strategies. We examined the diagnostic accuracy of staging laparoscopy (SL) for abdominal metastases and the predictive value of SL for tumor resectability.

Vascular injuries of the limbs: a fifteen-year Georgian experience.

Objectives: to analyse the causes of injury, surgical approaches, outcome and complication of vascular trauma of the upper and lower limbs in patients with vascular injuries operated on over a period between 1981 and 1995.

Patients: in 157 patients, the injuries were penetrating in 136 cases and blunt in 21. Isolated vascular trauma was present in 92 (58.