963 results match your criteria: "Railway Clinical Hospital; University of Medicine and Pharmacy Cluj-Napoca[Affiliation]"

The aim of this retrospective study was to compare corneal parameters and compliance using a Pentacam HR-Scheimpflug (Pentacam HR) and a swept-source OCT Casia (Casia) in keratoconus (KC) patients post penetrating keratoplasty (PKP) and KC patients without PKP, as well as a control group. Pachymetry measurements were also analyzed using a spectral domain OCT Solix (OCT Solix), Pentacam HR, and Casia. The study included 71 patients (136 keratoconic eyes; group A), 86 eyes with KC post-PKP (group B), 50 eyes with KC without PKP (group C), and 52 control participants (104 eyes).

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Sjögren's syndrome (SS) is a slowly progressive, chronic autoimmune inflammatory condition characterized by the affliction of the exocrine glands, with issues that derive from it markedly decreasing the quality of life of these patients. Salivary gland involvement can be identified through imaging methods. Among them, salivary gland ultrasonography (SGUS) is used as a diagnostic and prognostic tool in pSS.

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Cutaneous malignant melanoma (MM) is the most aggressive form of skin cancer, associated with high mortality and rising incidence rates in Europe despite prevention efforts. Nodular MM, the most aggressive subtype, often mimics other skin tumors, complicating diagnosis. We present the case of a 66-year-old woman with a large, ulcerated tumor beneath the left scapula, along with multiple nodular lesions on the left arm and chest.

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Background & objectives Biobanks are crucial for biomedical research, enabling new treatments and medical advancements. The biobank at the Madras Diabetes Research Foundation (MDRF) aims to gather, process, store, and distribute biospecimens to assist scientific studies. Methods This article details the profile of two cohorts: the Indian Council of Medical Research-India Diabetes (ICMR-INDIAB) study and the Registry of people with diabetes in India with young age at onset (ICMR-YDR).

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A 70-year-old woman was admitted to our hospital with dyspnea. Atypical cells with multilobated nuclei were observed in the pleural effusion. Diffuse large B-cell lymphoma (DLBCL) was diagnosed based on a cell block analysis.

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Risk factors for postoperative recurrence after full-endoscopic microvascular decompression for trigeminal neuralgia: a retrospective study and predictive nomogram.

Eur J Med Res

December 2024

Department of Neurosurgery, Neuromedicine Center, Beijing Shijitan Hospital, Capital Medical University, No. 10, Tieyi Road, Yangfangdian, Haidian District, Beijing, 100038, People's Republic of China.

Background: Full-endoscopic microvascular decompression (fE-MVD) is an emerging treatment option for trigeminal neuralgia (TN). However, the risk factors associated with postoperative recurrence of TN after fE-MVD procedure remain controversial. The aim of the present study was to summarize the surgical technique of fE-MVD for the treatment of TN and to develop a predictive model for recurrence at 1 year postoperatively based on independent risk factors.

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Background Context: The effect of romosozumab administration in patients undergoing corrective spinal fusion surgery has not yet been analyzed.

Purpose: To examine the effect of romosozumab administration on reducing the incidence of proximal junctional kyphosis (PJK), particularly PJK due to fractures (PJK-Fx), in patients undergoing spinal corrective fusion surgery.

Design: Retrospective cohort study.

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Unlabelled: The aim of this work is to study the mechanical properties of temporary composite crowns and temporary composite orthopedic structures manufactured by 3D printing.

Materials And Methods: For the two studied groups of samples: the original 3D-printed samples and the poured samples from a composite material of a certain shape, 8 samples were made and visually checked for the absence of porosity. The strength and elasticity were measured using the three-point bending method and the hardness was measured using the indentation method.

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Predictive value of placental growth factor level for adverse pregnancy outcome in twin pregnancies at advanced maternal age.

Am J Transl Res

November 2024

Department of Gynaecology and Obstetrics, General Global China Railway Xi'an Hospital No. 319, East Section of South Second Ring Road, Beilin District, Xi'an 710000, Shaanxi, China.

Objective: To investigate the predictive value of placental growth factor (PlGF) for adverse pregnancy outcome in twin pregnancies at advanced maternal age.

Methods: A retrospective analysis was conducted on 387 women with twin pregnancies who delivered at Northwest Women's and Children's Hospital between March 2020 and March 2024. The women were divided into a favorable outcome group (n = 249) and an adverse outcome group (n = 138) based on their pregnancy outcome.

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Home blood pressure (HBP) monitoring is a better prognostic predictor than clinical BP monitoring. However, the suggested number of HBP measurements in each occasion varies across guidelines. The study aimed to identify which HBP measurements in each occasion are more closely associated with new cardiovascular events in patients with type 2 diabetes.

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Article Synopsis
  • The study assessed the effectiveness of serum type 4 collagen 7S (COL4-7S) compared to the Enhanced Liver Fibrosis (ELF) score in detecting liver fibrosis in patients with metabolic dysfunction-associated steatotic liver disease (MASLD).
  • Among 1,368 patients, 794 were analyzed, revealing that both COL4-7S and ELF scores rise with increasing fibrosis, but COL4-7S showed significantly better performance for identifying advanced fibrosis (≥2) especially in diabetic patients.
  • Overall, COL4-7S proved to be at least as effective as the ELF score in diagnosing advanced liver disease in MASLD patients.
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Unlabelled: To date, the optimal therapeutic and diagnostic strategy in patients with simultaneous clinical manifestations of degenerative cervical spine disease and upper-extremity nerve compression is still unclear.

Objective: To analyze the results of simultaneous surgical interventions in patients with cervical radiculopathy combined with distal peripheral compression-induced ischemic neuropathy.

Material And Methods: We retrospectively studied postoperative outcomes in 23 patients with two-level degenerative cervical spine disease with radiculopathy and peripheral nerve compression (cubital canal, Guyon's canal or carpal tunnel syndromes).

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Application of dynamic navigation technology in oral and maxillofacial surgery.

Clin Oral Investig

December 2024

State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, 237 Luoyu Road, Wuhan, Hubei, 430079, China.

Objectives: Dynamic navigation (DN) technology has ushered in a paradigm shift in dentistry, revolutionizing the precision of diverse procedures in oral and craniofacial surgery. This comprehensive review aims to review the manifold applications of DN, including implantology, endodontics, oral and dental surgeries, and other dental disciplines.

Materials And Methods: A thorough search of the online databases PubMed and Google Scholar was conducted up to March 2024.

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Preventing subsequent fractures after vertebral augmentation is a critical clinical concern. The purpose of this study was to compare the effect of romosozumab and bisphosphonate administration on the occurrence of subsequent vertebral fractures after balloon kyphoplasty (BKP) and to identify factors associated with the occurrence of subsequent vertebral fractures. The study compared 24 patients who underwent BKP and received romosozumab with 58 control patients who underwent BKP and received bisphosphonates, all within 2 months of acute osteoporotic vertebral fracture and showing unfavorable magnetic resonance imaging prognostic factors.

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Background: Ulnar shortening osteotomy (USO) is a well-established surgical technique for ulnar impaction syndrome and triangular fibrocartilage complex injuries, but complications like delayed union and nonunion are often encountered. Transverse and oblique osteotomy techniques are commonly used, yet direct comparisons using advanced implants are limited. This study aims to compare the clinical and radiological outcomes of USO using the Jplate with a transverse osteotomy device and the APTUS Wrist Ulna Shortening System 2.

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A New Neuroanesthetic Protocol of Rendering Specialized Care in Treating Degenerative Lumbar Spine Diseases in High-Risk Patients: Prospective Analysis of the Results.

Sovrem Tekhnologii Med

December 2024

MD, DSc, Professor, Head of the Department of Neurosurgery and Innovative Medicine; Irkutsk State Medical University, 1 Krasnogo Vosstaniya St., Irkutsk, 664003, Russia; Chief of the Center of Neurosurgery; Russian Railways-Medicine Clinical Hospital, 10 Botkin St., Irkutsk, 664005, Russia; Professor, Department of Traumatology, Orthopedics and Neurosurgery; Irkutsk State Medical Academy of Postgraduate Education, 100 Yubileyny Microdistrict, Irkutsk, 664049, Russia.

Unlabelled: is to assess the effectiveness of a new neuroanesthetic protocol for treating degenerative lumbar spine diseases in high-risk patients.

Materials And Methods: Two groups of patients with a high risk of anesthesia and surgery determined by the authors' clinical decision support system (CDSS) have been prospectively studied. A new neuroanesthetic protocol was used in the experimental group (EG, n=25), while the control group (CG, n=25) underwent intravenous anesthesia based on propofol and fentanyl.

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Article Synopsis
  • - The study aimed to evaluate the effectiveness of muscle energy technique (MET) combined with conventional physical therapy for patients with knee osteoarthritis (OA) who underwent mesenchymal stem cell transplantation, comparing it to conventional therapy alone.
  • - Conducted over 11 months, the trial involved two treatment groups receiving three weekly sessions, assessing pain and function through various scales, with significant statistical analysis used to determine results.
  • - Findings indicated that while both treatment approaches improved knee pain and function, the MET combined with conventional therapy resulted in more significant improvements in knee pain, range of motion, and functional limitations.
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Diagnostic efficacy of combined high- and low-frequency ultrasound in post-hematopoietic stem cell transplantation ureteral obstruction in leukemia patients.

Int Urol Nephrol

November 2024

The Department of Ultrasonic, Yanjiao Development Zone, Yanda Ludaopei Hospital, Yanda International Health City, West of Sipulan Road and South of Beijing-Qin Railway, Sanhe City, Langfang City, Hebei Province, China.

Purpose: The objective of this study was to evaluate the diagnostic efficacy of high- and low-frequency ultrasound (H&LFUS) in the imaging of post-hematopoietic stem cell transplantation (post-HSCT) ureteral obstruction in leukemia patients.

Methods: A total of 103 patients who received HSCT for leukemia were included in this retrospective study. Patients underwent examinations using high-frequency ultrasound (HFUS), low-frequency ultrasound (LFUS), and the combined use of H&LFUS approach.

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The purpose of this study is to evaluate clinical outcomes and early postoperative complications in patients undergoing Boston type I keratoprosthesis (BKPro) implantation, with a specific focus on the onset and nature of ocular surface disorders during the early postoperative period. This retrospective study included 77 eyes that underwent BKPro implantation between 2019 and March 2022. Patients were treated at the Saint Barbara Hospital, Trauma Centre, Sosnowiec, Poland, and District Railway Hospital, Katowice, Poland.

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Background: With the rising prevalence of abdominal radical hysterectomy, the need for perioperative blood transfusion has emerged as a significant clinical challenge. Independent risk factors for blood transfusion during abdominal radical hysterectomy remains limited, and identifying these factors is needed.

Methods: A retrospective analysis of data was performed using the Nationwide Inpatient Sample (NIS), focusing on patients who underwent abdominal radical hysterectomy between 2010 and 2019.

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Development of a novel multiplex digital PCR-based method for the detection of HTLV-1 proviral deletion.

J Virol Methods

February 2025

Research Center for Biological Products in the Next Generation, National Institute of Infectious Diseases, Tokyo, Japan. Electronic address:

The human T-cell leukemia virus type 1 (HTLV-1), a retrovirus, integrates into host DNA and causes adult T-cell leukemia/lymphoma (ATL) in some individuals. Two types of defective proviruses, Type 1 and Type 2, are often observed in ATL cells. Here, we developed a 3-plex digital PCR (dPCR) method to detect HTLV-1 proviral deletions by comparing the ratios of copy numbers quantified using specific primer-probes for the LTR, pol, and pX regions.

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Introduction: Erectile dysfunction is often a consequence of stressful situations, lack of adequate sleep and rest, and sedentary lifestyles. The profession of locomotive engineer implies the presence of these negative factors, which in addition provoke high blood pressure and the development of hypertension.

Materials And Methods: A total of 85 patients of the urological and therapeutic departments of the "Clinical Hospital "Russian Railways Medicine" in the city of Barnaul", working as locomotive drivers or assistant drivers, were examined.

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Mannitol for bowel preparation: Efficacy and safety results from the SATISFACTION randomised clinical trial.

Dig Liver Dis

November 2024

Praxis für Gastroenterologie und Fachärztliche Innere Medizin, Im Haus der Gesundheit, Ludwigshafen am Rhein, Germany.

Background: Bowel preparation represents a significant issue to high-quality colonoscopy. Oral mannitol requires a single dose, is of low volume, and has a pleasant taste and rapid action.

Aims: This SATISFACTION study compared single-dose (same day) oral mannitol 100 g/750 mL with standard split-dose PEG-ASC2 L (MoviPrep®).

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The Triple Procedure in Patients with Congenital Aniridia.

J Clin Med

November 2024

Chair and Clinical Department of Ophthalmology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, 65 Panewnicka Street, 40-760 Katowice, Poland.

Aniridia is a rare panocular, bilateral, and congenital disease characterized by complete or partial iris hypoplasia and foveal hypoplasia, leading to decreased visual acuity and nystagmus. AAK, also referred to as aniridic keratopathy, manifests as corneal surface damage, epithelial thinning or loss, inflammation with immune cell infiltration, vascularization, and chronic progressive opacification. Twenty-one eyes in eighteen patients with aniridia underwent the triple procedure for visual rehabilitation.

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Thank you for your thoughtful and insightful commentary on our paper, "Outcomes of Boston Keratoprosthesis Type I Implantation in Poland: A Retrospective Study on 118 Patients" [...

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