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Affect and neural activity in women with PTSD during a task of emotional interference.

J Affect Disord

November 2016

Departments of Psychiatry, Radiology, and Neurology, Washington University, St. Louis, MO, USA; Departments of Psychiatry, Radiology and Neurology University of Pennsylvania, Philadelphia, PA, USA.

Background: The current study sought to determine the relationship between self-reported dimensions of affect and activation in brain regions associated with emotion regulation in PTSD during a task of non-conscious emotional processing in interpersonal trauma survivors with PTSD and healthy controls.

Methods: Participants included 52 women diagnosed with PTSD and 18 female healthy controls. All participants completed a clinical assessment including the SCID, CAPS, and PANAS followed by a functional MRI assessment including a task of implicit emotional conflict.

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