74 results match your criteria: "Radiation-Induced Brachial Plexopathy"
Cureus
November 2024
Department of Radiation Oncology, Nuvance Health, Norwalk, USA.
Int J Surg Case Rep
November 2024
Department of Rehabilitation, King Hussein Cancer Center, Amman, Jordan.
J Hand Surg Am
November 2024
Department of Orthopedic Surgery, Division of Hand and Microsurgery; Washington University School of Medicine, St. Louis, MO. Electronic address:
Cureus
September 2024
Pain Medicine, Singapore General Hospital, Singapore, SGP.
Physiother Theory Pract
September 2024
Occupational Therapist, St. Paul's Hospital, Providence Health Care, Vancouver, British Columbia, Canada.
Rep Pract Oncol Radiother
July 2024
Biostatistics, St John's Medical College Hospital, Bangalore, India.
Background: Definitive concurrent chemoradiotherapy (CRT) is the standard of care in advanced stages of head and neck cancer (HNC). With evident increase in survival rate there is also simultaneous increase in toxicity affecting the quality of life. One of the less researched late toxicity is radiation induced brachial plexopathy (RIBP).
View Article and Find Full Text PDFCureus
May 2024
Radiology, Datta Meghe Institute of Higher Education & Research, Wardha, IND.
Front Oncol
April 2024
Division of Radiation Oncology, Department of Radiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Cureus
January 2024
Radiation Therapeutics and Oncology, Tokyo Medical and Dental University, Tokyo, JPN.
This case report details a rare instance of radiation-induced brachial plexopathy (RIBP) occurring below the typical tolerance dose in a 55-year-old woman following chemoradiotherapy for apical non-small cell lung carcinoma. Despite receiving a radiation dose considered safe (47-48 Gray in 25 fractions), she developed sensory abnormalities and motor weakness in the right upper limb. The diagnostic distinction between RIBP and tumor recurrence was achieved using MRI, which showed characteristic features of radiation-induced damage.
View Article and Find Full Text PDFRadiother Oncol
January 2024
Department of Radiation Oncology, CyberKnife Center, and Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute & Hospital, Tianjin's Clinical Research Center for Cancer, National Clinical Research Center for Cancer, Tianjin, China. Electronic address:
Hand (N Y)
November 2024
Division of Hand & Peripheral Nerve Surgery, Department of Orthopedic Surgery, Mayo Clinic, Phoenix, AZ, USA.
Radiation-induced brachial plexopathy (RIBP) is a rare long-term complication of radiation therapy often causing pain, motor deficit, and overall quality of life reduction for affected patients. While a standard treatment for RIBP is yet to be established, management consists mostly of symptom management through the use of medications and physical therapy. There is a lack of evidence regarding the efficacy of surgical treatment.
View Article and Find Full Text PDFJ Hand Surg Eur Vol
April 2024
Division of Plastic & Reconstructive Surgery, Department of Surgery, University of Florida, Gainesville, FL, USA.
This systematic literature review of the clinical characteristics of radiation-induced brachial plexopathy and outcomes after intervention includes 30 trials with 611 patients. The mean radiation dose to the brachial plexus was 56 Gy, and the mean duration of radiation was 4 weeks. The mean time from radiation to the onset of symptoms was 35 months.
View Article and Find Full Text PDFPM R
January 2024
Department of Physical Therapy - Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Radiother Oncol
May 2023
Department of Radiation Oncology, ThedaCare Regional Medical Center, Appleton, WI, USA.
Introduction: Radiation-induced brachial plexopathy (RIBP), resulting in symptomatic motor or sensory deficits of the upper extremity, is a risk after exposure of the brachial plexus to therapeutic doses of radiation. We sought to model dosimetric factors associated with risks of RIBP after stereotactic body radiotherapy (SBRT).
Methods: From a prior systematic review, 4 studies were identified that included individual patient data amenable to normal tissue complication probability (NTCP) modelling after SBRT for apical lung tumors.
Int J Radiat Oncol Biol Phys
March 2024
Department of Radiation Oncology and Lineberger Cancer Center, University of North Carolina, Chapel Hill, North Carolina.
We sought to systematically review and summarize dosimetric factors associated with radiation-induced brachial plexopathy (RIBP) after stereotactic body radiation therapy (SBRT) or hypofractionated image guided radiation therapy (HIGRT). From published studies identified from searches of PubMed and Embase databases, data quantifying risks of RIBP after 1- to 10-fraction SBRT/HIGRT were extracted and summarized. Published studies have reported <10% risks of RIBP with maximum doses (D) to the inferior aspect of the brachial plexus of 32 Gy in 5 fractions and 25 Gy in 3 fractions.
View Article and Find Full Text PDFOper Neurosurg (Hagerstown)
January 2023
Department of Hand Surgery, Beijing Ji Shui Tan Hospital, Beijing, China.
Background: There is no consensus on the optimal treatment for radiation-induced brachial plexopathy (RIBP).
Objective: To present our experience of using nerve resection and autografting as a treatment strategy for this challenging condition.
Methods: From September 2014 to January 2020, 8 patients with RIBP were treated with segmental nerve resection and autografting, with or without other supplementary procedures.
Cancer Radiother
April 2023
Centre de radiothérapie Marie-Curie, Valence, France. Electronic address:
Neurology
February 2022
From the Department of Neurology (M.T.J.P., N.A.S., M.P.G.B.), Maastricht University Medical Center; and GROW-School for Oncology and Developmental Biology (M.P.G.B.), Maastricht University, the Netherlands.
BMJ Case Rep
September 2021
Department of Neurology, Mater Dei Hospital, Msida, Malta.
The late-onset variant of radiation-induced brachial plexopathy is most often seen after treatment for breast or lung cancers. It has an insidious onset, with symptoms noted years after receiving radiotherapy, and the condition gradually continues to deteriorate with time. We present the case of an elderly man who we saw in view of worsening paraesthesias and weakness of his left arm with associated prominent muscle wasting along the left shoulder girdle.
View Article and Find Full Text PDFPract Radiat Oncol
September 2021
University of Wisconsin School of Medicine and Public Health, Department of Human Oncology, Madison, Wisconsin.
Adv Radiat Oncol
October 2020
Department of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri.
Purpose: Our purpose was to describe the risk of radiation-induced brachial plexopathy (RIBP) in patients with breast cancer who received comprehensive adjuvant radiation therapy (RT).
Methods And Materials: Records for 498 patients who received comprehensive adjuvant RT (treatment of any residual breast tissue, the underlying chest wall, and regional nodes) between 2004 and 2012 were retrospectively reviewed. All patients were treated with conventional 3 to 5 field technique (CRT) until 2008, after which intensity modulated RT (IMRT) was introduced.
Autops Case Rep
September 2020
Universidade de São Paulo (USP), Faculdade de Medicina, Hospital das Clínicas, Instituto de Psiquiatria, Peripheral Nerves Group, São Paulo, SP, Brasil.
Radiation-induced brachial plexus neuropathy (RIBPN) is a rare and delayed non-traumatic injury to the brachial plexus, which occurs following radiation therapy to the chest wall, neck, and/or axilla in previously treated patients with cancer. The incidence of RIBPN is more common in patients treated for carcinoma of the breast and Hodgkin lymphoma. With the improvement in radiation techniques, the incidence of injury to the brachial plexus following radiotherapy has dramatically reduced.
View Article and Find Full Text PDFPain Med
March 2021
Department of Anesthesiology and Perioperative Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Radiation therapy is used as a form of treatment for various neoplastic diseases. There are many potential adverse effects of this therapy, including radiation-induced neurotoxicity. Radiation-induced brachial plexopathy (RIBP) may occur due to the fibrosis of neural and perineural soft tissues, leading to ischemic damage of the axons and Schwann cells.
View Article and Find Full Text PDFNeurology
March 2021
From the Department of Neurology, Yokohama City Minato Red Cross Hospital, Japan.
Breast J
October 2020
Department of Medical Oncology, Cork University Hospital, Co Cork, Ireland.