17,875 results match your criteria: "Radiation Necrosis"
Eur J Surg Oncol
January 2025
Department of Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea. Electronic address:
Sci Rep
November 2024
Department of Radiation Oncology, Miami Cancer Institute, Baptist Health South Florida, 8900 N Kendall Drive, Miami, FL, 33176, USA.
Neurosurg Focus
November 2024
1Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California; and.
Neurosurg Focus
November 2024
Departments of2Neurological Surgery and.
Objective: Radiation necrosis is becoming an increasingly prevalent complication in patients with brain tumors given the growing utility of stereotactic radiosurgery in modern treatment paradigms. Magnetic resonance-guided laser interstitial thermal therapy (MRgLITT) is a new minimally invasive modality that has exhibited an efficacy comparable to craniotomy in treating radiation necrosis. No studies to date have compared their cost-effectiveness despite the significant additional expenses associated with MRgLITT use.
View Article and Find Full Text PDFJ Neurosurg
November 2024
Departments of1Radiation Oncology and.
Lasers Med Sci
November 2024
Departamento de Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Juiz de Fora, Rua José Lourenço Khelmer - s/n, Campus Universitário, São Pedro, Juiz de Fora, Minas Gerais, 36036900, Brazil.
Photodynamic therapy (PDT) is an alternative to cancer treatment, demonstrating selectivity and significant cytotoxicity on malignant tissues. Such therapy involves two nontoxic components: photosensitizer (PS) and non-ionizing radiation. In optimal dosage combinations, PDT causes cellular and tissue effects by oxygen-dependent processes, leading tumor cells to regulated cell death pathways.
View Article and Find Full Text PDFPract Radiat Oncol
October 2024
Department of Oncology, Division of Radiation Oncology, McGill University Hospital Centre. Electronic address:
Background And Purpose: We aimed to determine if ultra-hypofractionated radiotherapy (UHYPO-RT) delivering 6Gy x 5 fractions yields similar tumour necrosis compared to conventional radiotherapy (CONV-RT) with 2Gy x 25 fractions in soft tissue sarcoma (STS). The clinical significance of tumor necrosis on loco-regional recurrence-free survival (LRFS), distant disease-free survival (DDFS), and overall survival (OS) were assessed.
Materials And Methods: Patients with localised STS treated with CONV-RT or UHYPO-RT followed by surgery were included.
Cureus
September 2024
Department of Respiratory Medicine, National Hospital Organization (NHO) Nagasaki Medical Center, Nagasaki, JPN.
It is well known that bevacizumab is effective against radiation necrosis in the brain (hereafter referred to as brain necrosis). Herein, we report a case of brain necrosis in a patient treated with a regimen that included ramucirumab, an anti-vascular endothelial growth factor (VEGF) inhibitor. A woman in her 40s presented with five brain metastases from lung adenocarcinoma at the initial diagnosis.
View Article and Find Full Text PDFStem Cells Int
October 2024
School of Medicine, Nankai University, Tianjin 300071, China.
Dental trauma is highly prevalent in children and adolescents, alongside tooth decay. This condition mainly induces pulp contamination, pulp necrosis, and tooth avulsion in the clinical context. The disturbance to root growth is prone to occur in immature permanent teeth.
View Article and Find Full Text PDFBr J Hosp Med (Lond)
October 2024
Department of Radiology, Ankara University Medical School, Ankara, Turkey.
Lesions with central hypointensity and peripheral contrast enhancement are defined as ring-enhancing lesions. The aetiologies of ring-enhancing lesions may be various, including infections, tumours, demyelinating diseases, treatment-related conditions and hematoma. The imaging findings and their distinguishing features also vary among different ring-enhancing lesions.
View Article and Find Full Text PDFRadiat Oncol
October 2024
Department of Radiation Oncology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China.
Oral Surg Oral Med Oral Pathol Oral Radiol
January 2025
Department of Oral and Maxillofacial Surgery and Facial Plastic Surgery, University Hospital, LMU Munich, Germany.
Biomaterials
April 2025
Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Donghu Avenue No.185, Wuhan, 430072, China; Hubei Provincial Key Laboratory of Developmentally Originated Disease, Wuhan, 430072, China. Electronic address:
In this study, we demonstrated the mechanism of a glioblastoma (GBM)-targeted sonodynamic therapy (SDT) strategy employing platelets loaded with a sonosensitizer based on functionalized boron nitride nanoparticles carrying chlorin e6 (BNPD-Ce6). In the in vitro study, we first found that the BNPD-Ce6-mediated sonodynamic action (SDA) induced remarkable viability loss, DNA damage, and cell death in the GBM cells (GBCs) but not macrophages. Surprisingly, the SDA-exposed GBCs displayed a ferroptotic phenotype while the SDA-exposed macrophages underwent immuno-stimulatory autophagy and potently potentiated the SDA's toxicity to the GBCs.
View Article and Find Full Text PDFPlant Biol (Stuttg)
January 2025
Smithsonian Tropical Research Institute, Panama City, Republic of Panama.
Tropical rainforests are hot and may be particularly sensitive to ongoing anthropogenic global warming. This has led to increased interest in the thermotolerance of tropical trees. Thermotolerance of leaves of two tropical tree species, Terminalia catappa and Coccoloba uvifera, was determined by exposing leaf samples to 15-min heat treatments, followed by measurements of potential photosystem II quantum yield (dark-adapted value of variable/maximum chlorophyll a fluorescence, F/F) after 24 h and 14 days, and visible damage (necrosis) after 14 days.
View Article and Find Full Text PDFInt J Mol Sci
October 2024
New York Proton Center, New York, NY 10035, USA.
Cancers (Basel)
October 2024
Department of Radiation Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
Background/objectives: To determine the impact of stereotactic radiosurgery on outcomes of metastatic breast cancer with intracranial metastases.
Methods: We systematically searched the PubMed and EMBASE databases for studies published between 1 January 1990 and 1 August 2024. Primary research articles evaluating the outcomes of stereotactic radiosurgery on intracranial metastases from breast cancer were included.
Biomolecules
October 2024
Department of Anesthesiology, Faculty of Medicine, University Hospital, Heinrich-Heine-University, 40225 Düsseldorf, Germany.
Human monocytes can be subdivided into phenotypically and functionally different classical, intermediate and non-classical monocytes according to the cell surface expression of CD14 and CD16. A precise identification and characterisation of monocyte subsets is necessary to unravel their role in inflammatory diseases. Here, we compared three different flow cytometric strategies (A-C) and found that strategy C, which included staining against CD11b, HLA-DR, CD14 and CD16, followed by several gating steps, most reliably identified monocyte subtypes in blood samples from healthy volunteers and from patients with stable coronary heart disease (CHD) or ST-elevation myocardial infarction (STEMI).
View Article and Find Full Text PDFTumori
December 2024
Department of Radiation Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.
Purpose: This study aimed to compare the incidence of fat necrosis after accelerated partial breast irradiation (APBI) vs hypofractionated whole breast irradiation (WBI) in patients with early-stage breast cancer.
Materials And Methods: Data from early-stage breast cancer patients who underwent breast-conserving surgery and adjuvant radiotherapy between 2009 and 2022 were retrospectively collected. Radiation therapy consisted of APBI of 30 Gy in 5 daily fractions (Fx) (delivered in one week, consecutively) to the tumour bed or WBI (42.
J Med Chem
November 2024
Faculty of Chemistry, Jagiellonian University, Gronostajowa 2, 30-387 Cracow, Poland.
A photoactive analogue of cisplatin was synthesized with two arylazopyrazole ligands, able to undergo -/- photoisomerizations. The photoisomer showed a dark half-life of 9 days. The cytotoxicities of both photoisomers of the complex were determined in several cancer and normal cell lines and compared to that of cisplatin.
View Article and Find Full Text PDFPlast Reconstr Surg Glob Open
October 2024
From the Plastic Surgery Department, Hotel Dieu de France University Hospital, Saint Joseph University, Beirut, Lebanon.
Int J Biol Macromol
December 2024
School of Chinese Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China. Electronic address:
Lavandula angustifolia Mill. is a traditional Chinese medicinal herb with high economic and pharmacological value. In this study, we optimized the conditions for low-temperature ultrasound-assisted extraction of L.
View Article and Find Full Text PDFJ Magn Reson Imaging
October 2024
Department of Radiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Guangxi Academy of Medical Sciences, Nanning, Guangxi, China.
J Cancer
September 2024
University of Hawai'i Cancer Center, 701 Ilalo Street Honolulu, HI 96813, USA.
Cancer-associated macrophage-like cells (CAMLs) are rare, gigantic, and atypical circulating cells found exclusively in the peripheral blood of patients with solid cancers. Obesity-induced hypoxia attracts macrophages to the tumor microenvironment, where they contribute to establishing chronic inflammation, leading to cancer progression. We hypothesized that obese patients with advanced breast cancer may have CAML profiles different from those of nonobese patients, and these profiles may correlate with proinflammatory markers or other macrophage-related markers.
View Article and Find Full Text PDFEcotoxicol Environ Saf
November 2024
Key Laboratory of Occupational Environment and Health, Guangzhou Occupational Disease Prevention and Treatment Hospital, Guangzhou, China; Institute of Occupational and Environmental Health, Guangzhou Medical University, Guangzhou, China. Electronic address:
Adv Radiat Oncol
November 2024
Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.