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Risk factors for non-sentinel lymph node metastases in patients with breast cancer. The outcome of a multi-institutional study.
Ann Surg Oncol
January 2007
Department of Surgery, Radboud University Nijmegen Medical Center (MC), Nijmegen, The Netherlands.
Background: In this multi-institutional prospective study, we evaluated whether we could identify risk factors predictive for non-sentinel lymph node (non-SN) metastases in breast cancer patients with a positive sentinel lymph node (SN).
Methods: In this multi-institutional study, 541 eligible breast cancer patients were included prospectively.
Results: The occurrence of non-SN metastases was related to the size of the SN metastasis (P = .