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Physical activity is related to the structural integrity of cerebral white matter.
Neurology
September 2013
From the Department of Neurology (R.A.R.G.), Catharina Hospital, Eindhoven; Donders Institute for Brain, Cognition and Behavior, Center for Neuroscience, Departments of Neurology (R.A.R.G., A.M.T., K.F.d. L., A.G.W.v.N., E.J.v.D., F.-E.d.L.) and Psychiatry (M.P.Z.), Radboud University Nijmegen Medical Center; and Donders Institute for Brain, Cognition and Behavior, Center for Cognitive Neuroimaging, Radboud University Nijmegen (D.G.N., M.P.Z.), the Netherlands.
Objective: To investigate the relation between physical exercise and the microstructural integrity of cerebral white matter.
Methods: Four hundred forty individuals with cerebral small-vessel disease, aged between 50 and 85 years, without dementia, were included and underwent MRI scanning. Physical exercise was assessed with a structured questionnaire.