2 results match your criteria: "Rabat Institute University Mohamed V[Affiliation]"

Availability of antidotes in Moroccan hospitals: a national survey.

Eur J Hosp Pharm

May 2023

Pharmacology and Toxicology Department, Faculty of Medicine and Pharmacy, Rabat Institute University Mohamed V, Rabat, Morocco.

Aim: The lack of availability of antidotes is a challenge for hospitals all over the world. The objective of our study was to investigate the availability of antidotes in Moroccan hospitals.

Methods: A cross-sectional, questionnaire-based study was conducted from November 2018 to April 2019.

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Background: Despite many studies suggesting an association between human leukocyte antigen (HLA)-B*15:02 and carbamazepine (CBZ)-induced severe cutaneous adverse drug reactions essentially toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS), the evidence of association in different populations and the degree of association remain uncertain.

Materials And Methods: The primary analysis was based on population control studies. Data were pooled by means of a random-effects model, and sensitivity, specificity, positive and negative likelihood ratios (LR+ and LR-), diagnostic odds ratios (DOR), and areas under the summary receiver operating characteristic curve (AUC) were calculated.

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