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An Inpatient Protocol for the Treatment of Methamphetamine Withdrawal in Patients With and Without Opioid Use Disorder.

J Addict Med

March 2024

From the Department of Psychiatry, Massachusetts General Hospital, Boston, MA (TEW, RLHW); Harvard Medical School, Boston, MA (TEW); Bay Cove Human Services, Boston, MA (LB, AT, JO).

Objective: Increasing rates of methamphetamine (METH) use, use disorders, and related overdoses are a growing public health problem. There are a lack of protocols addressing METH intoxication and withdrawal symptoms that manifest during acute withdrawal treatment resulting in inpatient management difficulties and premature discharges. This report presents a novel treatment protocol comprised of behavior-targeted and pharmacological components that aims to reduce the intensity and duration of METH intoxication and withdrawal related symptoms during early treatment, improve retention, and provide clinicians with a tool to meet this growing problem.

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