Rickets Secondary to Distal Renal Tubular Acidosis: A Rare Etiology With a Five-Year Follow-Up of Clinical and Radiological Outcomes and Literature Review.

Distal renal tubular acidosis (dRTA) is one of the rare causes of rickets in children. In this case report, we describe a 13-year-old male patient who presented with short stature, bilateral genu valgum, and a history of recurrent weakness in the lower limbs. Radiological observations were consistent with rickets with bony deformities.

Principles and Therapeutics of .

Health is defined as a state of complete physical, mental, and social wellbeing, not merely the absence of diseases or infirmity. means selfless sacrifices performed along with sacred sounds, the mantras. The procedure includes offering selected herbal and sacred materials to the fire to obtain an array of benefits such as air purification and release of therapeutic compounds (antibacterial, antiviral, antifungal, antidepression, and anticonvulsant) in the form of aerosol that enriches the atmosphere and soil.

Personalized immunization against Mpox Clades I and Ib: Strategies to combat the emerging epidemic.

Mpox, formerly known as monkeypox, is a zoonotic virus of the genus, with recent outbreaks of Clade I and Ib in Central Africa presenting a considerable global health threat. This study reviews current Mpox immunization approaches, focusing on the MVA-BN, LC16-KMB, and OrthopoxVac vaccines. MVA-BN vaccination has been successful in lowering infection risks, particularly in high-risk individuals and is widely used in the USA.

Accuracy of artificial intelligence-based segmentation in maxillofacial structures: a systematic review.

Objective: The aim of this review was to evaluate the accuracy of artificial intelligence (AI) in the segmentation of teeth, jawbone (maxilla, mandible with temporomandibular joint), and mandibular (inferior alveolar) canal in CBCT and CT scans.

Materials And Methods: Articles were retrieved from MEDLINE, Cochrane CENTRAL, IEEE Xplore, and Google Scholar. Eligible studies were analyzed thematically, and their quality was appraised using the JBI checklist for diagnostic test accuracy studies.

Assessing Autonomic Dysfunction in Diabetes: A Hospital-based Study in a Developing Country.

Background: Autonomic nervous system (ANS) dysfunction is a common complication in patients with diabetes mellitus, potentially affecting the various organ systems leading to significant morbidity. This study aimed to evaluate ANS dysfunction in diabetic patients attending Wad Madani Teaching Hospital, Sudan.

Materials And Methods: A cross-sectional and hospital-based study was conducted on a sample of 100 patients in Wad Madani Teaching Hospital in Sudan.

Uncommon Handlebar Hernia in an Adult Treated With Laparoscopy and Open Anatomical Repair.

Handlebar hernias, a form of traumatic abdominal wall hernia, are rare injuries resulting from blunt abdominal trauma in adults. Robust suspicion is essential for diagnosis given the subtle symptoms and intact skin. A 48-year-old male arrived with pain and swelling on the left side of his abdomen after a low-speed bicycle crash.

A Randomized Controlled Trial Evaluating the Effect of Local Application of Sodium Alendronate Gel and Low-Level Laser Therapy (LLLT) On Peri-Implant Tissue Healing in Wistar Rats.

Objective: To evaluate the effect of local application of Sodium Alendronate incorporated in Carbapol gel together with LLLT on peri-implant tissue healing in Wistar rat femurs.

Methods: Twenty-four male Wistar rats were randomly divided into 4 groups: Group 1 (the control group), Group 2 (the Sodium Alendronate group), Group 3 (the Sodium Alendronate and LLLT group), and Group 4 (the LLLT group). Mini implants were placed in right and left femur bones in all the four groups.

Eastern equine encephalitis virus: Pathogenesis, immune response, and clinical manifestations.

Eastern equine encephalitis virus (EEEV) is a lethal transmitted by mosquitoes that primarily cycles between birds. Although rare, infections in humans and horses are associated with high mortality rates and severe neurological effects. Climate change appears to be increasing the spread of this virus.

Preferences for thromboprophylaxis in the intensive care unit: An international survey.

Background: Venous thromboembolism (VTE) is a frequent complication in critically ill patients, who often have multiple risk factors. Pharmacological thromboprophylaxis is widely applied to lower this risk, but guidelines lack dosing recommendations.

Objective: This survey aims to assess current thromboprophylaxis preferences and willingness to participate in future randomized clinical trials (RCTs) on this topic.

Moderating Effect of Interpersonal Mindfulness Between Marital Conflict and Marital Intimacy Among Iranian Married Individuals.

Purpose: Marital intimacy is one of the significant factors determining life quality, which, along with interpersonal mindfulness, enables married individuals to experience greater levels of marital satisfaction. This study aimed to elucidate and confirm the moderating effects of interpersonal mindfulness in the relationship between marital conflict and marital intimacy.

Method: The participants of this study comprised 207 Iranian married individuals (ages 19 to 45 years, mean age: 30, SD: ±4.

Virtual perspectives of sanguinarine on cancer prevention and treatment through molecular dynamic study.

Cancer prevention involves resisting cancer development at initial stages, retarding angiogenesis and initiating cancer cell apoptosis. Through the use of virtual screening, binding free energy calculations, and molecular dynamics simulations, we were able to identify compounds with potential anticancer activity."During the virtual screening process, compounds with promising drug-like properties were chosen using the Lipinski rule of five, and their binding affinities were evaluated by docking studies.

The Effect of Chemical Surface Modification on the Repair Bond Strength of Resin Composite: An In Vitro Study.

This in vitro study investigates the impact of the chemical modification of resin composite surfaces on repair bond strength of micro-hybrid resin composite material. First, 7 mm circular × 3 mm thick resin composite disks were prepared using teflon molds. Then, 50 specimens out of 100 were allocated for stimulated aging using a thermo-cycling (10,000 cycles) device.

Impact of Lifestyle Modifications on Cancer Mortality: A Systematic Review and Meta-Analysis.

: Cancer survival poses significant challenges in oncology, with lifestyle modifications increasingly recognized as crucial in modifying patient outcomes post-diagnosis. This meta-analysis aims to systematically evaluate the impact of various lifestyle interventions on cancer survival across different types of cancer. : A comprehensive literature search of electronic databases including PubMed, Scopus and Cochrane was performed to identify relevant studies up to 30 November 2024.

New Insights in Natural Bioactive Compounds for Periodontal Disease: Advanced Molecular Mechanisms and Therapeutic Potential.

Periodontal disease is a chronic inflammatory condition that destroys the tooth-supporting structures due to the host's immune response to microbial biofilms. Traditional periodontal treatments, such as scaling and root planing, pharmacological interventions, and surgical procedures, have significant limitations, including difficulty accessing deep periodontal pockets, biofilm recolonization, and the development of antibiotic resistance. In light of these challenges, natural bioactive compounds derived from plants, herbs, and other natural sources offer a promising alternative due to their anti-inflammatory, antioxidant, antimicrobial, and tissue-regenerative properties.

The Fetal Effect of Maternal Caffeine Consumption During Pregnancy-A Review.

Caffeine is commonly used to excess by the general public, and most pregnant women drink caffeine on a daily basis, which can become a habit. Maternal caffeine intake during pregnancy is associated with severe gestational outcomes. Due to its lipophilic nature, caffeine can cross the blood-brain barrier, placental barrier, and even amniotic fluid.

Salivary IL-6 as a Biomarker for Early Childhood and Rampant Caries: Insights from a Cross-Sectional Study.

This study aimed to explore the levels of salivary interleukin-6 (IL-6) in children diagnosed with Early Childhood Caries (ECC) and Rampant Caries (RC). Additionally, it sought to determine whether salivary IL-6 levels vary with the increased activity or number of carious lesions in children with ECC and RC. A cross-sectional study was conducted at RAK College of Dental Sciences (RAKCODS), Ras Al Khaimah, UAE.

Intermittent fasting versus continuous caloric restriction for glycemic control and weight loss in type 2 diabetes: A traditional review.

Type 2 Diabetes Mellitus (T2DM) represents a major global health issue, with its incidence anticipated to increase markedly in the forthcoming decades. Efficient non-pharmacological therapies, especially dietary approaches, are essential for regulating glycemic control and facilitating weight reduction. Intermittent Fasting (IF) and Continuous Caloric Restriction (CCR) are two well researched methodologies, but their relative effectiveness and enduring advantages continue to be topics of active discussion.

The Potential Role of Adipose-Derived Stem Cells in Regeneration of Peripheral Nerves.

Peripheral nerve injuries are common complications in surgical and dental practices, often resulting in functional deficiencies and reduced quality of life. Current treatment choices, such as autografts, have limitations, including donor site morbidity and suboptimal outcomes. Adipose-derived stem cells (ADSCs) have shown assuring regenerative potential due to their accessibility, ease of harvesting and propagation, and multipotent properties.

Orthodontic Management of Different Stages and Grades of Periodontitis According to the 2017 Classification of Periodontal Diseases.

The 2017 Periodontal Classification offers a comprehensive framework for the diagnosis and management of periodontitis based on staging and grading criteria. Orthodontic therapy is increasingly incorporated into the management of periodontitis to rectify malocclusion, pathological tooth migration, and occlusal stability. Nonetheless, few data directly correspond with this revised classification scheme.

Comparative Analysis of Whitening Outcomes of Over-the-Counter Toothpastes: An In Vitro Study.

: Whiter teeth are widely accepted as the most beautiful. With the growing demand for whiter teeth, several manufacturers have launched different brands of whitening toothpaste claiming to be effective in removing tooth stains and whitening teeth. The objective of this in vitro study was to evaluate and compare the whitening effect of eight over-the-counter available toothpastes by measuring the changes in color using a digital colorimeter in a simulated staining-brushing cycle model.

The Impact of Ozone on Periodontal Cell Line Viability and Function.

Periodontal diseases, including gingivitis and periodontitis, are chronic inflammatory conditions of the teeth' supporting structures that can lead to progressive tissue destruction and loss if left untreated. Basic treatments like scaling and root planing, alone or combined with antimicrobial agents, are the standard of care. However, with the increasing prevalence of antibiotic resistance and the need for new ideas in therapy, adjunctive treatments like ozone therapy have gained attention.

Endocrine Dysfunction Following Bariatric Surgery: A Systematic Review of Postoperative Changes in Major Endocrine Hormones.

Bariatric surgery (BS) is an effective intervention for obesity and related metabolic disorders, significantly improving metabolic health and alleviating hormonal imbalances. However, it induces complex endocrine changes that can lead to dysfunctions, impacting the somatotropic, gonadal, thyroid, pancreatic, and adrenal axes. This review highlights the dual effects of BS on the endocrine system.

Leveraging Artificial Intelligence to Predict and Manage Complications in Patients With Multimorbidity: A Literature Review.

Artificial intelligence (AI) is revolutionizing healthcare by improving diagnostic accuracy, streamlining treatment protocols, and augmenting patient care, especially in the management of multimorbidity. This review assesses the applications of AI in forecasting and controlling problems in multimorbid patients, emphasizing predictive analytics, real-time data integration, and enhancements in diagnostics. Utilizing extensive datasets from electronic health records and medical imaging, AI models facilitate early complication prediction and prompt therapies in diseases such as cancer, cardiovascular disorders, and diabetes.

A Social Constructionist Influenced Scoping Review of Addictions, Deviance and Crime: Biopsychosocial Perspectives for the Emerging Forensic Mental Health Nursing and Healthcare Services of the Middle East.

Background: Nurses and healthcare professionals employed in correctional and forensic mental health settings encounter unique challenges in the care of their patients due to custodial and restrictive environments.Regions within the Middle East, such as the United Arab Emirates and the Kingdom of Saudi Arabia, have recently experienced exponential economic and healthcare infrastructure development. Mental health has been prioritized for development by recent legislation and practice that incorporate the development of specialist forensic psychiatry services that mediate the need for specialized nurses and allied healthcare staff.

An Evaluation of Neuronal PARP-1 and Caspase-3 Levels in the Brain Tissue of Female Rats Exposed to Electromagnetic Fields at Different Gestational Stages.

Foetal exposure to electromagnetic fields (EMFs) may cause marked neurocognitive impairment, although the mechanisms involved are still unclear. EMF induces region-specific neuronal and astroglial death in the rat hippocampus. Poly (ADP-ribose) polymerase-1 (PARP-1) regulates necrosis, apoptosis and other cellular processes occurring following injury.