Brain Tumors: Development, Drug Resistance, and Sensitization - An Epigenetic Approach.

In this article, we describe contrasting developmental aspects of paediatric and adult brain tumours. We hypothesize that the formation of cancer progenitor cells, for both paediatric and adult, could be due to epigenetic events. However, the progression of adult brain tumours selectively involves more mutations compared to paediatric tumours.

Automatic inoculation of bacterial cultures using low-melting point, wax-like coconut oil.

A simple method for the automatic inoculation of broth culture tubes is described. An incubator is plugged into an electrical outlet timer. Heating of the incubator causes wax-like coconut oil to melt and allow an inoculum-coated bead to drop into sterile liquid medium.

The effects of adding high-intensity of effort resistance training to routine care in persons with type II diabetes: An exploratory randomized parallel-group time-series study.

Aims: This study considered the effects of supervised, low volume, high intensity of effort resistance training compared to continued routine care in persons with type II diabetes.

Methods: We utilized a randomized parallel-group time-series design. All participants completed baseline testing (T0) and then participated in an educational training intervention regarding the management of their diabetes and were followed up for six months, during which they received routine care before being retested (T1).

Emotional Support Animal Assessments: Toward a Standard and Comprehensive Model for Mental Health Professionals.

Growth in the presence of Emotional Support Animals (ESAs) in our society has recently garnered a substantial amount of attention, both in the popular media and the professional literature. Public media abounds with stories focusing on the increasing number of animals claimed as ESAs, the impact of this growth on society, the industry claiming to certify ESAs, and the various types of animals described as "certified." The authors propose an assessment model for ESAs certification comprising a four-pronged approach for conducting these types of assessments: (1) understanding, recognizing, and applying the laws regulating ESAs, (2) a thorough valid assessment of the individual requesting an ESA certification, (3) an assessment of the animal in question to ensure it actually performs the valid functions of an ESA, and (4) an assessment of the interaction between the animal and the individual to determine whether the animal's presence has a demonstrably beneficial effect on that individual.

Historical Analysis: Editors' Reflections on 50 Years of the Journal of Pediatric Psychology.

Objective: This article provides an historical perspective on the Journal of Pediatric Psychology (JPP) on the occasion of its 50th anniversary.

Methods: Former and current editors of JPP participated in a symposium at the 2019 Society of Pediatric Psychology Annual Conference (SPPAC), each highlighting prominent types of articles published during their terms, the influence of these papers over time, and their reflections on the next 50 years of the journal. Their presentations were summarized and integrated for this article.

Medical Child Abuse Hidden in Pediatric Settings: Detection and Intervention.

Medical child abuse, sometimes referred to as Munchausen Syndrome by Proxy or childhood factitious disorder, poses significant diagnostic, intervention, and ethical issues for medical and mental health practitioners alike. Psychologists working in pediatric hospitals and medical clinics should remain mindful of the health and ethical risks posed by these conditions, which are challenging to detect and treat. The surreptitious nature of the conditions and hazards they pose require an integrated medical, psychological, and child protective response.

Sensitization of Drug Resistant Cancer Cells: A Matter of Combination Therapy.

Cancer drug resistance is an enormous problem. It is responsible for most relapses in cancer patients following apparent remission after successful therapy. Understanding cancer relapse requires an understanding of the processes underlying cancer drug resistance.

Neither repetition duration nor number of muscle actions affect strength increases, body composition, muscle size, or fasted blood glucose in trained males and females.

A key variable within resistance training (RT) is that of repetition duration: the time (seconds) taken to perform the concentric and eccentric muscle actions of a repetition. Research has produced equivocal results with regard to strength and muscle mass increases; many studies have created parity in the number of repetitions, but there has been disparity in the load used and the time under load (TUL). The purpose of this study was to compare load- and TUL-matched groups performing resistance exercise using different repetition durations.

Cancer Progenitor Cells: The Result of an Epigenetic Event?

The concept of cancer stem cells was proposed in the late 1990s. Although initially the idea seemed controversial, the existence of cancer stem cells is now well established. However, the process leading to the formation of cancer stem cells is still not clear and thus requires further research.

A minimal dose approach to resistance training for the older adult; the prophylactic for aging.

A plethora of research has supported the numerous health benefits of resistance training as we age, including positive relationships between muscular strength, muscle mass and reduced all-cause mortality. As such, resistance training has been referred to as medicine. However, participation and adherence remains low, with time constraints and perceived difficulty often cited as barriers to resistance training.

Student Perceptions of iPad Applications-Assisted Instruction in Health Professions Education.

The purpose of this study was to examine student's perceptions of the iPad applications-assisted instruction as part of their learning. In this study, multiple features and applications were evaluated as an instructional tool. Fifteen participants responded to the survey indicating their perceptions of the iPad and applications used as part of their course delivery.

Nutrition programs enhance exercise effects on body composition and resting blood pressure.

The purpose of our study was to examine the effects of exercise alone and exercise combined with specific nutrition programs on body composition and resting blood pressure rate. Adult participants (99 women, 22 men; aged 20-86 years) completed a combined strength and endurance exercise program (Exercise Only), or in conjunction with 1 of 2 nutrition plans (Exercise/Protein; Exercise/Protein/Diet). The Exercise-Only group performed 1 set of 9 resistance machines regimens interspersed with 3 bouts of recumbent cycling (5 minutes each).

Resistance training is medicine: effects of strength training on health.

Inactive adults experience a 3% to 8% loss of muscle mass per decade, accompanied by resting metabolic rate reduction and fat accumulation. Ten weeks of resistance training may increase lean weight by 1.4 kg, increase resting metabolic rate by 7%, and reduce fat weight by 1.

Prescribing physical activity: applying the ACSM protocols for exercise type, intensity, and duration across 3 training frequencies.

When physicians advise patients to attain more physical activity, they usually recommend a walking program. However, in a similar way to no exercise, those embarking on a walking program will typically lose 4 to 6 lb of lean weight and reduce their resting metabolic rate 2% to 3% every decade. These effects may be mitigated by the inclusion of resistance exercise.

Stand and deliver: the art of speaking in public.

Anyone who took Latin in high school learned that many English words are derived from Latin roots. One such word is auditorium. It comes from the Latin words audio, which means "to hear," and taurus, which means "the bull.

Life is how you look at it!

Clinical laboratory managers do work that is important and difficult. Sometimes, managers get tired or discouraged. Sometimes, it is hard for them to stay happy.

It's about time.

Managers need more time. They juggle five tasks at once. As they work on one, the other four fall to the ground.

Motivation: the fire within.

This article defines motivation. It tells managers how they can motivate themselves and whether they can motivate others. If managers cannot motivate others, this article explains what they can do instead.