3 results match your criteria: "Queensland University of Technology Woolloongabba[Affiliation]"

Objectives: Globally, non-small cell lung cancer (NSCLC) is the most prevalent form of lung cancer and the leading cause of cancer-related deaths. Tumor-associated circulating cells in NSCLC can have a wide variety of morphological and phenotypic characteristics, including epithelial, immunological or hybrid subtypes. The distinctive characteristics and potential clinical significance of these cells in patients with NSCLC are explored in this study.

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Background: Factors leading to the harmful consumption of substances, like alcohol and sucrose, involve a complex interaction of genes and the environment. While we cannot control the genes we inherit, we can modify our environment. Understanding the role that social and environmental experiences play in alcohol and sucrose consumption is critical for developing preventative interventions and treatments for alcohol use disorders and obesity.

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A Rat Drinking in the Dark Model for Studying Ethanol and Sucrose Consumption.

Front Behav Neurosci

February 2017

Institute of Health and Medical Innovation, Translational Research Institute, Queensland University of Technology Woolloongabba, QLD, Australia.

Article Synopsis
  • The IA2BC and DID models are used to study binge-like alcohol consumption in rodents, with IA2BC traditionally applying to rats and DID to mice.
  • A study found that male Wistar rats drinking from the IA2BC model consumed more ethanol and sucrose per session and per week compared to those in the DID model, despite DID sessions resulting in higher consumption rates per hour.
  • Varenicline effectively reduced alcohol and sugar consumption in the DID model, indicating that it can be a viable method for exploring binge-like consumption in rats, despite its shorter access time.
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