Alpha cell receptor for advanced glycation end products associate with glucagon expression in type 1 diabetes.

Hypoglycemia in type 1 diabetes associates with changes in the pancreatic islet α cells, where the receptor for advanced glycation end products (RAGE) is highly expressed. This study compared islet RAGE expression in donors without diabetes, those at risk of, and those with type 1 diabetes. Laser-dissected islets were subject to RNA bioinformatics and adjacent pancreatic tissue were assessed by confocal microscopy.

Quantitative assessment of dietary intake in adults with Type 1 diabetes following flexible insulin therapy education with an active promotion of dietary freedom.

Unlabelled: Clinical practice guidelines for diabetes include dietary guidelines to address the increased risk of cardiovascular disease.

Aims: To identify impact of flexible insulin education with an active promotion of dietary freedom on energy and macronutrient intake and achievement of nutrient recommendations in adults with Type 1 diabetes.

Methods: Dietary assessment was performed prior to and 12months following flexible insulin education.

Paraparesis secondary to hypokalaemia with hyporeninemic hypoaldosteronism during pregnancy: a diagnostic dilemma.

We report the case of a 22-year-old Ethiopian woman, gravida 1, para 0, who presented at 16 weeks gestation with myalgia and paraparesis.

Disturbed eating behaviours and thoughts in Australian adolescents with type 1 diabetes.

Aim: To describe the presence and type of disturbed eating behaviours and thoughts in a combined male/female Australian sample of adolescents with type 1 diabetes, and examine the association of eating behaviours and thoughts with glycaemic control as evidenced by high glycosylated haemoglobin levels (HbA1c).

Methods: In this cross-sectional descriptive study, 124 adolescents aged 13-18  years were invited to complete three self-administered questionnaires. The Youth Eating Disorder Examination Questionnaire (YEDE-Q) and the Eating Disorder Inventory -3 Risk Composite (EDI-3RC) assessed risk for an eating disorder.

Concurrent validity of self-report measures of eating disorders in adolescents with type 1 diabetes.

Aim: Eating disorder screening tools have not been adequately validated for use with adolescents with type 1 diabetes. This study compared the Youth Eating Disorder Examination-Questionnaire (YEDE-Q) and the Eating Disorder Inventory-3 Risk Composite (EDI-3RC) against the child Eating Disorder Examination (chEDE). These screening tools were chosen because they broadly assess eating disorder psychopathology and have subscales helpful for clinical management.

Headaches and papilloedema in a pregnant woman with polycystic ovarian syndrome.

Idiopathic intracranial hypertension (IIH) is a rare condition, its highest incidence being in obese women of reproductive age. A woman with polycystic ovarian syndrome and IIH is presented, a new diagnosis during pregnancy resulting in a change in her management.

Congenital thyrotoxicosis in premature infants.

Objectives: Graves' disease (GD) complicates 0.1% to 0.2% of pregnancies, but congenital thyrotoxicosis is rare occurring in one in 70 of these pregnancies independent of maternal disease status.