The pancreatic renin-angiotensin system: does it play a role in endocrine oncology?

The characterization of a local renin-angiotensin system in the pancreas has attracted much attention because of its potential clinical applications. A pancreatic renin-angiotensin system may be present in humans and may interact with islet cells. Nevertheless, our knowledge of the renin-angiotensin system in the human pancreas is still in its infancy, especially in the field of endocrine oncology.

Clinics in diagnostic imaging (32). Opportunistic pneumonia in acquired immunodeficiency syndrome (AIDS).

A 24-year old HIV-positive patient presented with fever and productive cough. Chest radiograph showed a cavitating pulmonary infiltrate. Diagnosis of Nocardosis was made from modified acid-fast stain of his sputum specimen.

Prenatal quantitation of number of X-chromosomes by slot blot hybridization and autoradiography.

Objective: To study the use of slot blot hybridization as a method of prenatal quantification of the number of X-chromosomes in chorionic villi samples.

Method: DNA of chorionic villi from fetuses with karyotypes of 46,XY; 45,XO; 47,XXX; 69,XXX and 48,XXXX were extracted, slot blotted and hybridized to the following radioactive probes: beta 0.9, FVIII, pY3.